STRINGSTRING
SLC5A6 SLC5A6 LOC100993107 LOC100993107 LRRC8A LRRC8A SLC9A1 SLC9A1 CACNA1D CACNA1D PAWR PAWR SLC12A8 SLC12A8 SLC47A1 SLC47A1 SLC6A9 SLC6A9 SLC12A5 SLC12A5 NTSR1 NTSR1 TRPV3 TRPV3 GRM1 GRM1 SLC24A1 SLC24A1 SLC1A6 SLC1A6 SLC6A1 SLC6A1 ENSPPAP00000040216 ENSPPAP00000040216 SLC39A5 SLC39A5 SLC39A10 SLC39A10 GFAP GFAP SLC27A1 SLC27A1 SLC6A6 SLC6A6 KCNK9 KCNK9 LRP2 LRP2 TSPO2 TSPO2 HFE HFE SLC5A1 SLC5A1 CACNA1B CACNA1B SLC5A2 SLC5A2 SLC24A4 SLC24A4 ATP2B4 ATP2B4 SLC1A4 SLC1A4 SLC27A5 SLC27A5 CNGA3 CNGA3 SLC22A4 SLC22A4 SLC1A5 SLC1A5 TRPV2 TRPV2 KCNJ8 KCNJ8 CACNA1S CACNA1S SLC9A9 SLC9A9 TRPV6 TRPV6 ENSPPAP00000034705 ENSPPAP00000034705 LOC100995958 LOC100995958 CLN8 CLN8 SLC9A5 SLC9A5 ATP1A1 ATP1A1 SCNN1D SCNN1D ATP1A3 ATP1A3 ENSPPAP00000033087 ENSPPAP00000033087 SLC7A11 SLC7A11 SLC9C1 SLC9C1 SLC15A4 SLC15A4 ATP1B3 ATP1B3 SLC36A4 SLC36A4 PSEN1 PSEN1 SLC6A13 SLC6A13 SLC16A2 SLC16A2 PKD1L2 PKD1L2 SLC15A1 SLC15A1 SLC39A12 SLC39A12 HCN2 HCN2 KCNJ10 KCNJ10 SLC12A3 SLC12A3 SLC9A6 SLC9A6 SLC15A2 SLC15A2 SLC7A1 SLC7A1 ATP4A ATP4A SLC39A4 SLC39A4 LRRC8E LRRC8E TRPM2 TRPM2 SLC9A7 SLC9A7 ATP1B1 ATP1B1 SLC39A8 SLC39A8 SLC9A2 SLC9A2 ATP1B2 ATP1B2 KCNQ1 KCNQ1 SLC36A1 SLC36A1 SLC12A4 SLC12A4 KCNJ5 KCNJ5 LRRC8C LRRC8C KCNJ9 KCNJ9 SCNN1A SCNN1A ABCC9 ABCC9 ATP1A2 ATP1A2 SLC9A4 SLC9A4 SLC6A20 SLC6A20 SLC12A6 SLC12A6 SLC2A1 SLC2A1 SCNN1B SCNN1B ARL6IP5 ARL6IP5 HCN4 HCN4 SLC1A3 SLC1A3 SLC9A3 SLC9A3 KCNJ6 KCNJ6 KCNJ15 KCNJ15 TRPM4 TRPM4 TRPM1 TRPM1 SLC6A5 SLC6A5 KCNJ16 KCNJ16 CACNA1C CACNA1C SLC34A1 SLC34A1 TRPV5 TRPV5 SLC1A2 SLC1A2 FOLR1 FOLR1 ENSPPAP00000014388 ENSPPAP00000014388 KCNJ13 KCNJ13 SLC8A2 SLC8A2 TRPV4 TRPV4 SLC12A7 SLC12A7 SLC7A8 SLC7A8 SLC46A1 SLC46A1 KCNJ14 KCNJ14 SLC9C2 SLC9C2 ATP1A4 ATP1A4 SLC39A6 SLC39A6 CACNA1E CACNA1E SLC6A14 SLC6A14 ATP12A ATP12A SLC19A1 SLC19A1 CACNA1F CACNA1F SLC1A1 SLC1A1 SLC12A2 SLC12A2 SCNN1G SCNN1G SLC7A5 SLC7A5 FAM155B FAM155B ABCC8 ABCC8 CACNA2D1 CACNA2D1 LOC103786316 LOC103786316 SLC2A5 SLC2A5 SLC15A3 SLC15A3 KCNJ4 KCNJ4 SLC3A2 SLC3A2 SLC2A10 SLC2A10 SLC8A3 SLC8A3 CACNA1A CACNA1A SLC2A3 SLC2A3 SLC5A3 SLC5A3 FAM155A FAM155A KCNJ11 KCNJ11 SLC7A2 SLC7A2 KCNK5 KCNK5 KCNJ3 KCNJ3 SLC9A3R1 SLC9A3R1 SLC24A2 SLC24A2 STEAP2 STEAP2 SLC22A2 SLC22A2 KCNJ1 KCNJ1 ATP4B ATP4B KCNJ2 KCNJ2 TRPV1 TRPV1 CD36 CD36 KCNE2 KCNE2 SLC12A1 SLC12A1 SLC39A14 SLC39A14 SLC8A1 SLC8A1 SLC7A3 SLC7A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC5A6Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (636 aa)
LOC100993107Folate_rec domain-containing protein. (237 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
PAWRPro-apoptotic WT1 regulator. (320 aa)
SLC12A8Solute carrier family 12 member 8. (714 aa)
SLC47A1Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (586 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (706 aa)
SLC12A5Solute carrier family 12 member 5. (1139 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (405 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
GRM1Glutamate metabotropic receptor 1. (1194 aa)
SLC24A1Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1094 aa)
SLC1A6Amino acid transporter. (564 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
ENSPPAP00000040216MFS domain-containing protein. (228 aa)
SLC39A5Solute carrier family 39 member 5. (540 aa)
SLC39A10Solute carrier family 39 member 10. (831 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)
SLC27A1Solute carrier family 27 member 1. (646 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
KCNK9Potassium channel subfamily K member. (375 aa)
LRP2LDL receptor related protein 2. (4641 aa)
TSPO2Translocator protein 2. (170 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (664 aa)
CACNA1BUncharacterized protein. (491 aa)
SLC5A2Solute carrier family 5 member 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (679 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
SLC1A4Amino acid transporter. (523 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (694 aa)
SLC22A4Solute carrier family 22 member 4. (551 aa)
SLC1A5Amino acid transporter. (526 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (534 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (765 aa)
ENSPPAP00000034705Na_H_Exchanger domain-containing protein. (666 aa)
LOC100995958Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (268 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (286 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (894 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
SCNN1DSodium channel epithelial 1 delta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (764 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (857 aa)
ENSPPAP00000033087Uncharacterized protein. (751 aa)
SLC7A11Solute carrier family 7 member 11. (515 aa)
SLC9C1Solute carrier family 9 member C1. (1174 aa)
SLC15A4Uncharacterized protein. (395 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (242 aa)
SLC36A4Solute carrier family 36 member 4. (509 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
