STRINGSTRING
GRM2 GRM2 SLC1A1 SLC1A1 ADGRG1 ADGRG1 GRM5 GRM5 NFASC NFASC GPR161 GPR161 PINK1 PINK1 SCN7A SCN7A SLC1A2 SLC1A2 KCNK2 KCNK2 AQP4 AQP4 LOC100979570 LOC100979570 LCP1 LCP1 SLC4A8 SLC4A8 ERMN ERMN SYT4 SYT4 WASF3 WASF3 ATP1B2 ATP1B2 FYN FYN SIRT2 SIRT2 CRB1 CRB1 GRM3 GRM3 ITGB1 ITGB1 ABCA7 ABCA7 AIF1 AIF1 SLC7A11 SLC7A11 SLC2A13 SLC2A13 CNGA3 CNGA3 MT3 MT3 EIF2S1 EIF2S1 SLC17A8 SLC17A8 FMR1 FMR1 GLUL GLUL GFAP GFAP DMD DMD TMEM50A TMEM50A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRM2Glutamate metabotropic receptor 2. (872 aa)
SLC1A1Amino acid transporter. (524 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (687 aa)
GRM5Glutamate metabotropic receptor 5. (1195 aa)
NFASCNeurofascin. (1338 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (546 aa)
PINK1PTEN induced kinase 1. (554 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1682 aa)
SLC1A2Amino acid transporter. (574 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
LOC100979570Glutamine synthetase. (366 aa)
LCP1Lymphocyte cytosolic protein 1. (630 aa)
SLC4A8Anion exchange protein. (1093 aa)
ERMNErmin. (285 aa)
SYT4Synaptotagmin 4. (425 aa)
WASF3WASP family member 3. (502 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (267 aa)
FYNTyrosine-protein kinase. (537 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ABCA7ATP binding cassette subfamily A member 7. (2146 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
SLC7A11Solute carrier family 7 member 11. (515 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (587 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (694 aa)
MT3Uncharacterized protein; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
FMR1Fragile X mental retardation 1. (615 aa)
GLULGlutamine synthetase. (373 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)
DMDDystrophin. (3517 aa)
TMEM50AUncharacterized protein. (157 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.