STRINGSTRING
LAMB3 LAMB3 OIT3 OIT3 CNTNAP2 CNTNAP2 DLL4 DLL4 LRP5 LRP5 ATRN ATRN ADAM2 ADAM2 OTOG OTOG ENSPPAP00000008808 ENSPPAP00000008808 MFGE8 MFGE8 PTGS1 PTGS1 PCSK5 PCSK5 PROS1 PROS1 LOC100990759 LOC100990759 LDLR LDLR MEGF8 MEGF8 MEGF6 MEGF6 DLK2 DLK2 VCAN VCAN TMEM8B TMEM8B PAMR1 PAMR1 LOC100987247 LOC100987247 SLIT1 SLIT1 BMP1 BMP1 HMCN1 HMCN1 HGFAC HGFAC THBS1 THBS1 THBD THBD TENM1 TENM1 ITGB4 ITGB4 NOTCH3 NOTCH3 MEP1B MEP1B F12 F12 FBLN2 FBLN2 LAMA3 LAMA3 PLAT PLAT ENSPPAP00000003405 ENSPPAP00000003405 CRELD2 CRELD2 UMODL1 UMODL1 ENSPPAP00000002689 ENSPPAP00000002689 TMEFF2 TMEFF2 CNTNAP4 CNTNAP4 NCAN NCAN VASN VASN MATN1 MATN1 EGF EGF MEGF9 MEGF9 LRP1B LRP1B SNED1 SNED1 LTBP1 LTBP1 DNER DNER LTBP2 LTBP2 NELL1 NELL1 CELSR1 CELSR1 UMOD UMOD SCARF2 SCARF2 MASP2 MASP2 MEGF10 MEGF10 STAB1 STAB1 TENM3 TENM3 ADAM15 ADAM15 ZAN ZAN PCSK6 PCSK6 NAGPA NAGPA PROC PROC EGFL7 EGFL7 TLL1 TLL1 ACAN ACAN PGAP6 PGAP6 F7 F7 BCAN BCAN LAMA4 LAMA4 NOTCH1 NOTCH1 HBEGF HBEGF TNN TNN ENSPPAP00000033699 ENSPPAP00000033699 F9 F9 THBS2 THBS2 ADAM33 ADAM33 CD93 CD93 NRXN1 NRXN1 MUC13 MUC13 DLL3 DLL3 TLL2 TLL2 COMP COMP SELE SELE FBN2 FBN2 LRP8 LRP8 HEG1 HEG1 HSPG2 HSPG2 TENM4 TENM4 CD248 CD248 DLK1 DLK1 LRP2 LRP2 FRAS1 FRAS1 FAT3 FAT3 LOC100992963 LOC100992963 FBN1 FBN1 AREG AREG MMRN1 MMRN1 EREG EREG TGFA TGFA STAB2 STAB2 PTGS2 PTGS2 ADAM8 ADAM8 LRP4 LRP4 SCUBE1 SCUBE1 MEGF11 MEGF11 NTNG1 NTNG1 SCUBE3 SCUBE3 SLIT2 SLIT2 ADGRE5 ADGRE5 LOC100988948 LOC100988948 ITGB8 ITGB8 ADGRE2 ADGRE2 THBS3 THBS3 ADGRL4 ADGRL4 DLL1 DLL1 VWDE VWDE CRB1 CRB1 IMPG2 IMPG2 TIE1 TIE1 MASP1 MASP1 LTBP3 LTBP3 ATRAID ATRAID ASTN1 ASTN1 NTNG2 NTNG2 PLAU PLAU TENM2 TENM2 ITGBL1 ITGBL1 MATN4 MATN4 PEAR1 PEAR1 FAT2 FAT2 LAMC2 LAMC2 MATN3 MATN3 ADAM28 ADAM28 FBLN5 FBLN5 NRG2 NRG2 F10 F10 TECTA TECTA MATN2 MATN2 C1R C1R THBS4 THBS4 EDIL3 EDIL3 RELN RELN VWCE VWCE TNR TNR LRP6 LRP6 LAMB2 LAMB2 SCUBE2 SCUBE2 JAG1 JAG1 PROZ PROZ EGFLAM EGFLAM NPNT NPNT TMEFF1 TMEFF1 TEK TEK TPO TPO LAMC3 LAMC3 NID1 NID1 MUC4 MUC4 ADAM32 ADAM32 LAMC1 LAMC1 ADAM11 ADAM11 NID2 NID2 VWA2 VWA2 SCARF1 SCARF1 NRG3 NRG3 SELP SELP ADGRE1 ADGRE1 ENSPPAP00000020734 ENSPPAP00000020734 TNC TNC SLIT3 SLIT3 FAT1 FAT1 ADGRE3 ADGRE3 ATRNL1 ATRNL1 NRG4 NRG4 BTC BTC HHIP HHIP FAT4 FAT4 EFEMP1 EFEMP1 SELL SELL CUBN CUBN NRXN3 NRXN3 ADAM19 ADAM19 FBLN1 FBLN1 LOC100967790 LOC100967790 NELL2 NELL2 HABP2 HABP2 AGRN AGRN FBN3 FBN3 ENSPPAP00000016342 ENSPPAP00000016342 CCBE1 CCBE1 FBLN7 FBLN7 CELSR3 CELSR3 LAMA1 LAMA1 LAMA5 LAMA5 CNTNAP5 CNTNAP5 GAS6 GAS6 JAG2 JAG2 TDGF1 TDGF1 ADAM9 ADAM9 CRB2 CRB2 SVEP1 SVEP1 WIF1 WIF1 NOTCH4 NOTCH4 CNTNAP1 CNTNAP1 HMCN2 HMCN2 ADAM23 ADAM23 NOTCH2 NOTCH2 ADAM22 ADAM22 LOC100987604 LOC100987604 NRXN2 NRXN2 ADAM30 ADAM30 EGFL6 EGFL6 LAMA2 LAMA2 NRG1 NRG1 ADAM21 ADAM21 LRP1 LRP1 VLDLR VLDLR LTBP4 LTBP4 MEP1A MEP1A LOC100968595 LOC100968595 LAMB1 LAMB1 SUSD1 SUSD1 ADAM12 ADAM12 EFEMP2 EFEMP2 CELSR2 CELSR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LAMB3Laminin subunit beta 3. (1171 aa)
OIT3Oncoprotein induced transcript 3. (557 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
LRP5LDL receptor related protein 5. (1839 aa)
