(52 nodes) Negative regulation of leukocyte apoptotic process network (Pan paniscus)

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Your Input:
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	CCL5	C-C motif chemokine. (91 aa)
	RAG1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1040 aa)
	ARG2	Arginase. (354 aa)
	SLC39A10	Solute carrier family 39 member 10. (831 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	DOCK8	Dedicator of cytokinesis 8; Belongs to the DOCK family. (2099 aa)
	JAK3	Tyrosine-protein kinase. (1090 aa)
	CXCL12	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	PTCRA	Pre T cell antigen receptor alpha. (281 aa)
	SLC46A2	Solute carrier family 46 member 2. (475 aa)
	TSC22D3	TSC22 domain family member 3. (200 aa)
	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (340 aa)
	IL7R	Interleukin 7 receptor. (459 aa)
	BCL10	CARD domain-containing protein. (316 aa)
	FOXP1	Forkhead box P1. (676 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	BCL3	BCL3 transcription coactivator. (383 aa)
	AXL	AXL receptor tyrosine kinase. (894 aa)
	CD74	CD74 molecule. (296 aa)
	CD27	CD27 molecule. (260 aa)
	ORMDL3	ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
	NOC2L	NOC2 like nucleolar associated transcriptional repressor. (712 aa)
	FADD	Death domain-containing protein. (144 aa)
	ITPKB	Kinase; Belongs to the inositol phosphokinase (IPK) family. (946 aa)
	ENSPPAP00000020322	Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (320 aa)
	CCL19	C-C motif chemokine. (98 aa)
	ST6GAL1	ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa)
	MIF	Macrophage migration inhibitory factor. (115 aa)
	BCL2	BCL2 apoptosis regulator. (193 aa)
	KITLG	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
	SELENOS	Uncharacterized protein. (218 aa)
	GAS6	Growth arrest specific 6. (679 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
	MERTK	MER proto-oncogene, tyrosine kinase. (966 aa)
	IRF7	Interferon regulatory factor 7. (516 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
	IDO1	Indoleamine 2,3-dioxygenase 1. (403 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	KIFAP3	Kinesin associated protein 3. (792 aa)
	BMP4	TGF_BETA_2 domain-containing protein. (402 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (758 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)
	IL18	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
	BCL11B	Uncharacterized protein. (459 aa)
	EFNA1	Ephrin A1; Belongs to the ephrin family. (205 aa)
	RORC	RAR related orphan receptor C. (525 aa)
	ADA	Adenosine deaminase. (412 aa)
	HCLS1	Hematopoietic cell-specific Lyn substrate 1. (484 aa)
	CCL21	C-C motif chemokine ligand 21. (134 aa)
	BCL2L1	BCL2 like 1. (233 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	IL2	ENSPPAP00000006331	ENSPPAP00000014571	Adenosine deaminase.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.525
ADA	RAG1	ENSPPAP00000006331	ENSPPAP00000042397	Adenosine deaminase.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.467
ARG2	HIF1A	ENSPPAP00000039767	ENSPPAP00000010904	Arginase.	Hypoxia inducible factor 1 subunit alpha.	0.401
ARG2	IDO1	ENSPPAP00000039767	ENSPPAP00000011852	Arginase.	Indoleamine 2,3-dioxygenase 1.	0.605
ARG2	IL2	ENSPPAP00000039767	ENSPPAP00000014571	Arginase.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.415
AURKB	NOC2L	ENSPPAP00000012246	ENSPPAP00000025116	Aurora kinase B; Belongs to the protein kinase superfamily.	NOC2 like nucleolar associated transcriptional repressor.	0.841
AXL	FADD	ENSPPAP00000029397	ENSPPAP00000023141	AXL receptor tyrosine kinase.	Death domain-containing protein.	0.523
AXL	GAS6	ENSPPAP00000029397	ENSPPAP00000015163	AXL receptor tyrosine kinase.	Growth arrest specific 6.	0.963
BCL10	BCL2	ENSPPAP00000032949	ENSPPAP00000017780	CARD domain-containing protein.	BCL2 apoptosis regulator.	0.590
BCL10	BCL2L1	ENSPPAP00000032949	ENSPPAP00000000019	CARD domain-containing protein.	BCL2 like 1.	0.458
BCL10	BCL3	ENSPPAP00000032949	ENSPPAP00000030188	CARD domain-containing protein.	BCL3 transcription coactivator.	0.414
BCL10	BCL6	ENSPPAP00000032949	ENSPPAP00000011560	CARD domain-containing protein.	BCL6 transcription repressor.	0.481
BCL10	FADD	ENSPPAP00000032949	ENSPPAP00000023141	CARD domain-containing protein.	Death domain-containing protein.	0.549
BCL10	NOD2	ENSPPAP00000032949	ENSPPAP00000040678	CARD domain-containing protein.	Nucleotide binding oligomerization domain containing 2.	0.528
BCL10	PRKCQ	ENSPPAP00000032949	ENSPPAP00000010905	CARD domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.859
BCL11B	BCL6	ENSPPAP00000008260	ENSPPAP00000011560	Uncharacterized protein.	BCL6 transcription repressor.	0.511
BCL2	BCL10	ENSPPAP00000017780	ENSPPAP00000032949	BCL2 apoptosis regulator.	CARD domain-containing protein.	0.590
BCL2	BCL2L1	ENSPPAP00000017780	ENSPPAP00000000019	BCL2 apoptosis regulator.	BCL2 like 1.	0.998
BCL2	BCL3	ENSPPAP00000017780	ENSPPAP00000030188	BCL2 apoptosis regulator.	BCL3 transcription coactivator.	0.494
BCL2	BCL6	ENSPPAP00000017780	ENSPPAP00000011560	BCL2 apoptosis regulator.	BCL6 transcription repressor.	0.750