STRINGSTRING
COL15A1 COL15A1 TGFB3 TGFB3 COL8A2 COL8A2 COL3A1 COL3A1 MFAP4 MFAP4 COLQ COLQ ECM1 ECM1 COL4A2 COL4A2 TINAG TINAG AGRN AGRN OTOL1 OTOL1 LOC100970223 LOC100970223 ZG16 ZG16 MMRN2 MMRN2 APLP1 APLP1 MATN3 MATN3 LAMA1 LAMA1 COL4A3 COL4A3 COL5A2 COL5A2 COL7A1 COL7A1 USH2A USH2A COL5A3 COL5A3 SERPINE1 SERPINE1 ANXA2 ANXA2 LAMA5 LAMA5 IL13 IL13 TIMP2 TIMP2 TGFB2 TGFB2 CD151 CD151 ANXA5 ANXA5 C1QTNF9B C1QTNF9B IL2 IL2 WNT2 WNT2 COL12A1 COL12A1 VIT VIT PMP22 PMP22 NTN1 NTN1 COL26A1 COL26A1 LEFTY2 LEFTY2 KAZALD1 KAZALD1 COL6A2 COL6A2 IMPG1 IMPG1 LAMA2 LAMA2 POSTN POSTN COL10A1 COL10A1 MMP8 MMP8 LTBP4 LTBP4 NTN4 NTN4 COL11A1 COL11A1 LAMC2 LAMC2 LOX LOX COL4A5 COL4A5 TIMP3 TIMP3 MATN4 MATN4 ENSPPAP00000025633 ENSPPAP00000025633 FGFBP3 FGFBP3 CCN1 CCN1 TRIM33 TRIM33 NTNG2 NTNG2 ERBIN ERBIN ANGPT1 ANGPT1 LTBP3 LTBP3 TIMP1 TIMP1 PAQR4 PAQR4 MORC3 MORC3 NDP NDP LAMB1 LAMB1 IL17A IL17A EFEMP2 EFEMP2 LAMB3 LAMB3 ENSPPAP00000010225 ENSPPAP00000010225 FOXP3 FOXP3 EMILIN1 EMILIN1 AMELX AMELX IL4 IL4 LUM LUM CCDC80 CCDC80 SSC5D SSC5D AGT AGT COL2A1 COL2A1 SLC17A5 SLC17A5 EMILIN2 EMILIN2 COL4A1 COL4A1 VCAN VCAN ADAMTS6 ADAMTS6 PLSCR2 PLSCR2 VWF VWF SOD3 SOD3 HMCN1 HMCN1 THBS1 THBS1 LOXL2 LOXL2 PODNL1 PODNL1 TNF TNF ACHE ACHE THBS4 THBS4 MATN2 MATN2 ENSPPAP00000023887 ENSPPAP00000023887 TGFBI TGFBI FBLN5 FBLN5 IMPG2 IMPG2 VTN VTN NCAM1 NCAM1 ENSPPAP00000028582 ENSPPAP00000028582 PLSCR1 PLSCR1 C11orf53 C11orf53 LTBP1 LTBP1 COL4A4 COL4A4 COL6A3 COL6A3 PCSK6 PCSK6 MMP9 MMP9 LAMB4 LAMB4 EGFL7 EGFL7 CETN2 CETN2 ACAN ACAN SMOC1 SMOC1 HSP90B1 HSP90B1 DCN DCN BCAN BCAN LAMA4 LAMA4 TNN TNN COL8A1 COL8A1 USHBP1 USHBP1 P3H2 P3H2 CASK CASK CHADL CHADL MMP2 MMP2 IL1B IL1B SPARC SPARC TGM4 TGM4 ADAMTS10 ADAMTS10 COMP COMP CXCL12 CXCL12 FBN2 FBN2 ENSPPAP00000036454 ENSPPAP00000036454 PKM PKM HSPG2 HSPG2 SERPINE2 SERPINE2 FN1 FN1 PVALB PVALB COL14A1 COL14A1 ENSPPAP00000037905 ENSPPAP00000037905 IFNG IFNG FRAS1 FRAS1 COCH COCH FBN1 FBN1 COL1A2 COL1A2 MMRN1 MMRN1 PAPLN PAPLN PTPRZ1 PTPRZ1 CILP CILP MS4A12 MS4A12 CD8A CD8A COL5A1 COL5A1 RARRES2 RARRES2 FBLN2 FBLN2 RBP3 RBP3 LAMA3 LAMA3 ENSPPAP00000003370 ENSPPAP00000003370 S100A4 S100A4 HAPLN4 HAPLN4 COL11A2 COL11A2 RELL2 RELL2 COL28A1 COL28A1 PERCC1 PERCC1 IL7 IL7 SSC4D SSC4D NCAN NCAN MATN1 MATN1 COL4A6 COL4A6 COL1A1 COL1A1 MEGF9 MEGF9 ENSPPAP00000000111 ENSPPAP00000000111 ADAMTS4 ADAMTS4 CD4 CD4 TNR TNR C6orf15 C6orf15 LAMB2 LAMB2 FREM1 FREM1 EGFLAM EGFLAM SFRP1 SFRP1 LAMC3 LAMC3 ICAM1 ICAM1 NID1 NID1 LAMC1 LAMC1 NID2 NID2 NAV2 NAV2 ECM2 ECM2 TNC TNC PXDN PXDN TGFBR2 TGFBR2 NTNG1 NTNG1 SHH SHH BGN BGN ZPLD1 ZPLD1 ABI3BP ABI3BP ANG ANG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL15A1Collagen type XV alpha 1 chain. (1388 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
COL8A2Collagen type VIII alpha 2 chain. (702 aa)
COL3A1Collagen type III alpha 1 chain. (1465 aa)
MFAP4Microfibril associated protein 4. (280 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (455 aa)
ECM1Extracellular matrix protein 1. (540 aa)
COL4A2Collagen type IV alpha 2 chain. (1711 aa)
TINAGTubulointerstitial nephritis antigen; Belongs to the peptidase C1 family. (476 aa)
AGRNAgrin. (1816 aa)
OTOL1Otolin 1. (474 aa)
LOC100970223Uncharacterized protein. (304 aa)
ZG16Zymogen granule protein 16. (167 aa)
MMRN2Multimerin 2. (896 aa)
APLP1Amyloid beta precursor like protein 1. (652 aa)
MATN3Matrilin 3. (486 aa)
LAMA1Laminin subunit alpha 1. (3104 aa)
COL4A3Collagen type IV alpha 3 chain. (1641 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
COL7A1Collagen type VII alpha 1 chain. (2944 aa)
USH2AUsherin. (5227 aa)
COL5A3Collagen type V alpha 3 chain. (1663 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (324 aa)
