(5 nodes) R2TP complex network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUVBL2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
	RUVBL1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	PIH1D2	PIH1 domain containing 2. (315 aa)
	PIH1D1	PIH1 domain containing 1. (321 aa)
	RPAP3	RNA polymerase II associated protein 3. (665 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PIH1D1	RPAP3	ENSPPAP00000024786	ENSPPAP00000020519	PIH1 domain containing 1.	RNA polymerase II associated protein 3.	0.999
PIH1D1	RUVBL1	ENSPPAP00000024786	ENSPPAP00000034521	PIH1 domain containing 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.989
PIH1D1	RUVBL2	ENSPPAP00000024786	ENSPPAP00000030733	PIH1 domain containing 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.989
PIH1D2	RPAP3	ENSPPAP00000041389	ENSPPAP00000020519	PIH1 domain containing 2.	RNA polymerase II associated protein 3.	0.792
PIH1D2	RUVBL1	ENSPPAP00000041389	ENSPPAP00000034521	PIH1 domain containing 2.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.903
PIH1D2	RUVBL2	ENSPPAP00000041389	ENSPPAP00000030733	PIH1 domain containing 2.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.903
RPAP3	PIH1D1	ENSPPAP00000020519	ENSPPAP00000024786	RNA polymerase II associated protein 3.	PIH1 domain containing 1.	0.999
RPAP3	PIH1D2	ENSPPAP00000020519	ENSPPAP00000041389	RNA polymerase II associated protein 3.	PIH1 domain containing 2.	0.792
RPAP3	RUVBL1	ENSPPAP00000020519	ENSPPAP00000034521	RNA polymerase II associated protein 3.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.999
RPAP3	RUVBL2	ENSPPAP00000020519	ENSPPAP00000030733	RNA polymerase II associated protein 3.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.998
RUVBL1	PIH1D1	ENSPPAP00000034521	ENSPPAP00000024786	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	PIH1 domain containing 1.	0.989
RUVBL1	PIH1D2	ENSPPAP00000034521	ENSPPAP00000041389	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	PIH1 domain containing 2.	0.903
RUVBL1	RPAP3	ENSPPAP00000034521	ENSPPAP00000020519	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	RNA polymerase II associated protein 3.	0.999
RUVBL1	RUVBL2	ENSPPAP00000034521	ENSPPAP00000030733	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.999
RUVBL2	PIH1D1	ENSPPAP00000030733	ENSPPAP00000024786	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	PIH1 domain containing 1.	0.989
RUVBL2	PIH1D2	ENSPPAP00000030733	ENSPPAP00000041389	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	PIH1 domain containing 2.	0.903
RUVBL2	RPAP3	ENSPPAP00000030733	ENSPPAP00000020519	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	RNA polymerase II associated protein 3.	0.998
RUVBL2	RUVBL1	ENSPPAP00000030733	ENSPPAP00000034521	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.999