45 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPPAP00000040216	MFS domain-containing protein. (228 aa)
	SERPINB6	Serpin family B member 6; Belongs to the serpin family. (412 aa)
	NBEAL2	Neurobeachin like 2. (2734 aa)
	ADAM8	ADAM metallopeptidase domain 8. (816 aa)
	SERPINB10	Serpin family B member 10; Belongs to the serpin family. (397 aa)
	TBC1D10C	TBC1 domain family member 10C. (446 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	ITGAX	Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa)
	CD300A	CD300a molecule. (299 aa)
	ENSPPAP00000035079	Uncharacterized protein. (513 aa)
	CD93	CD93 molecule. (650 aa)
	TMEM179B	Transmembrane protein 179B. (187 aa)
	CLEC4D	C-type lectin domain family 4 member D. (215 aa)
	CD58	CD58 molecule. (250 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1552 aa)
	DYNC1LI1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
	CLEC4C	C-type lectin domain family 4 member C. (201 aa)
	DYNLL1	Dynein light chain. (89 aa)
	PRCP	Prolylcarboxypeptidase. (496 aa)
	ATP6V0A1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
	ITGB2	Integrin beta. (806 aa)
	LOC100989777	Uncharacterized protein. (191 aa)
	STBD1	Starch binding domain 1. (358 aa)
	ADGRE3	Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (590 aa)
	RAC1	Uncharacterized protein. (224 aa)
	ENPP4	Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa)
	LOC100967790	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (663 aa)
	ARL8A	ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	SIRPA	Signal regulatory protein alpha. (504 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
	DOK3	Docking protein 3. (440 aa)
	DIAPH1	FH2 domain-containing protein. (507 aa)
	SIRPB1	Uncharacterized protein. (427 aa)
	NFASC	Neurofascin. (1338 aa)
	VPS35L	VPS35 endosomal protein sorting factor like. (1052 aa)
	SERPINB12	Serpin family B member 12; Belongs to the serpin family. (425 aa)
	FCAR	Fc fragment of IgA receptor. (286 aa)
	MGAM	Uncharacterized protein. (2753 aa)
	UBR4	Ubiquitin protein ligase E3 component n-recognin 4. (5183 aa)
	FPR1	Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	SLC2A3	Solute carrier family 2 member 3; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (433 aa)
	PKP1	Plakophilin 1. (747 aa)
	LOC100978613	Dynein light chain. (89 aa)
	SIGLEC14	Sialic acid binding Ig like lectin 14. (401 aa)
	PTPRN2	Protein tyrosine phosphatase receptor type N2. (977 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0A1	ATP6V0C	ENSPPAP00000023033	ENSPPAP00000037279	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
ATP6V0A1	TCIRG1	ENSPPAP00000023033	ENSPPAP00000013920	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.987
ATP6V0C	ATP6V0A1	ENSPPAP00000037279	ENSPPAP00000023033	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.997
ATP6V0C	DYNLL1	ENSPPAP00000037279	ENSPPAP00000025298	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Dynein light chain.	0.419
ATP6V0C	LOC100978613	ENSPPAP00000037279	ENSPPAP00000002720	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Dynein light chain.	0.419
ATP6V0C	TCIRG1	ENSPPAP00000037279	ENSPPAP00000013920	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.994
CD300A	ITGB2	ENSPPAP00000035496	ENSPPAP00000021180	CD300a molecule.	Integrin beta.	0.452
CD58	ITGAX	ENSPPAP00000027391	ENSPPAP00000036667	CD58 molecule.	Integrin subunit alpha X; Belongs to the integrin alpha chain family.	0.502
CD58	ITGB2	ENSPPAP00000027391	ENSPPAP00000021180	CD58 molecule.	Integrin beta.	0.584
CD93	ITGAX	ENSPPAP00000034493	ENSPPAP00000036667	CD93 molecule.	Integrin subunit alpha X; Belongs to the integrin alpha chain family.	0.585
CD93	ITGB2	ENSPPAP00000034493	ENSPPAP00000021180	CD93 molecule.	Integrin beta.	0.523
CLEC4C	ITGAX	ENSPPAP00000026650	ENSPPAP00000036667	C-type lectin domain family 4 member C.	Integrin subunit alpha X; Belongs to the integrin alpha chain family.	0.682
DIAPH1	LOC100989777	ENSPPAP00000012761	ENSPPAP00000020456	FH2 domain-containing protein.	Uncharacterized protein.	0.501
DIAPH1	RAC1	ENSPPAP00000012761	ENSPPAP00000019405	FH2 domain-containing protein.	Uncharacterized protein.	0.501
DYNC1LI1	DYNLL1	ENSPPAP00000026721	ENSPPAP00000025298	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Dynein light chain.	0.972
DYNC1LI1	LOC100978613	ENSPPAP00000026721	ENSPPAP00000002720	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Dynein light chain.	0.972
DYNLL1	ATP6V0C	ENSPPAP00000025298	ENSPPAP00000037279	Dynein light chain.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.419
DYNLL1	DYNC1LI1	ENSPPAP00000025298	ENSPPAP00000026721	Dynein light chain.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.972
DYNLL1	LOC100978613	ENSPPAP00000025298	ENSPPAP00000002720	Dynein light chain.	Dynein light chain.	0.900
ENSPPAP00000035079	SIGLEC14	ENSPPAP00000035079	ENSPPAP00000002548	Uncharacterized protein.	Sialic acid binding Ig like lectin 14.	0.770