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| | TNFRSF4 | TNF receptor superfamily member 4. (254 aa) |
| | FCRL3 | Fc receptor like 3. (742 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (420 aa) |
| | CD24 | CD24 molecule. (129 aa) |
| | FOXP3 | Forkhead box P3. (441 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | CD276 | Ig-like domain-containing protein. (280 aa) |
| | TACR1 | Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa) |
| | CSF2RA | Uncharacterized protein. (262 aa) |
| | NMB | Uncharacterized protein. (185 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (301 aa) |
| | IGFBP2 | Thyroglobulin type-1 domain-containing protein. (181 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (917 aa) |
| | ADA | Adenosine deaminase. (412 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (339 aa) |
| | TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (285 aa) |
| | CLECL1 | C-type lectin like 1. (192 aa) |
| | DHPS | Uncharacterized protein. (369 aa) |
| | ENSPPAP00000004994 | TNF receptor-associated factor. (475 aa) |
| | TFRC | Transferrin receptor. (773 aa) |
| | ENSPPAP00000004806 | Uncharacterized protein. (142 aa) |
| | IL23R | Interleukin 23 receptor. (629 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | IL6ST | Interleukin 6 signal transducer. (928 aa) |
| | JAK2 | Tyrosine-protein kinase. (1143 aa) |
| | IGF1 | IlGF domain-containing protein. (196 aa) |
| | TICAM1 | RHIM domain-containing protein. (541 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (646 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (715 aa) |
| | CCR2 | C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | IL7 | Interleukin 7. (179 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | TIRAP | TIR domain-containing protein. (226 aa) |
| | DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (480 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | SELENOK | Selenoprotein K. (89 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | BST2 | Uncharacterized protein. (185 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | BST1 | Bone marrow stromal cell antigen 1. (332 aa) |
| | FADD | Death domain-containing protein. (144 aa) |
| | CD274 | CD274 molecule. (290 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1261 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | ENSPPAP00000020965 | KH type-2 domain-containing protein. (250 aa) |
| | HHLA2 | HERV-H LTR-associating 2. (414 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa) |
| | TMIGD2 | Transmembrane and immunoglobulin domain containing 2. (282 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | EPHB2 | EPH receptor B2. (1039 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | ST6GAL1 | ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | CCDC88B | Coiled-coil domain containing 88B. (1347 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) |
| | MIF | Macrophage migration inhibitory factor. (115 aa) |
| | BCL2 | BCL2 apoptosis regulator. (193 aa) |
| | HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) |
| | CD1D | CD1d molecule. (335 aa) |
| | CD3E | CD3e molecule. (207 aa) |
| | CHRNB2 | Cholinergic receptor nicotinic beta 2 subunit. (502 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | CD320 | CD320 molecule. (282 aa) |
| | ENSPPAP00000016729 | Ribosomal_S3_C domain-containing protein. (100 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (356 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2. (273 aa) |
| | CD81 | Tetraspanin. (270 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | LYN | Tyrosine-protein kinase. (526 aa) |
| | ZP4 | Zona pellucida glycoprotein 4. (540 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (758 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1832 aa) |
| | CD70 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (193 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2338 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | IL12RB2 | Interleukin 12 receptor subunit beta 2. (740 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | NMBR | Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (570 aa) |
| | IL5RA | Interleukin 5 receptor subunit alpha. (423 aa) |
| | IL34 | Interleukin 34. (242 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (253 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | IL23A | Interleukin 23 subunit alpha. (189 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (549 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | SLC39A10 | Solute carrier family 39 member 10. (831 aa) |
| | ZNF335 | Zinc finger protein 335. (1342 aa) |
| | RASAL3 | RAS protein activator like 3. (933 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (258 aa) |
| | CSF2 | Colony stimulating factor 2. (144 aa) |
| | ZP3 | Zona pellucida glycoprotein 3. (373 aa) |
| | JAK3 | Tyrosine-protein kinase. (1090 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (912 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (904 aa) |
| | OCSTAMP | Osteoclast stimulatory transmembrane protein. (548 aa) |
| | EFNB1 | Ephrin B1; Belongs to the ephrin family. (346 aa) |
| | LGALS9 | Galectin. (355 aa) |
| | TCF3 | Transcription factor 3. (673 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | STAT5B | Signal transducer and activator of transcription. (789 aa) |
| | CD40 | CD40 molecule. (277 aa) |
| | ENSPPAP00000033446 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (253 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (482 aa) |
| | CD80 | CD80 molecule. (288 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | TYK2 | Tyrosine-protein kinase. (1190 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1127 aa) |
| | BTK | Tyrosine-protein kinase. (693 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (352 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (311 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | CD6 | CD6 molecule. (644 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | CD74 | CD74 molecule. (296 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (636 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (629 aa) |
| | IL2RA | Sushi domain-containing protein. (249 aa) |
| | ICOSLG | Uncharacterized protein. (463 aa) |
| | TNFRSF13C | Uncharacterized protein. (112 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | CD38 | CD38 molecule. (300 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (807 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | IL6 | Uncharacterized protein. (198 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (662 aa) |
| | CLCF1 | Uncharacterized protein. (322 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
