STRINGSTRING
RIMS4 RIMS4 HTR2A HTR2A P2RY4 P2RY4 CHRM2 CHRM2 GIPC3 GIPC3 LOC100982471 LOC100982471 DRD1 DRD1 P2RX7 P2RX7 DVL1 DVL1 ENSPPAP00000006260 ENSPPAP00000006260 P2RY1 P2RY1 GRIN3A GRIN3A ENSPPAP00000009209 ENSPPAP00000009209 CACNB4 CACNB4 FBXL20 FBXL20 ADORA2B ADORA2B SYN1 SYN1 RAB3GAP1 RAB3GAP1 RAB3A RAB3A SYT1 SYT1 GIT1 GIT1 PRKCG PRKCG DRD2 DRD2 NLGN1 NLGN1 WNT7A WNT7A P2RX1 P2RX1 APBA2 APBA2 VPS18 VPS18 ADORA2A ADORA2A NRXN3 NRXN3 SLC4A8 SLC4A8 CACNB2 CACNB2 SYP SYP DGKI DGKI STXBP5 STXBP5 CHRNA5 CHRNA5 PRKCB PRKCB CDK5 CDK5 SYT4 SYT4 BRAF BRAF STXBP5L STXBP5L ENSPPAP00000026998 ENSPPAP00000026998 SNAPIN SNAPIN SYNPR SYNPR APBA1 APBA1 CALM3 CALM3 BACE1 BACE1 GIPC2 GIPC2 DTNBP1 DTNBP1 ADCY1 ADCY1 RAP1B RAP1B RIMS3 RIMS3 RAP1A RAP1A CASK CASK PREPL PREPL ENSPPAP00000035001 ENSPPAP00000035001 LRRK2 LRRK2 GSK3B GSK3B CSPG5 CSPG5 RAB5A RAB5A GIPC1 GIPC1 FMR1 FMR1 SEPTIN5 SEPTIN5 ATP2A2 ATP2A2 ADRA1A ADRA1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIMS4Regulating synaptic membrane exocytosis 4. (265 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
GIPC3GIPC PDZ domain containing family member 3. (264 aa)
LOC100982471Uncharacterized protein; Belongs to the calmodulin family. (93 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
DVL1Dishevelled segment polarity protein 1. (674 aa)
ENSPPAP00000006260Uncharacterized protein. (99 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1068 aa)
ENSPPAP00000009209Profilin; Belongs to the profilin family. (91 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
FBXL20F-box and leucine rich repeat protein 20. (438 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (357 aa)
SYN1Uncharacterized protein. (538 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (988 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
SYT1Synaptotagmin 1. (422 aa)
GIT1GIT ArfGAP 1. (755 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
NLGN1Neuroligin 1. (823 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
APBA2Amyloid beta precursor protein binding family A member 2. (751 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
NRXN3Neurexin 3. (1664 aa)
SLC4A8Anion exchange protein. (1093 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
SYPSynaptophysin. (313 aa)
DGKIDiacylglycerol kinase. (905 aa)
STXBP5Syntaxin binding protein 5. (1152 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (458 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
SYT4Synaptotagmin 4. (425 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
STXBP5LSyntaxin binding protein 5 like. (1186 aa)
ENSPPAP00000026998Uncharacterized protein. (493 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
SYNPRSynaptoporin. (285 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (791 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
GIPC2GIPC PDZ domain containing family member 2. (319 aa)
DTNBP1Dystrobrevin binding protein 1. (351 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
PREPLProlyl endopeptidase like. (727 aa)
ENSPPAP00000035001Uncharacterized protein. (110 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (562 aa)
RAB5ARAB5A, member RAS oncogene family. (216 aa)
GIPC1GIPC PDZ domain containing family member 1. (332 aa)
FMR1Fragile X mental retardation 1. (615 aa)
SEPTIN5Septin 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (379 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1034 aa)
ADRA1AAdrenoceptor alpha 1A. (495 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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