SLC6A13Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (602 aa)
SLC16A2Solute carrier family 16 member 2. (611 aa)
PKD1L2Uncharacterized protein. (984 aa)
SLC15A1Solute carrier family 15 member 1. (708 aa)
SLC39A12Solute carrier family 39 member 12. (691 aa)
HCN2Cyclic nucleotide-binding domain-containing protein. (518 aa)
KCNJ10IRK domain-containing protein. (207 aa)
SLC12A3Solute carrier family 12 member 3. (1021 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (696 aa)
SLC15A2Solute carrier family 15 member 2. (729 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
SLC39A4Solute carrier family 39 member 4. (649 aa)
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (796 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (671 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
SLC39A8Solute carrier family 39 member 8. (444 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (811 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (267 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
SLC36A1Solute carrier family 36 member 1. (476 aa)
SLC12A4Solute carrier family 12 member 4. (1083 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
LRRC8CLeucine rich repeat containing 8 VRAC subunit C. (773 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
SCNN1AUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (511 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (798 aa)
SLC6A20Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (592 aa)
SLC12A6Solute carrier family 12 member 6. (1151 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (685 aa)
ARL6IP5PRA1 family protein. (188 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1030 aa)
SLC1A3Amino acid transporter. (542 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (867 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (375 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1138 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1642 aa)
SLC6A5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (797 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (457 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
SLC34A1Solute carrier family 34 member 1. (641 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (732 aa)
SLC1A2Amino acid transporter. (574 aa)
FOLR1Folate receptor alpha. (257 aa)
ENSPPAP00000014388Uncharacterized protein. (165 aa)
KCNJ13Potassium voltage-gated channel subfamily J member 13. (360 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (908 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
SLC12A7Solute carrier family 12 member 7. (1051 aa)
SLC7A8Solute carrier family 7 member 8. (535 aa)
SLC46A1Solute carrier family 46 member 1. (417 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (436 aa)
SLC9C2Solute carrier family 9 member C2 (putative). (1124 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
SLC39A6Solute carrier family 39 member 6. (755 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2298 aa)
SLC6A14Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (642 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (989 aa)
SLC19A1Solute carrier family 19 member 1. (591 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1974 aa)
SLC1A1Amino acid transporter. (524 aa)
SLC12A2Solute carrier family 12 member 2. (1091 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (649 aa)
SLC7A5Uncharacterized protein. (241 aa)
FAM155BUncharacterized protein. (348 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
LOC103786316FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
SLC2A5Solute carrier family 2 member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (501 aa)
SLC15A3Solute carrier family 15 member 3. (556 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (445 aa)
SLC3A2Solute carrier family 3 member 2. (631 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa)
SLC8A3Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (210 aa)
CACNA1ACalcium voltage-gated channel subunit alpha1 A. (2359 aa)
SLC2A3Solute carrier family 2 member 3; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (433 aa)
SLC5A3Solute carrier family 5 member 3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (718 aa)
FAM155AFamily with sequence similarity 155 member A. (457 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
SLC7A2Solute carrier family 7 member 2. (696 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
KCNJ3Uncharacterized protein. (308 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (661 aa)
STEAP2STEAP2 metalloreductase. (490 aa)
SLC22A2Solute carrier family 22 member 2. (555 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (391 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (291 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
SLC7A3Solute carrier family 7 member 3. (619 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (22%) [HD]