ATRNAttractin. (1317 aa)
ADAM2ADAM metallopeptidase domain 2. (735 aa)
OTOGOtogelin. (2925 aa)
ENSPPAP00000008808Uncharacterized protein. (718 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (387 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1860 aa)
PROS1Protein S. (675 aa)
LOC100990759EGF-like domain-containing protein. (223 aa)
LDLRLow density lipoprotein receptor. (849 aa)
MEGF8Multiple EGF like domains 8. (2845 aa)
MEGF6Uncharacterized protein. (1390 aa)
DLK2Delta like non-canonical Notch ligand 2. (383 aa)
VCANVersican. (3396 aa)
TMEM8BTransmembrane protein 8B. (472 aa)
PAMR1Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (737 aa)
LOC100987247CFC domain-containing protein. (170 aa)
SLIT1Slit guidance ligand 1. (1533 aa)
BMP1Metalloendopeptidase. (986 aa)
HMCN1Hemicentin 1. (5622 aa)
HGFACHGF activator. (662 aa)
THBS1Thrombospondin 1. (1173 aa)
THBDThrombomodulin. (631 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
ITGB4Integrin beta. (1821 aa)
NOTCH3Notch receptor 3. (1981 aa)
MEP1BMeprin A subunit. (701 aa)
F12Coagulation factor XII. (615 aa)
FBLN2Fibulin 2. (1231 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
ENSPPAP00000003405Uncharacterized protein. (717 aa)
CRELD2Cysteine rich with EGF like domains 2. (364 aa)
UMODL1Uromodulin like 1. (1434 aa)
ENSPPAP00000002689CFC domain-containing protein. (158 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
CNTNAP4Uncharacterized protein. (1308 aa)
NCANNeurocan. (1321 aa)
VASNVasorin. (673 aa)
MATN1Matrilin 1. (496 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
MEGF9Multiple EGF like domains 9. (600 aa)
LRP1BLDL receptor related protein 1B. (4322 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1352 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1690 aa)
DNERDelta/notch like EGF repeat containing. (645 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1813 aa)
NELL1Neural EGFL like 1. (838 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2933 aa)
UMODUromodulin. (681 aa)
SCARF2Uncharacterized protein. (717 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
MEGF10Multiple EGF like domains 10. (1140 aa)
STAB1Stabilin 1. (2570 aa)
TENM3Teneurin transmembrane protein 3. (2703 aa)
ADAM15ADAM metallopeptidase domain 15. (863 aa)
ZANUncharacterized protein. (2336 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (941 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (498 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (461 aa)
EGFL7EGF like domain multiple 7. (273 aa)
TLL1Metalloendopeptidase. (1036 aa)
ACANAggrecan. (2106 aa)
PGAP6Transmembrane protein 8A. (771 aa)
F7Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity). Belongs to the peptidase S1 family. (444 aa)
BCANBrevican. (907 aa)
LAMA4Laminin subunit alpha 4. (1823 aa)
NOTCH1Notch receptor 1. (2573 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
TNNTenascin N. (1299 aa)
ENSPPAP00000033699Uncharacterized protein. (397 aa)
F9Coagulation factor IX. (486 aa)
THBS2Thrombospondin 2. (1172 aa)
ADAM33ADAM metallopeptidase domain 33. (817 aa)
CD93CD93 molecule. (650 aa)
NRXN1Neurexin 1. (1445 aa)
