(9 nodes) Renal tubular secretion network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UMOD	Uromodulin. (681 aa)
	ABCG2	ATP binding cassette subfamily G member 2 (Junior blood group). (655 aa)
	ATP6V1B1	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
	SLC22A20P	MFS domain-containing protein. (557 aa)
	SLC22A12	Solute carrier family 22 member 12. (550 aa)
	ATP6V0A4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (782 aa)
	SLC22A6	Solute carrier family 22 member 6. (550 aa)
	MLLT6	MLLT6, PHD finger containing. (1056 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG2	SLC22A12	ENSPPAP00000006058	ENSPPAP00000016650	ATP binding cassette subfamily G member 2 (Junior blood group).	Solute carrier family 22 member 12.	0.695
ABCG2	SLC22A6	ENSPPAP00000006058	ENSPPAP00000025411	ATP binding cassette subfamily G member 2 (Junior blood group).	Solute carrier family 22 member 6.	0.537
ATP6V0A4	ATP6V1B1	ENSPPAP00000018029	ENSPPAP00000006998	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.985
ATP6V1B1	ATP6V0A4	ENSPPAP00000006998	ENSPPAP00000018029	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.985
SLC22A12	ABCG2	ENSPPAP00000016650	ENSPPAP00000006058	Solute carrier family 22 member 12.	ATP binding cassette subfamily G member 2 (Junior blood group).	0.695
SLC22A12	UMOD	ENSPPAP00000016650	ENSPPAP00000029629	Solute carrier family 22 member 12.	Uromodulin.	0.436
SLC22A6	ABCG2	ENSPPAP00000025411	ENSPPAP00000006058	Solute carrier family 22 member 6.	ATP binding cassette subfamily G member 2 (Junior blood group).	0.537
UMOD	SLC22A12	ENSPPAP00000029629	ENSPPAP00000016650	Uromodulin.	Solute carrier family 22 member 12.	0.436