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| | FIP1L1 | Fip1 domain-containing protein. (603 aa) |
| | RNASEL | Ribonuclease L. (741 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (1078 aa) |
| | TATDN2 | Uncharacterized protein. (761 aa) |
| | TDP1 | Tyrosyl-DNA phosphodiesterase 1. (608 aa) |
| | ANGEL1 | Angel homolog 1. (668 aa) |
| | OGG1 | ENDO3c domain-containing protein. (345 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | LOC100976089 | Bms1-type G domain-containing protein. (186 aa) |
| | TDP2 | Tyrosyl-DNA phosphodiesterase 2. (362 aa) |
| | MGME1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family. (344 aa) |
| | FANCM | FA complementation group M. (2048 aa) |
| | ISG20 | Interferon stimulated exonuclease gene 20. (179 aa) |
| | NYNRIN | NYN domain and retroviral integrase containing. (1898 aa) |
| | NHP2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa) |
| | UTP23 | UTP23 small subunit processome component. (249 aa) |
| | PGBD5 | PiggyBac transposable element derived 5. (455 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (282 aa) |
| | ERI2 | ERI1 exoribonuclease family member 2. (660 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (908 aa) |
| | CPSF7 | Cleavage and polyadenylation specific factor 7. (489 aa) |
| | ENSPPAP00000009956 | Uncharacterized protein. (245 aa) |
| | RNASEH2A | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (299 aa) |
| | ASTE1 | Asteroid homolog 1. (704 aa) |
| | REXO4 | REX4 homolog, 3'-5' exonuclease. (422 aa) |
| | BMS1 | BMS1 ribosome biogenesis factor. (1260 aa) |
| | PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (743 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (466 aa) |
| | DDX1 | DEAD-box helicase 1. (740 aa) |
| | CSTF3 | Cleavage stimulation factor subunit 3. (697 aa) |
| | EXOSC8 | Exosome component 8. (276 aa) |
| | ENSPPAP00000007423 | Uncharacterized protein. (232 aa) |
| | PNLDC1 | PARN like, ribonuclease domain containing 1. (531 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (790 aa) |
| | SLFN12L | Schlafen family member 12 like. (617 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (895 aa) |
| | TTC38 | Tetratricopeptide repeat domain 38. (469 aa) |
| | ENSPPAP00000006330 | Uncharacterized protein. (251 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (706 aa) |
| | RRS1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa) |
| | MUS81 | MUS81 structure-specific endonuclease subunit. (551 aa) |
| | EXOSC5 | Exosome component 5. (235 aa) |
| | RPP40 | Ribonuclease P/MRP subunit p40. (363 aa) |
| | TRIR | Telomerase RNA component interacting RNase. (172 aa) |
| | TREX1 | Three prime repair exonuclease 1. (369 aa) |
| | CNOT1 | CCR4-NOT transcription complex subunit 1. (2383 aa) |
| | RNASE8 | Ribonuclease A family member 8; Belongs to the pancreatic ribonuclease family. (155 aa) |
| | SWT1 | SWT1 RNA endoribonuclease homolog. (900 aa) |
| | ENSPPAP00000004806 | Uncharacterized protein. (142 aa) |
| | DIS3L | DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1058 aa) |
| | CPSF1 | Cleavage and polyadenylation specific factor 1. (1450 aa) |
| | RNASE11 | Ribonuclease A family member 11 (inactive); Belongs to the pancreatic ribonuclease family. (199 aa) |
| | PLD3 | Phospholipase D family member 3. (490 aa) |
| | PIWIL1 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (861 aa) |
| | MEI4 | Meiotic double-stranded break formation protein 4. (385 aa) |
| | POP1 | POP1 homolog, ribonuclease P/MRP subunit. (1023 aa) |
| | ENSPPAP00000004030 | Uncharacterized protein. (272 aa) |
| | POP7 | Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa) |
| | PMS2 | PMS1 homolog 2, mismatch repair system component. (771 aa) |
| | LACTB2 | Lactamase beta 2. (287 aa) |
| | DNASE1L1 | Deoxyribonuclease; Belongs to the DNase I family. (302 aa) |
| | PNKP | Polynucleotide kinase 3'-phosphatase. (521 aa) |
| | ELAC2 | ElaC ribonuclease Z 2. (826 aa) |
| | DFFB | DNA fragmentation factor subunit beta. (362 aa) |
| | XRN1 | 5'-3' exoribonuclease 1. (1706 aa) |
| | RPP25 | Ribonuclease P and MRP subunit p25. (199 aa) |
| | SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa) |
| | PCF11 | PCF11 cleavage and polyadenylation factor subunit. (1686 aa) |
| | SLFN12 | Schlafen family member 12. (579 aa) |
