STRINGSTRING
KCNAB2 KCNAB2 CD47 CD47 OLR1 OLR1 SNAP23 SNAP23 RAP2B RAP2B MGAM MGAM FCER1G FCER1G STX7 STX7 PTAFR PTAFR GAA GAA UBR4 UBR4 LTF LTF ENSPPAP00000004425 ENSPPAP00000004425 SLC2A3 SLC2A3 TARM1 TARM1 LOC100986914 LOC100986914 ENSPPAP00000003604 ENSPPAP00000003604 PKP1 PKP1 LOC100978613 LOC100978613 SIGLEC14 SIGLEC14 LTA4H LTA4H ENSPPAP00000002253 ENSPPAP00000002253 GPR84 GPR84 PTPRN2 PTPRN2 ENSPPAP00000001059 ENSPPAP00000001059 LOC106634416 LOC106634416 ILF2 ILF2 CLEC12A CLEC12A FOLR3 FOLR3 SERPINB6 SERPINB6 NBEAL2 NBEAL2 ATP8B4 ATP8B4 ADAM8 ADAM8 SERPINB10 SERPINB10 ENSPPAP00000040216 ENSPPAP00000040216 TBC1D10C TBC1D10C SVIP SVIP TCN1 TCN1 PPBP PPBP HGSNAT HGSNAT CDA CDA DSG1 DSG1 CRISP3 CRISP3 PTPRB PTPRB ATP6V0C ATP6V0C ITGAX ITGAX CNN2 CNN2 CTSH CTSH LAMTOR1 LAMTOR1 LOC103784118 LOC103784118 CHIT1 CHIT1 CD300A CD300A ADAM10 ADAM10 ENSPPAP00000035079 ENSPPAP00000035079 CD93 CD93 ATP6AP2 ATP6AP2 PRG3 PRG3 CFP CFP IDH1 IDH1 CEACAM8 CEACAM8 GSDMD GSDMD TMEM179B TMEM179B NCKAP1L NCKAP1L MMP9 MMP9 CD53 CD53 HP HP RAP2C RAP2C METTL7A METTL7A CLEC4D CLEC4D NRAS NRAS COPB1 COPB1 STXBP2 STXBP2 CLEC5A CLEC5A LAMTOR2 LAMTOR2 ITGAM ITGAM PGM1 PGM1 SPTAN1 SPTAN1 GGH GGH CD58 CD58 CD59 CD59 DSC1 DSC1 TRPM2 TRPM2 CD33 CD33 ANO6 ANO6 DYNC1LI1 DYNC1LI1 CLEC4C CLEC4C OLFM4 OLFM4 DYNLL1 DYNLL1 ARMC8 ARMC8 PRCP PRCP OSCAR OSCAR PTX3 PTX3 SLC11A1 SLC11A1 TMEM63A TMEM63A LAMP1 LAMP1 FOLR2 FOLR2 VAMP1 VAMP1 GOLGA7 GOLGA7 ATP6V0A1 ATP6V0A1 LAMTOR3 LAMTOR3 LAIR1 LAIR1 CEACAM1 CEACAM1 ITGB2 ITGB2 STOM STOM LOC100989777 LOC100989777 LGALS3 LGALS3 STBD1 STBD1 ADGRE3 ADGRE3 MCEMP1 MCEMP1 RAC1 RAC1 LOC100974147 LOC100974147 ENPP4 ENPP4 QPCT QPCT ATP11A ATP11A DBNL DBNL PLD1 PLD1 RAB14 RAB14 STXBP3 STXBP3 LOC100967790 LOC100967790 CYSTM1 CYSTM1 ARL8A ARL8A DSP DSP VAMP8 VAMP8 TSPAN14 TSPAN14 TIMP2 TIMP2 SIRPA SIRPA CXCL1 CXCL1 AP2A2 AP2A2 QSOX1 QSOX1 CTSS CTSS TCIRG1 TCIRG1 DOK3 DOK3 CANT1 CANT1 TNFAIP6 TNFAIP6 FTH1 FTH1 YPEL5 YPEL5 DIAPH1 DIAPH1 CHRNB4 CHRNB4 ENSPPAP00000012431 ENSPPAP00000012431 MMP8 MMP8 SIRPB1 SIRPB1 LRG1 LRG1 LAMP2 LAMP2 NFASC NFASC VPS35L VPS35L FRMPD3 FRMPD3 CYBB CYBB NIT2 NIT2 ENSPPAP00000009349 ENSPPAP00000009349 PTPN6 PTPN6 CYFIP1 CYFIP1 SERPINB12 SERPINB12 FCAR FCAR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
CD47CD47 molecule. (307 aa)
OLR1Oxidized low density lipoprotein receptor 1. (273 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
MGAMUncharacterized protein. (2753 aa)
FCER1GUncharacterized protein. (112 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
PTAFRPlatelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (952 aa)
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5183 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
ENSPPAP00000004425Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (162 aa)
SLC2A3Solute carrier family 2 member 3; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (433 aa)
TARM1T cell-interacting, activating receptor on myeloid cells 1. (273 aa)
LOC100986914Uncharacterized protein. (210 aa)
ENSPPAP00000003604Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (113 aa)
PKP1Plakophilin 1. (747 aa)
LOC100978613Dynein light chain. (89 aa)
SIGLEC14Sialic acid binding Ig like lectin 14. (401 aa)
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (607 aa)
ENSPPAP00000002253Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (173 aa)
GPR84G protein-coupled receptor 84. (396 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (977 aa)
ENSPPAP00000001059Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (113 aa)
LOC106634416Uncharacterized protein. (144 aa)
ILF2Interleukin enhancer binding factor 2. (390 aa)
CLEC12AC-type lectin domain family 12 member A. (275 aa)
FOLR3Folate receptor gamma. (245 aa)
SERPINB6Serpin family B member 6; Belongs to the serpin family. (412 aa)
NBEAL2Neurobeachin like 2. (2734 aa)
ATP8B4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1099 aa)
ADAM8ADAM metallopeptidase domain 8. (816 aa)
SERPINB10Serpin family B member 10; Belongs to the serpin family. (397 aa)
ENSPPAP00000040216MFS domain-containing protein. (228 aa)
TBC1D10CTBC1 domain family member 10C. (446 aa)
SVIPSmall VCP interacting protein. (77 aa)
TCN1Transcobalamin 1. (433 aa)
PPBPC-X-C motif chemokine. (128 aa)
HGSNATUncharacterized protein. (339 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1048 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (278 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2215 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (246 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
LOC103784118Lipocln_cytosolic_FA-bd_dom domain-containing protein. (141 aa)