ANXA2Annexin. (339 aa)
LAMA5Laminin subunit alpha 5. (3648 aa)
IL13Interleukin 13. (146 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (176 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CD151Tetraspanin. (253 aa)
ANXA5Annexin. (320 aa)
C1QTNF9BC1q and TNF related 9B. (333 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
COL12A1Collagen type XII alpha 1 chain. (2982 aa)
VITVitrin. (693 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (163 aa)
NTN1Netrin 1. (528 aa)
COL26A1Collagen type XXVI alpha 1 chain. (388 aa)
LEFTY2Left-right determination factor. (366 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (303 aa)
COL6A2Collagen type VI alpha 2 chain. (998 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (800 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
POSTNPeriostin. (865 aa)
COL10A1Collagen type X alpha 1 chain. (680 aa)
MMP8Matrix metallopeptidase 8. (467 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1622 aa)
NTN4Netrin 4. (628 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
LOXLysyl oxidase. (417 aa)
COL4A5Collagen type IV alpha 5 chain. (1664 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
MATN4Matrilin 4. (622 aa)
ENSPPAP00000025633Uncharacterized protein. (58 aa)
FGFBP3Uncharacterized protein. (194 aa)
CCN1Cellular communication network factor 1. (381 aa)
TRIM33Tripartite motif containing 33. (1083 aa)
NTNG2Netrin G2. (530 aa)
ERBINErbb2 interacting protein. (1419 aa)
ANGPT1Angiopoietin 1. (498 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1270 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
PAQR4Progestin and adipoQ receptor family member 4. (273 aa)
MORC3MORC family CW-type zinc finger 3. (898 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
IL17AInterleukin 17A. (155 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
LAMB3Laminin subunit beta 3. (1171 aa)
ENSPPAP00000010225Pyruvate kinase; Belongs to the pyruvate kinase family. (504 aa)
FOXP3Forkhead box P3. (441 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
AMELXAmelogenin X-linked. (205 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
LUMLumican. (338 aa)
CCDC80Coiled-coil domain containing 80. (949 aa)
SSC5DScavenger receptor cysteine rich family member with 5 domains. (1419 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
COL2A1Uncharacterized protein. (1313 aa)
SLC17A5Solute carrier family 17 member 5. (495 aa)
EMILIN2Elastin microfibril interfacer 2. (1021 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
VCANVersican. (3396 aa)
ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif 6. (1117 aa)
PLSCR2Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (297 aa)
VWFVon Willebrand factor. (2813 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
HMCN1Hemicentin 1. (5622 aa)
THBS1Thrombospondin 1. (1173 aa)
LOXL2Lysyl oxidase like 2. (780 aa)
PODNL1Podocan like 1. (512 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (617 aa)
THBS4Thrombospondin 4. (870 aa)
MATN2Matrilin 2. (956 aa)
ENSPPAP00000023887LAM_G_DOMAIN domain-containing protein. (932 aa)
TGFBITransforming growth factor beta induced. (706 aa)
FBLN5Fibulin 5. (500 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1243 aa)
VTNVitronectin. (478 aa)
NCAM1Neural cell adhesion molecule 1. (873 aa)
ENSPPAP00000028582Annexin. (233 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (314 aa)
C11orf53Chromosome 11 open reading frame 53. (286 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1690 aa)
COL4A4Collagen type IV alpha 4 chain. (1690 aa)
COL6A3Uncharacterized protein. (2527 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (941 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