| | RNASE1 | Ribonuclease A family member 1, pancreatic; Belongs to the pancreatic ribonuclease family. (156 aa) |
| | HORMAD1 | HORMA domain containing 1. (394 aa) |
| | CPSF6 | Cleavage and polyadenylation specific factor 6. (566 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (875 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (312 aa) |
| | LOC100978496 | RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (390 aa) |
| | ZGRF1 | Zinc finger GRF-type containing 1. (2103 aa) |
| | ENSPPAP00000000720 | Uncharacterized protein. (96 aa) |
| | PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1198 aa) |
| | UTP20 | UTP20 small subunit processome component. (2785 aa) |
| | TBL3 | Transducin beta like 3. (808 aa) |
| | ZC3H12C | Zinc finger CCCH-type containing 12C. (884 aa) |
| | PLD4 | Phospholipase D family member 4. (515 aa) |
| | DIS3 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa) |
| | ENSPPAP00000038146 | Uncharacterized protein. (66 aa) |
| | CCDC36 | Coiled-coil domain containing 36. (543 aa) |
| | RPP38 | Ribonuclease P/MRP subunit p38. (311 aa) |
| | C12orf10 | Chromosome 12 open reading frame 10. (376 aa) |
| | ZC3H12D | Zinc finger CCCH-type containing 12D. (526 aa) |
| | DXO | Decapping exoribonuclease. (396 aa) |
| | ENDOG | Endonuclease. (188 aa) |
| | RPP14 | Ribonuclease P/MRP subunit p14. (124 aa) |
| | MARF1 | Meiosis regulator and mRNA stability factor 1. (1742 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | ENSPPAP00000036339 | Uncharacterized protein. (244 aa) |
| | PRORP | PRORP domain-containing protein. (583 aa) |
| | BIVM | BIVM-ERCC5 readthrough. (1640 aa) |
| | N4BP2L1 | NEDD4 binding protein 2 like 1. (244 aa) |
| | ENSPPAP00000035415 | Uncharacterized protein. (689 aa) |
| | XPA | XPA, DNA damage recognition and repair factor. (273 aa) |
| | POP4 | Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (220 aa) |
| | ENSPPAP00000034890 | Uncharacterized protein. (126 aa) |
| | NOB1 | RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (412 aa) |
| | KRI1 | KRI1 homolog. (705 aa) |
| | EDC3 | Enhancer of mRNA decapping 3. (508 aa) |
| | ENSPPAP00000034340 | NTF2 domain-containing protein. (394 aa) |
| | SETMAR | SET domain and mariner transposase fusion gene. (684 aa) |
| | REXO2 | RNA exonuclease 2. (237 aa) |
| | CPSF2 | Cleavage and polyadenylation specificity factor subunit 2. (782 aa) |
| | AEN | Apoptosis enhancing nuclease. (325 aa) |
| | ENSPPAP00000033446 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (253 aa) |
| | ZC3H12B | Zinc finger CCCH-type containing 12B. (836 aa) |
| | RNASEK | Ribonuclease K. (137 aa) |
| | SLFN13 | Schlafen family member 13. (897 aa) |
| | PELO | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa) |
| | NOP9 | NOP9 nucleolar protein. (634 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break w [...] (318 aa) |
| | EXO1 | Exonuclease 1. (846 aa) |
| | ENSPPAP00000031085 | Uncharacterized protein. (277 aa) |
| | EXOSC10 | Exosome component 10. (890 aa) |
| | POLR3K | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa) |
| | SAMHD1 | SAM domain and HD domain-containing protein 1. (626 aa) |
| | INTS11 | Integrator complex subunit 11. (606 aa) |
| | RCL1 | RNA terminal phosphate cyclase like 1. (373 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (873 aa) |
| | ENSPPAP00000029659 | Uncharacterized protein. (176 aa) |
| | ENSPPAP00000029406 | Uncharacterized protein. (165 aa) |
| | NOP14 | NOP14 nucleolar protein. (857 aa) |
| | ANKLE1 | Ankyrin repeat and LEM domain containing 1. (669 aa) |
| | MBLAC1 | Metallo-beta-lactamase domain containing 1. (250 aa) |
| | DROSHA | Drosha ribonuclease III. (1369 aa) |
| | HELZ2 | Helicase with zinc finger 2. (2649 aa) |
| | PLSCR1 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (314 aa) |
| | LRRC27 | Leucine rich repeat containing 27. (530 aa) |
| | ATRIP | ATR interacting protein. (790 aa) |
| | TUT1 | RRM domain-containing protein. (912 aa) |
| | CNOT7 | CCR4-NOT transcription complex subunit 7. (285 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (926 aa) |
| | DNASE1L2 | Deoxyribonuclease; Belongs to the DNase I family. (299 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1060 aa) |
| | CPSF4L | Uncharacterized protein. (152 aa) |
| | TSEN34 | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (315 aa) |
