(15 nodes) Left/right axis specification network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZIC3	Zic family member 3. (466 aa)
	NOTCH2	Notch receptor 2. (2254 aa)
	ARL13B	ADP ribosylation factor like GTPase 13B. (428 aa)
	HSPB11	Uncharacterized protein. (214 aa)
	AHI1	Abelson helper integration site 1. (1240 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (771 aa)
	MNS1	Meiosis specific nuclear structural 1. (494 aa)
	PKD1L1	Polycystin 1 like 1, transient receptor potential channel interacting. (2854 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (624 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (733 aa)
	NOTCH1	Notch receptor 1. (2573 aa)
	SETDB2	SET domain bifurcated histone lysine methyltransferase 2. (719 aa)
	PITX2	Homeobox protein. (354 aa)
	IFT172	Intraflagellar transport 172. (1767 aa)
	CITED2	Uncharacterized protein. (179 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHI1	ARL13B	ENSPPAP00000018060	ENSPPAP00000005789	Abelson helper integration site 1.	ADP ribosylation factor like GTPase 13B.	0.690
ARL13B	AHI1	ENSPPAP00000005789	ENSPPAP00000018060	ADP ribosylation factor like GTPase 13B.	Abelson helper integration site 1.	0.690
ARL13B	IFT172	ENSPPAP00000005789	ENSPPAP00000040400	ADP ribosylation factor like GTPase 13B.	Intraflagellar transport 172.	0.459
ARL13B	SMO	ENSPPAP00000005789	ENSPPAP00000018211	ADP ribosylation factor like GTPase 13B.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.635
DLL1	NOTCH1	ENSPPAP00000028099	ENSPPAP00000033437	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1.	0.998
DLL1	NOTCH2	ENSPPAP00000028099	ENSPPAP00000013961	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.995
HSPB11	IFT172	ENSPPAP00000014119	ENSPPAP00000040400	Uncharacterized protein.	Intraflagellar transport 172.	0.977
IFT172	ARL13B	ENSPPAP00000040400	ENSPPAP00000005789	Intraflagellar transport 172.	ADP ribosylation factor like GTPase 13B.	0.459
IFT172	HSPB11	ENSPPAP00000040400	ENSPPAP00000014119	Intraflagellar transport 172.	Uncharacterized protein.	0.977
IFT172	SMO	ENSPPAP00000040400	ENSPPAP00000018211	Intraflagellar transport 172.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.483
NOTCH1	DLL1	ENSPPAP00000033437	ENSPPAP00000028099	Notch receptor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.998
NOTCH1	NOTCH2	ENSPPAP00000033437	ENSPPAP00000013961	Notch receptor 1.	Notch receptor 2.	0.947
NOTCH1	SMO	ENSPPAP00000033437	ENSPPAP00000018211	Notch receptor 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.405
NOTCH2	DLL1	ENSPPAP00000013961	ENSPPAP00000028099	Notch receptor 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.995
NOTCH2	NOTCH1	ENSPPAP00000013961	ENSPPAP00000033437	Notch receptor 2.	Notch receptor 1.	0.947
PITX2	ZIC3	ENSPPAP00000036121	ENSPPAP00000013687	Homeobox protein.	Zic family member 3.	0.534
SMO	ARL13B	ENSPPAP00000018211	ENSPPAP00000005789	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	ADP ribosylation factor like GTPase 13B.	0.635
SMO	IFT172	ENSPPAP00000018211	ENSPPAP00000040400	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Intraflagellar transport 172.	0.483
SMO	NOTCH1	ENSPPAP00000018211	ENSPPAP00000033437	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Notch receptor 1.	0.405
ZIC3	PITX2	ENSPPAP00000013687	ENSPPAP00000036121	Zic family member 3.	Homeobox protein.	0.534