CHIT1Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (366 aa)
CD300ACD300a molecule. (299 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ENSPPAP00000035079Uncharacterized protein. (513 aa)
CD93CD93 molecule. (650 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
PRG3Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa)
CFPComplement factor properdin. (469 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
CEACAM8Carcinoembryonic antigen related cell adhesion molecule 8. (349 aa)
GSDMDGasdermin D. (533 aa)
TMEM179BTransmembrane protein 179B. (187 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
CD53Tetraspanin. (219 aa)
HPHaptoglobin; Belongs to the peptidase S1 family. (348 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
METTL7AMethyltransferase like 7A. (244 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
COPB1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
STXBP2Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (640 aa)
CLEC5AC-type lectin domain containing 5A. (188 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
PGM1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (580 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
CD58CD58 molecule. (250 aa)
CD59UPAR/Ly6 domain-containing protein. (152 aa)
DSC1Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (894 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
CD33CD33 molecule. (364 aa)
ANO6Anoctamin. (906 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
CLEC4CC-type lectin domain family 4 member C. (201 aa)
OLFM4Olfactomedin 4. (510 aa)
DYNLL1Dynein light chain. (89 aa)
ARMC8Armadillo repeat containing 8. (672 aa)
PRCPProlylcarboxypeptidase. (496 aa)
OSCAROsteoclast associated Ig-like receptor. (300 aa)
PTX3Pentraxin 3. (380 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
TMEM63ATransmembrane protein 63A. (807 aa)
LAMP1Lysosomal associated membrane protein 1. (465 aa)
FOLR2Folate receptor beta. (255 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
GOLGA7Golgin A7. (143 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
LAIR1Leukocyte associated immunoglobulin like receptor 1. (270 aa)
CEACAM1Uncharacterized protein. (464 aa)
ITGB2Integrin beta. (806 aa)
STOMStomatin. (288 aa)
LOC100989777Uncharacterized protein. (191 aa)
LGALS3Galectin. (250 aa)
STBD1Starch binding domain 1. (358 aa)
ADGRE3Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (590 aa)
MCEMP1Mast cell expressed membrane protein 1. (204 aa)
RAC1Uncharacterized protein. (224 aa)
LOC100974147Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (165 aa)
ENPP4Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa)
QPCTGlutaminyl-peptide cyclotransferase. (361 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1192 aa)
DBNLDrebrin like. (489 aa)
PLD1Phospholipase. (1074 aa)
RAB14RAB14, member RAS oncogene family. (212 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (524 aa)
LOC100967790Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (663 aa)
CYSTM1Cysteine rich transmembrane module containing 1. (97 aa)
ARL8AADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
DSPDesmoplakin. (2871 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
TSPAN14Tetraspanin. (270 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (176 aa)
SIRPASignal regulatory protein alpha. (504 aa)
CXCL1C-X-C motif chemokine. (107 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (943 aa)
QSOX1Sulfhydryl oxidase. (817 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
DOK3Docking protein 3. (440 aa)
CANT1Calcium activated nucleotidase 1. (401 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (146 aa)
YPEL5Protein yippee-like; Belongs to the yippee family. (121 aa)
DIAPH1FH2 domain-containing protein. (507 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (498 aa)
ENSPPAP00000012431Calponin-homology (CH) domain-containing protein. (357 aa)
MMP8Matrix metallopeptidase 8. (467 aa)
SIRPB1Uncharacterized protein. (427 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
LAMP2Lysosomal associated membrane protein 2. (411 aa)
NFASCNeurofascin. (1338 aa)
VPS35LVPS35 endosomal protein sorting factor like. (1052 aa)
FRMPD3FERM and PDZ domain containing 3. (1810 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
NIT2Nitrilase family member 2. (280 aa)
ENSPPAP00000009349Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (157 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SERPINB12Serpin family B member 12; Belongs to the serpin family. (425 aa)
FCARFc fragment of IgA receptor. (286 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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