(20 nodes) Postsynaptic cytosol network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPPAP00000028140	Uncharacterized protein; Belongs to the heat shock protein 70 family. (501 aa)
	ENSPPAP00000005060	Uncharacterized protein; Belongs to the DEAD box helicase family. (371 aa)
	BAIAP2	BAI1 associated protein 2. (549 aa)
	ENSPPAP00000008364	Peptidyl-prolyl cis-trans isomerase. (155 aa)
	FBXO45	F-box protein 45. (247 aa)
	HTT	Huntingtin. (3053 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	ENSPPAP00000015368	Uncharacterized protein; Belongs to the heat shock protein 70 family. (630 aa)
	ENSPPAP00000016619	Uncharacterized protein; Belongs to the heat shock protein 70 family. (564 aa)
	HOMER1	Homer scaffold protein 1. (358 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (145 aa)
	DAG1	Dystroglycan 1. (895 aa)
	ENSPPAP00000026880	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (222 aa)
	DBN1	Drebrin 1. (677 aa)
	LOC100981595	Uncharacterized protein. (400 aa)
	ENSPPAP00000032433	Uncharacterized protein. (64 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
	HSPA8	Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
	CALB1	Calbindin 1. (261 aa)
	EIF4E	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (246 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALB1	PRKCG	ENSPPAP00000039772	ENSPPAP00000013387	Calbindin 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.522
DBN1	HOMER1	ENSPPAP00000027801	ENSPPAP00000018267	Drebrin 1.	Homer scaffold protein 1.	0.529
EIF4E	ENSPPAP00000005060	ENSPPAP00000042127	ENSPPAP00000005060	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.898
ENSPPAP00000005060	EIF4E	ENSPPAP00000005060	ENSPPAP00000042127	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.898
ENSPPAP00000005060	ENSPPAP00000026880	ENSPPAP00000005060	ENSPPAP00000026880	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.837
ENSPPAP00000005060	ENSPPAP00000032433	ENSPPAP00000005060	ENSPPAP00000032433	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.662
ENSPPAP00000015368	HTT	ENSPPAP00000015368	ENSPPAP00000011723	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Huntingtin.	0.584
ENSPPAP00000016619	HTT	ENSPPAP00000016619	ENSPPAP00000011723	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Huntingtin.	0.584
ENSPPAP00000026880	ENSPPAP00000005060	ENSPPAP00000026880	ENSPPAP00000005060	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.837
ENSPPAP00000028140	HTT	ENSPPAP00000028140	ENSPPAP00000011723	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Huntingtin.	0.584
ENSPPAP00000032433	ENSPPAP00000005060	ENSPPAP00000032433	ENSPPAP00000005060	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.662
HOMER1	DBN1	ENSPPAP00000018267	ENSPPAP00000027801	Homer scaffold protein 1.	Drebrin 1.	0.529
HSPA8	HTT	ENSPPAP00000036545	ENSPPAP00000011723	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Huntingtin.	0.584
HTT	ENSPPAP00000015368	ENSPPAP00000011723	ENSPPAP00000015368	Huntingtin.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.584
HTT	ENSPPAP00000016619	ENSPPAP00000011723	ENSPPAP00000016619	Huntingtin.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.584
HTT	ENSPPAP00000028140	ENSPPAP00000011723	ENSPPAP00000028140	Huntingtin.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.584
HTT	HSPA8	ENSPPAP00000011723	ENSPPAP00000036545	Huntingtin.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.584
HTT	LOC100981595	ENSPPAP00000011723	ENSPPAP00000028053	Huntingtin.	Uncharacterized protein.	0.584
LOC100981595	HTT	ENSPPAP00000028053	ENSPPAP00000011723	Uncharacterized protein.	Huntingtin.	0.584
PRKCG	CALB1	ENSPPAP00000013387	ENSPPAP00000039772	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Calbindin 1.	0.522