(43 nodes) Tyrosine-specific protein phosphatase, PTPase domain network (Pan paniscus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTPRS	Protein tyrosine phosphatase receptor type S. (1873 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (878 aa)
	PTPRZ1	Protein tyrosine phosphatase receptor type Z1. (2316 aa)
	PTPN23	Protein tyrosine phosphatase non-receptor type 23. (1636 aa)
	PTPRB	Protein tyrosine phosphatase receptor type B. (2215 aa)
	PTPRN	Protein tyrosine phosphatase receptor type N. (973 aa)
	PTPN9	Protein tyrosine phosphatase non-receptor type 9. (583 aa)
	PTPRR	Protein tyrosine phosphatase receptor type R. (626 aa)
	PTPRF	Protein tyrosine phosphatase receptor type F. (1912 aa)
	PTP4A3	Protein tyrosine phosphatase 4A3. (173 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa)
	PTP4A2	Protein tyrosine phosphatase 4A2. (167 aa)
	PTPRD	Protein tyrosine phosphatase receptor type D. (1903 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1174 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1261 aa)
	ENSPPAP00000024034	Uncharacterized protein. (541 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	PTPRT	Protein tyrosine phosphatase receptor type T. (1421 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1216 aa)
	PTPN22	Protein tyrosine phosphatase non-receptor type 22. (807 aa)
	PTPN7	Protein tyrosine phosphatase non-receptor type 7. (464 aa)
	PTPRG	Protein tyrosine phosphatase receptor type G. (1445 aa)
	PTPN13	Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2485 aa)
	PTPRQ	Protein tyrosine phosphatase receptor type Q. (2259 aa)
	PTPRU	Protein tyrosine phosphatase receptor type U. (1296 aa)
	PTPRN2	Protein tyrosine phosphatase receptor type N2. (977 aa)
	PTPN4	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (912 aa)
	PTPRE	Receptor-type tyrosine-protein phosphatase. (700 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1465 aa)
	PTPRK	Protein tyrosine phosphatase receptor type K. (1472 aa)
	ENSPPAP00000006969	Uncharacterized protein. (584 aa)
	PTPRH	Protein tyrosine phosphatase receptor type H. (1096 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha. (802 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa)
	ENSPPAP00000009275	Uncharacterized protein. (269 aa)
	PTPN18	Protein tyrosine phosphatase non-receptor type 18. (435 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1313 aa)
	PTPN5	Protein tyrosine phosphatase non-receptor type 5. (565 aa)
	ENSPPAP00000029143	Uncharacterized protein. (511 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (424 aa)
	PTPN20	Protein tyrosine phosphatase non-receptor type 20. (419 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (780 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPAP00000006969	PTPN6	ENSPPAP00000006969	ENSPPAP00000009042	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.475
ENSPPAP00000009275	PTPN6	ENSPPAP00000009275	ENSPPAP00000009042	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.459
ENSPPAP00000024034	PTPN6	ENSPPAP00000024034	ENSPPAP00000009042	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.484
ENSPPAP00000029143	PTPN12	ENSPPAP00000029143	ENSPPAP00000013739	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.448
ENSPPAP00000029143	PTPN6	ENSPPAP00000029143	ENSPPAP00000009042	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.532
ENSPPAP00000029143	PTPN7	ENSPPAP00000029143	ENSPPAP00000026154	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 7.	0.417
PTPN1	PTPN11	ENSPPAP00000008568	ENSPPAP00000025051	Tyrosine-protein phosphatase non-receptor type.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.919
PTPN1	PTPRF	ENSPPAP00000008568	ENSPPAP00000034868	Tyrosine-protein phosphatase non-receptor type.	Protein tyrosine phosphatase receptor type F.	0.931
PTPN11	PTPN1	ENSPPAP00000025051	ENSPPAP00000008568	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type.	0.919
PTPN11	PTPN12	ENSPPAP00000025051	ENSPPAP00000013739	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.448
PTPN11	PTPN6	ENSPPAP00000025051	ENSPPAP00000009042	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.950
PTPN11	PTPN7	ENSPPAP00000025051	ENSPPAP00000026154	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Protein tyrosine phosphatase non-receptor type 7.	0.417
PTPN11	PTPRF	ENSPPAP00000025051	ENSPPAP00000034868	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Protein tyrosine phosphatase receptor type F.	0.913
PTPN12	ENSPPAP00000029143	ENSPPAP00000013739	ENSPPAP00000029143	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	Uncharacterized protein.	0.448
PTPN12	PTPN11	ENSPPAP00000013739	ENSPPAP00000025051	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.448
PTPN12	PTPN6	ENSPPAP00000013739	ENSPPAP00000009042	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.432
PTPN13	PTPRA	ENSPPAP00000028151	ENSPPAP00000007899	Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.	Receptor-type tyrosine-protein phosphatase alpha.	0.449
PTPN13	PTPRG	ENSPPAP00000028151	ENSPPAP00000027625	Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.	Protein tyrosine phosphatase receptor type G.	0.527
PTPN13	PTPRU	ENSPPAP00000028151	ENSPPAP00000000527	Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.	Protein tyrosine phosphatase receptor type U.	0.403
PTPN14	PTPN23	ENSPPAP00000015623	ENSPPAP00000039642	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Protein tyrosine phosphatase non-receptor type 23.	0.482