(16 nodes) NuA4 histone acetyltransferase complex network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100984360	MRG domain-containing protein. (323 aa)
	MRGBP-2	Uncharacterized protein. (146 aa)
	MBTD1	Mbt domain containing 1. (630 aa)
	MEAF6	MYST/Esa1 associated factor 6. (179 aa)
	ING3	Inhibitor of growth protein. (418 aa)
	ACTL6A	Actin like 6A; Belongs to the actin family. (430 aa)
	BRD8	Bromodomain containing 8. (1235 aa)
	YEATS4	YEATS domain containing 4. (227 aa)
	ENSPPAP00000018351	MRG domain-containing protein. (244 aa)
	EPC1	Enhancer of polycomb homolog. (836 aa)
	VPS72	Vacuolar protein sorting 72 homolog. (364 aa)
	MRGBP	Uncharacterized protein. (75 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	EPC2	Enhancer of polycomb homolog. (807 aa)
	MORF4L1	MRG domain-containing protein. (335 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTL6A	BRD8	ENSPPAP00000017586	ENSPPAP00000018002	Actin like 6A; Belongs to the actin family.	Bromodomain containing 8.	0.973
ACTL6A	ENSPPAP00000018351	ENSPPAP00000017586	ENSPPAP00000018351	Actin like 6A; Belongs to the actin family.	MRG domain-containing protein.	0.818
ACTL6A	EPC1	ENSPPAP00000017586	ENSPPAP00000018905	Actin like 6A; Belongs to the actin family.	Enhancer of polycomb homolog.	0.966
ACTL6A	EPC2	ENSPPAP00000017586	ENSPPAP00000034547	Actin like 6A; Belongs to the actin family.	Enhancer of polycomb homolog.	0.895
ACTL6A	ING3	ENSPPAP00000017586	ENSPPAP00000011672	Actin like 6A; Belongs to the actin family.	Inhibitor of growth protein.	0.964
ACTL6A	KAT5	ENSPPAP00000017586	ENSPPAP00000038731	Actin like 6A; Belongs to the actin family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.991
ACTL6A	LOC100984360	ENSPPAP00000017586	ENSPPAP00000002292	Actin like 6A; Belongs to the actin family.	MRG domain-containing protein.	0.898
ACTL6A	MBTD1	ENSPPAP00000017586	ENSPPAP00000008791	Actin like 6A; Belongs to the actin family.	Mbt domain containing 1.	0.451
ACTL6A	MEAF6	ENSPPAP00000017586	ENSPPAP00000010261	Actin like 6A; Belongs to the actin family.	MYST/Esa1 associated factor 6.	0.980
ACTL6A	MORF4L1	ENSPPAP00000017586	ENSPPAP00000035596	Actin like 6A; Belongs to the actin family.	MRG domain-containing protein.	0.898
ACTL6A	MRGBP	ENSPPAP00000017586	ENSPPAP00000032827	Actin like 6A; Belongs to the actin family.	Uncharacterized protein.	0.921
ACTL6A	MRGBP-2	ENSPPAP00000017586	ENSPPAP00000002728	Actin like 6A; Belongs to the actin family.	Uncharacterized protein.	0.921
ACTL6A	VPS72	ENSPPAP00000017586	ENSPPAP00000029135	Actin like 6A; Belongs to the actin family.	Vacuolar protein sorting 72 homolog.	0.964
ACTL6A	YEATS4	ENSPPAP00000017586	ENSPPAP00000018316	Actin like 6A; Belongs to the actin family.	YEATS domain containing 4.	0.975
BRD8	ACTL6A	ENSPPAP00000018002	ENSPPAP00000017586	Bromodomain containing 8.	Actin like 6A; Belongs to the actin family.	0.973
BRD8	ENSPPAP00000018351	ENSPPAP00000018002	ENSPPAP00000018351	Bromodomain containing 8.	MRG domain-containing protein.	0.908
BRD8	EPC1	ENSPPAP00000018002	ENSPPAP00000018905	Bromodomain containing 8.	Enhancer of polycomb homolog.	0.925
BRD8	EPC2	ENSPPAP00000018002	ENSPPAP00000034547	Bromodomain containing 8.	Enhancer of polycomb homolog.	0.912
BRD8	ING3	ENSPPAP00000018002	ENSPPAP00000011672	Bromodomain containing 8.	Inhibitor of growth protein.	0.988
BRD8	KAT5	ENSPPAP00000018002	ENSPPAP00000038731	Bromodomain containing 8.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.993