| | WRN | WRN RecQ like helicase. (1405 aa) |
| | ENDOU | Endonuclease, poly(U) specific. (433 aa) |
| | PPP1R8 | Protein phosphatase 1 regulatory subunit 8. (349 aa) |
| | ELAC1 | ElaC ribonuclease Z 1. (363 aa) |
| | NCBP2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa) |
| | NUDT12 | Nudix hydrolase 12. (462 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) |
| | DCLRE1C | DNA cross-link repair 1C. (590 aa) |
| | ARID3A | Uncharacterized protein. (373 aa) |
| | USB1 | U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (265 aa) |
| | DCP2 | Decapping mRNA 2. (417 aa) |
| | FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1017 aa) |
| | FCF1 | FCF1 rRNA-processing protein. (200 aa) |
| | FEN1-2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (308 aa) |
| | EXD3 | Exonuclease 3'-5' domain containing 3. (878 aa) |
| | CPSF3 | Cleavage and polyadenylation specific factor 3. (684 aa) |
| | CNOT2 | CCR4-NOT transcription complex subunit 2. (550 aa) |
| | ENSPPAP00000040043 | CPSF_A domain-containing protein. (263 aa) |
| | DNASE1L3 | Deoxyribonuclease; Belongs to the DNase I family. (305 aa) |
| | ERI3 | ERI1 exoribonuclease family member 3. (337 aa) |
| | ENSPPAP00000040354 | Uncharacterized protein. (241 aa) |
| | NOCT | Nocturnin. (394 aa) |
| | ENSPPAP00000040497 | Uncharacterized protein. (255 aa) |
| | BOP1 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (712 aa) |
| | SND1 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa) |
| | POLG | DNA polymerase gamma, catalytic subunit. (1234 aa) |
| | DCP1A | Decapping mRNA 1A. (582 aa) |
| | EME1 | Essential meiotic structure-specific endonuclease 1. (571 aa) |
| | SMG6 | SMG6 nonsense mediated mRNA decay factor. (1419 aa) |
| | TOE1 | Target of EGR1, exonuclease. (523 aa) |
| | CPSF4 | Cleavage and polyadenylation specific factor 4. (269 aa) |
| | RPS21 | Uncharacterized protein. (90 aa) |
| | EXOSC7 | Exosome component 7. (291 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (297 aa) |
| | CNOT8 | CCR4-NOT transcription complex subunit 8. (292 aa) |
| | DCLRE1A | DNA cross-link repair 1A. (1040 aa) |
| | POP5 | Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (163 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa) |
| | RPP30 | Ribonuclease P/MRP subunit p30. (318 aa) |
| | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (226 aa) |
| | EXOSC9 | Exosome component 9. (456 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa) |
| | ABT1 | Activator of basal transcription 1. (272 aa) |
| | AZGP1 | Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. (298 aa) |
| | TATDN3 | TatD DNase domain containing 3. (274 aa) |
| | MBD4 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (574 aa) |
| | TSR1 | TSR1 ribosome maturation factor. (804 aa) |
| | ENSPPAP00000026192 | Uncharacterized protein. (86 aa) |
| | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa) |
| | SPO11 | SPO11 initiator of meiotic double stranded breaks. (396 aa) |
| | ENDOD1 | Endonuclease domain containing 1. (500 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) |
| | EME2 | Essential meiotic structure-specific endonuclease subunit 2. (378 aa) |
| | EXOSC4 | Exosome component 4. (245 aa) |
| | APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (518 aa) |
| | REXO1 | RNA exonuclease 1 homolog. (1207 aa) |
| | ENSPPAP00000025066 | Uncharacterized protein. (183 aa) |
| | RAD51C | RAD51 paralog C. (376 aa) |
| | DNASE1 | Deoxyribonuclease; Belongs to the DNase I family. (282 aa) |
| | TSEN2 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (464 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1922 aa) |
| | REXO5 | RNA exonuclease 5. (774 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (692 aa) |
| | N4BP1 | NEDD4 binding protein 1. (896 aa) |
| | EXOSC2 | Exosome component 2. (293 aa) |
| | PDE12 | Phosphodiesterase 12. (608 aa) |
| | ENDOV | Endonuclease V. (309 aa) |
| | ENSPPAP00000022929 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (392 aa) |
| | PXDNL | Peroxidasin like. (1441 aa) |
| | NOL9 | Nucleolar protein 9. (702 aa) |
| | KHNYN | KH and NYN domain containing. (678 aa) |
| | ZNRD1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa) |
| | HAUS7 | HAUS augmin like complex subunit 7. (381 aa) |
