STRINGSTRING
MAPKAPK5 MAPKAPK5 ENSPPAP00000043220 ENSPPAP00000043220 PKIB PKIB TNKS2 TNKS2 MAP2K7 MAP2K7 MAPK3 MAPK3 MAP3K4 MAP3K4 RTEL1 RTEL1 MAPK15 MAPK15 HNRNPD HNRNPD NEK2 NEK2 NEK7 NEK7 TNKS TNKS AURKB AURKB PRKCQ PRKCQ MAPK1 MAPK1 PNKP PNKP NABP2 NABP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPKAPK5MAPK activated protein kinase 5. (490 aa)
ENSPPAP00000043220Uncharacterized protein. (46 aa)
PKIBcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (85 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (408 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (311 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1597 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1318 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (349 aa)
NEK2NIMA related kinase 2. (445 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (758 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (521 aa)
NABP2Nucleic acid binding protein 2. (211 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.