LAMB4Laminin subunit beta 4. (1746 aa)
EGFL7EGF like domain multiple 7. (273 aa)
CETN2Centrin 2. (172 aa)
ACANAggrecan. (2106 aa)
SMOC1SPARC related modular calcium binding 1. (430 aa)
HSP90B1Heat shock protein 90 beta family member 1. (814 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
BCANBrevican. (907 aa)
LAMA4Laminin subunit alpha 4. (1823 aa)
TNNTenascin N. (1299 aa)
COL8A1Collagen type VIII alpha 1 chain. (745 aa)
USHBP1USH1 protein network component harmonin binding protein 1. (703 aa)
P3H2Prolyl 3-hydroxylase 2. (636 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
CHADLUncharacterized protein. (555 aa)
MMP2Matrix metallopeptidase 2. (664 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
TGM4Prostate-specific transglutaminase 4. (684 aa)
ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10. (1103 aa)
COMPCartilage oligomeric matrix protein. (762 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
FBN2Fibrillin 2. (2866 aa)
ENSPPAP00000036454Uncharacterized protein. (305 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
HSPG2Heparan sulfate proteoglycan 2. (4369 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
FN1Fibronectin 1. (2477 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (110 aa)
COL14A1Collagen type XIV alpha 1 chain. (1795 aa)
ENSPPAP00000037905Uncharacterized protein. (608 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4012 aa)
COCHCochlin. (550 aa)
FBN1Fibrillin 1. (2871 aa)
COL1A2Collagen type I alpha 2 chain. (1274 aa)
MMRN1Multimerin 1. (1226 aa)
PAPLNPapilin, proteoglycan like sulfated glycoprotein. (1244 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2316 aa)
CILPCartilage intermediate layer protein. (1184 aa)
MS4A12Membrane spanning 4-domains A12. (267 aa)
CD8ACD8a molecule. (226 aa)
COL5A1Collagen type V alpha 1 chain. (1821 aa)
RARRES2Retinoic acid receptor responder 2. (163 aa)
FBLN2Fibulin 2. (1231 aa)
RBP3Retinol binding protein 3. (1247 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
ENSPPAP00000003370Uncharacterized protein. (1515 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
HAPLN4Hyaluronan and proteoglycan link protein 4. (409 aa)
COL11A2Collagen type XI alpha 2 chain. (1736 aa)
RELL2RELT like 2. (310 aa)
COL28A1Collagen type XXVIII alpha 1 chain. (1125 aa)
PERCC1Uncharacterized protein. (262 aa)
IL7Interleukin 7. (179 aa)
SSC4DUncharacterized protein. (464 aa)
NCANNeurocan. (1321 aa)
MATN1Matrilin 1. (496 aa)
COL4A6Collagen type IV alpha 6 chain. (1705 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
MEGF9Multiple EGF like domains 9. (600 aa)
ENSPPAP00000000111C1q domain-containing protein. (274 aa)
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4. (843 aa)
CD4CD4 molecule. (458 aa)
TNRTenascin R. (1360 aa)
C6orf15Chromosome 6 open reading frame 15. (325 aa)
LAMB2Laminin subunit beta 2. (1780 aa)
FREM1FRAS1 related extracellular matrix 1. (2179 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (984 aa)
SFRP1NTR domain-containing protein. (178 aa)
LAMC3Laminin subunit gamma 3. (1559 aa)
ICAM1Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (537 aa)
NID1Nidogen 1. (1247 aa)
LAMC1Laminin subunit gamma 1. (1609 aa)
NID2Nidogen 2. (1386 aa)
NAV2Neuron navigator 2. (2488 aa)
ECM2Extracellular matrix protein 2. (701 aa)
TNCTenascin C. (2201 aa)
PXDNPeroxidasin. (1479 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (570 aa)
NTNG1Netrin G1. (539 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (376 aa)
ZPLD1Zona pellucida like domain containing 1. (415 aa)
ABI3BPUncharacterized protein. (1571 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (147 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (40%) [HD]