| | ENSPPAP00000022108 | HORMA domain-containing protein. (363 aa) |
| | ENSPPAP00000022078 | Endo/exonuclease/phosphatase domain-containing protein. (470 aa) |
| | RNASEH1 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (286 aa) |
| | LAS1L | LAS1 like, ribosome biogenesis factor. (731 aa) |
| | DNASE2 | Deoxyribonuclease 2, lysosomal. (360 aa) |
| | UBXN8 | UBX domain protein 8. (298 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa) |
| | ENSPPAP00000020965 | KH type-2 domain-containing protein. (250 aa) |
| | APLF | Aprataxin and PNKP like factor. (511 aa) |
| | C11orf80 | Chromosome 11 open reading frame 80. (572 aa) |
| | XRN2 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa) |
| | PIWIL2 | Uncharacterized protein; Belongs to the argonaute family. (974 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) |
| | RNASE6 | Ribonuclease A family member k6; Belongs to the pancreatic ribonuclease family. (150 aa) |
| | ENSPPAP00000020211 | 40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (76 aa) |
| | RNASE7 | Ribonuclease A family member 7; Belongs to the pancreatic ribonuclease family. (156 aa) |
| | N4BP2 | NEDD4 binding protein 2. (1770 aa) |
| | RNASE2 | Ribonuclease A family member 2; Belongs to the pancreatic ribonuclease family. (161 aa) |
| | RNASE4 | Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (147 aa) |
| | RNASE12 | Ribonuclease A family member 12 (inactive); Belongs to the pancreatic ribonuclease family. (147 aa) |
| | TSN | Translin. (228 aa) |
| | EXOG | Exo/endonuclease G. (368 aa) |
| | ANG | Angiogenin; Belongs to the pancreatic ribonuclease family. (147 aa) |
| | EDC4 | Enhancer of mRNA decapping 4. (1401 aa) |
| | ENSPPAP00000018916 | Uncharacterized protein. (305 aa) |
| | ERI1 | Exoribonuclease 1. (345 aa) |
| | MRPL44 | Mitochondrial ribosomal protein L44. (332 aa) |
| | TATDN1 | TatD DNase domain containing 1. (333 aa) |
| | MEIOB | Uncharacterized protein. (344 aa) |
| | ENSPPAP00000018281 | Uncharacterized protein. (303 aa) |
| | CNOT6 | CCR4-NOT transcription complex subunit 6. (557 aa) |
| | ENSPPAP00000018238 | Uncharacterized protein. (302 aa) |
| | ENSPPAP00000018221 | RRM domain-containing protein. (302 aa) |
| | ENSPPAP00000018027 | Uncharacterized protein. (238 aa) |
| | DIS3L2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (889 aa) |
| | AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | PIWIL3 | Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family. (887 aa) |
| | ENSPPAP00000017700 | Uncharacterized protein. (277 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa) |
| | DCPS | Decapping enzyme, scavenger. (337 aa) |
| | ENSPPAP00000017476 | Uncharacterized protein. (263 aa) |
| | CSTF2 | Cleavage stimulation factor subunit 2. (597 aa) |
| | AGO4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | RNASET2 | Uncharacterized protein. (294 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (949 aa) |
| | NUDT16 | Nudix hydrolase 16. (227 aa) |
| | DCP1B | Decapping mRNA 1B. (621 aa) |
| | PARN | Poly(A)-specific ribonuclease. (639 aa) |
| | ENSPPAP00000016729 | Ribosomal_S3_C domain-containing protein. (100 aa) |
| | ENSPPAP00000016638 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (612 aa) |
| | DCLRE1B | DNA cross-link repair 1B. (532 aa) |
| | ANGEL2 | Angel homolog 2. (544 aa) |
| | DBR1 | Debranching RNA lariats 1. (545 aa) |
| | DNASE2B | Deoxyribonuclease 2 beta. (361 aa) |
| | ISG20L2 | Interferon stimulated exonuclease gene 20 like 2. (352 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (977 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (391 aa) |
| | TSEN15 | tRNA splicing endonuclease subunit 15. (175 aa) |
| | YBEY | YbeY metalloendoribonuclease. (167 aa) |
| | SLFNL1 | Schlafen like 1. (407 aa) |
| | ENSPPAP00000015279 | Sen15 domain-containing protein. (142 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1832 aa) |
| | TSNAX | Translin associated factor X. (290 aa) |
| | APTX | Aprataxin. (354 aa) |
| | ENSPPAP00000014227 | Uncharacterized protein. (210 aa) |
| | CNOT6L | CCR4-NOT transcription complex subunit 6 like. (548 aa) |
| | POLD1 | DNA polymerase. (1133 aa) |
| | PLD6 | Phospholipase D family member 6. (252 aa) |
| | EXOSC3 | Exosome component 3. (275 aa) |
| | RIDA | Reactive intermediate imine deaminase A homolog. (137 aa) |
