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LRG1 LRG1 LRIT2 LRIT2 LRRC4 LRRC4 RTN4RL1 RTN4RL1 LRRC24 LRRC24 LRRC55 LRRC55 TLR4 TLR4 TLR3 TLR3 LGI4 LGI4 IGSF10 IGSF10 LRTM2 LRTM2 SLIT3 SLIT3 NTRK1 NTRK1 PXDNL PXDNL LRFN2 LRFN2 LGI1 LGI1 ADGRA3 ADGRA3 LGI3 LGI3 LRIT1 LRIT1 SLITRK1 SLITRK1 NTRK2 NTRK2 CD180 CD180 TLR8 TLR8 CHADL CHADL LRIG3 LRIG3 LRFN3 LRFN3 LRIG1 LRIG1 ADGRA2 ADGRA2 LRTM1 LRTM1 MXRA5 MXRA5 CHAD CHAD NTRK3 NTRK3 LGI2 LGI2 PXDN PXDN SLIT2 SLIT2 ISLR ISLR TPBG TPBG FLRT3 FLRT3 AMIGO1 AMIGO1 VASN VASN GP9 GP9 FLRT2 FLRT2 RTN4R RTN4R TLR5 TLR5 LRRN3 LRRN3 SLITRK6 SLITRK6 LRRC19 LRRC19 SLITRK4 SLITRK4 TLR10 TLR10 ELFN1 ELFN1 LRRC4B LRRC4B LINGO4 LINGO4 AMIGO2 AMIGO2 TLR1 TLR1 LRRN1 LRRN1 CPN2 CPN2 FLRT1 FLRT1 SLITRK5 SLITRK5 SLIT1 SLIT1 TRIL TRIL SLITRK3 SLITRK3 IGFALS IGFALS TLR2 TLR2 SLITRK2 SLITRK2 LRRN2 LRRN2 LRRC38 LRRC38 LRFN1 LRFN1 TLR7 TLR7 LRFN4 LRFN4 ENSPPAP00000010920 ENSPPAP00000010920 LRRC17 LRRC17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
LRIT2Leucine rich repeat, Ig-like and transmembrane domains 2. (550 aa)
LRRC4Leucine rich repeat containing 4. (633 aa)
RTN4RL1Reticulon 4 receptor like 1. (441 aa)
LRRC24Ig-like domain-containing protein. (343 aa)
LRRC55Leucine rich repeat containing 55. (341 aa)
TLR4Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
LGI4Leucine rich repeat LGI family member 4. (537 aa)
IGSF10Immunoglobulin superfamily member 10. (2623 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (370 aa)
SLIT3Slit guidance ligand 3. (1527 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
PXDNLPeroxidasin like. (1441 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (789 aa)
LGI1Leucine rich glioma inactivated 1. (549 aa)
ADGRA3Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1285 aa)
LGI3Leucine rich repeat LGI family member 3. (548 aa)
LRIT1Leucine rich repeat, Ig-like and transmembrane domains 1. (623 aa)
SLITRK1SLIT and NTRK like family member 1. (580 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
CD180CD180 molecule. (661 aa)
TLR8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1041 aa)
CHADLUncharacterized protein. (555 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1026 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (617 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1088 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1306 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (343 aa)
MXRA5Matrix remodeling associated 5. (2853 aa)
CHADChondroadherin. (359 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
LGI2Leucine rich repeat LGI family member 2. (546 aa)
PXDNPeroxidasin. (1479 aa)
SLIT2Slit guidance ligand 2. (1410 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (428 aa)
TPBGTrophoblast glycoprotein. (419 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
VASNVasorin. (673 aa)
GP9Glycoprotein IX platelet. (177 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
RTN4RReticulon 4 receptor. (580 aa)
TLR5Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
LRRN3Leucine rich repeat neuronal 3. (708 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
LRRC19Leucine rich repeat containing 19. (370 aa)
SLITRK4SLIT and NTRK like family member 4. (837 aa)
TLR10TIR domain-containing protein; Belongs to the Toll-like receptor family. (811 aa)
ELFN1Extracellular leucine rich repeat and fibronectin type III domain containing 1. (828 aa)
LRRC4BLeucine rich repeat containing 4B. (715 aa)
LINGO4Leucine rich repeat and Ig domain containing 4. (593 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (522 aa)
TLR1Toll-like receptor. (786 aa)
LRRN1Leucine rich repeat neuronal 1. (716 aa)
CPN2Carboxypeptidase N subunit 2. (545 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (674 aa)
SLITRK5SLIT and NTRK like family member 5. (958 aa)
SLIT1Slit guidance ligand 1. (1533 aa)
TRILTLR4 interactor with leucine rich repeats. (811 aa)
SLITRK3SLIT and NTRK like family member 3. (977 aa)
IGFALSInsulin like growth factor binding protein acid labile subunit. (605 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
SLITRK2SLIT and NTRK like family member 2. (845 aa)
LRRN2Leucine rich repeat neuronal 2. (713 aa)
LRRC38Leucine rich repeat containing 38. (247 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (771 aa)
TLR7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (635 aa)
ENSPPAP00000010920LRRCT domain-containing protein. (488 aa)
LRRC17Leucine rich repeat containing 17. (440 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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