70 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC2A3	Solute carrier family 2 member 3; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (433 aa)
	SERPINB6	Serpin family B member 6; Belongs to the serpin family. (412 aa)
	NBEAL2	Neurobeachin like 2. (2734 aa)
	ATP8B4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1099 aa)
	ADAM8	ADAM metallopeptidase domain 8. (816 aa)
	ENSPPAP00000040216	MFS domain-containing protein. (228 aa)
	SVIP	Small VCP interacting protein. (77 aa)
	HGSNAT	Uncharacterized protein. (339 aa)
	PTPRB	Protein tyrosine phosphatase receptor type B. (2215 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	ITGAX	Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa)
	CD300A	CD300a molecule. (299 aa)
	ADAM10	ADAM metallopeptidase domain 10. (748 aa)
	ENSPPAP00000035079	Uncharacterized protein. (513 aa)
	CD93	CD93 molecule. (650 aa)
	ATP6AP2	ATPase H+ transporting accessory protein 2. (350 aa)
	CEACAM8	Carcinoembryonic antigen related cell adhesion molecule 8. (349 aa)
	CD53	Tetraspanin. (219 aa)
	RAP2C	RAP2C, member of RAS oncogene family. (183 aa)
	CLEC4D	C-type lectin domain family 4 member D. (215 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	COPB1	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
	CLEC5A	C-type lectin domain containing 5A. (188 aa)
	LAMTOR2	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
	ITGAM	Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
	CD59	UPAR/Ly6 domain-containing protein. (152 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1552 aa)
	CD33	CD33 molecule. (364 aa)
	ANO6	Anoctamin. (906 aa)
	CLEC4C	C-type lectin domain family 4 member C. (201 aa)
	DYNLL1	Dynein light chain. (89 aa)
	SLC11A1	Solute carrier family 11 member 1. (550 aa)
	TMEM63A	Transmembrane protein 63A. (807 aa)
	VAMP1	Vesicle associated membrane protein 1. (118 aa)
	LAMTOR3	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
	LAIR1	Leukocyte associated immunoglobulin like receptor 1. (270 aa)
	CEACAM1	Uncharacterized protein. (464 aa)
	ITGB2	Integrin beta. (806 aa)
	STOM	Stomatin. (288 aa)
	STBD1	Starch binding domain 1. (358 aa)
	MCEMP1	Mast cell expressed membrane protein 1. (204 aa)
	ATP11A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1192 aa)
	PLD1	Phospholipase. (1074 aa)
	RAB14	RAB14, member RAS oncogene family. (212 aa)
	CYSTM1	Cysteine rich transmembrane module containing 1. (97 aa)
	VAMP8	Vesicle associated membrane protein 8. (100 aa)
	TSPAN14	Tetraspanin. (270 aa)
	SIRPA	Signal regulatory protein alpha. (504 aa)
	CHRNB4	Cholinergic receptor nicotinic beta 4 subunit. (498 aa)
	SIRPB1	Uncharacterized protein. (427 aa)
	FRMPD3	FERM and PDZ domain containing 3. (1810 aa)
	CYBB	Cytochrome b-245 beta chain. (570 aa)
	KCNAB2	Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
	FCAR	Fc fragment of IgA receptor. (286 aa)
	CD47	CD47 molecule. (307 aa)
	OLR1	Oxidized low density lipoprotein receptor 1. (273 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
	RAP2B	RAP2B, member of RAS oncogene family. (183 aa)
	MGAM	Uncharacterized protein. (2753 aa)
	FCER1G	Uncharacterized protein. (112 aa)
	PTAFR	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
	GAA	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (952 aa)
	UBR4	Ubiquitin protein ligase E3 component n-recognin 4. (5183 aa)
	TARM1	T cell-interacting, activating receptor on myeloid cells 1. (273 aa)
	LOC100986914	Uncharacterized protein. (210 aa)
	LOC100978613	Dynein light chain. (89 aa)
	SIGLEC14	Sialic acid binding Ig like lectin 14. (401 aa)
	GPR84	G protein-coupled receptor 84. (396 aa)
	LOC106634416	Uncharacterized protein. (144 aa)
	CLEC12A	C-type lectin domain family 12 member A. (275 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	TSPAN14	ENSPPAP00000035320	ENSPPAP00000015763	ADAM metallopeptidase domain 10.	Tetraspanin.	0.834
ATP11A	ATP8B4	ENSPPAP00000017944	ENSPPAP00000041999	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.416
ATP6AP2	ATP6V0C	ENSPPAP00000034370	ENSPPAP00000037279	ATPase H+ transporting accessory protein 2.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.966
ATP6V0C	ATP6AP2	ENSPPAP00000037279	ENSPPAP00000034370	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 2.	0.966
ATP6V0C	COPB1	ENSPPAP00000037279	ENSPPAP00000029766	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.557
ATP6V0C	DYNLL1	ENSPPAP00000037279	ENSPPAP00000025298	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Dynein light chain.	0.419
ATP6V0C	LAMTOR2	ENSPPAP00000037279	ENSPPAP00000028951	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.679
ATP6V0C	LAMTOR3	ENSPPAP00000037279	ENSPPAP00000022602	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.683
ATP6V0C	LOC100978613	ENSPPAP00000037279	ENSPPAP00000002720	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Dynein light chain.	0.419
ATP8B4	ATP11A	ENSPPAP00000041999	ENSPPAP00000017944	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.416
CD300A	ITGB2	ENSPPAP00000035496	ENSPPAP00000021180	CD300a molecule.	Integrin beta.	0.452
CD300A	LAIR1	ENSPPAP00000035496	ENSPPAP00000022085	CD300a molecule.	Leukocyte associated immunoglobulin like receptor 1.	0.439
CD33	CD47	ENSPPAP00000026834	ENSPPAP00000007759	CD33 molecule.	CD47 molecule.	0.542
CD33	CEACAM8	ENSPPAP00000026834	ENSPPAP00000032169	CD33 molecule.	Carcinoembryonic antigen related cell adhesion molecule 8.	0.554
CD33	CLEC12A	ENSPPAP00000026834	ENSPPAP00000000186	CD33 molecule.	C-type lectin domain family 12 member A.	0.617
CD33	ITGAM	ENSPPAP00000026834	ENSPPAP00000028433	CD33 molecule.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.688
CD33	ITGAX	ENSPPAP00000026834	ENSPPAP00000036667	CD33 molecule.	Integrin subunit alpha X; Belongs to the integrin alpha chain family.	0.560
CD33	LAIR1	ENSPPAP00000026834	ENSPPAP00000022085	CD33 molecule.	Leukocyte associated immunoglobulin like receptor 1.	0.445
CD33	SIRPA	ENSPPAP00000026834	ENSPPAP00000014938	CD33 molecule.	Signal regulatory protein alpha.	0.473
CD33	SIRPB1	ENSPPAP00000026834	ENSPPAP00000011987	CD33 molecule.	Uncharacterized protein.	0.473