MUC13Mucin 13, cell surface associated. (496 aa)
DLL3Uncharacterized protein. (493 aa)
TLL2Metalloendopeptidase. (1015 aa)
COMPCartilage oligomeric matrix protein. (762 aa)
SELESelectin E. (612 aa)
FBN2Fibrillin 2. (2866 aa)
LRP8LDL receptor related protein 8. (927 aa)
HEG1Heart development protein with EGF like domains 1. (1275 aa)
HSPG2Heparan sulfate proteoglycan 2. (4369 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
CD248CD248 molecule. (726 aa)
DLK1Delta like non-canonical Notch ligand 1. (419 aa)
LRP2LDL receptor related protein 2. (4641 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4012 aa)
FAT3Uncharacterized protein. (892 aa)
LOC100992963Uncharacterized protein. (3854 aa)
FBN1Fibrillin 1. (2871 aa)
AREGEGF-like domain-containing protein. (274 aa)
MMRN1Multimerin 1. (1226 aa)
EREGEpiregulin. (169 aa)
TGFATransforming growth factor alpha. (181 aa)
STAB2Stabilin 2. (2551 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ADAM8ADAM metallopeptidase domain 8. (816 aa)
LRP4LDL receptor related protein 4. (1857 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (992 aa)
MEGF11Multiple EGF like domains 11. (990 aa)
NTNG1Netrin G1. (539 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
SLIT2Slit guidance ligand 2. (1410 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (743 aa)
LOC100988948Uncharacterized protein. (699 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (757 aa)
ADGRE2Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (764 aa)
THBS3Thrombospondin 3. (956 aa)
ADGRL4Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (691 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (624 aa)
VWDEUncharacterized protein. (1275 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1243 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (728 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1270 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
ASTN1Astrotactin 1. (1260 aa)
NTNG2Netrin G2. (530 aa)
PLAUPlasminogen activator, urokinase. (431 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
ITGBL1Integrin subunit beta like 1. (409 aa)
MATN4Matrilin 4. (622 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1029 aa)
FAT2FAT atypical cadherin 2. (4348 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
MATN3Matrilin 3. (486 aa)
ADAM28ADAM metallopeptidase domain 28. (797 aa)
FBLN5Fibulin 5. (500 aa)
NRG2Uncharacterized protein. (705 aa)
F10Coagulation factor X. (488 aa)
TECTATectorin alpha. (2155 aa)
MATN2Matrilin 2. (956 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (704 aa)
THBS4Thrombospondin 4. (870 aa)
EDIL3EGF like repeats and discoidin domains 3. (488 aa)
RELNReelin. (3460 aa)
VWCEVon Willebrand factor C and EGF domains. (955 aa)
TNRTenascin R. (1360 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
LAMB2Laminin subunit beta 2. (1780 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (980 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (422 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (984 aa)
NPNTNephronectin. (612 aa)
TMEFF1Uncharacterized protein. (454 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
TPOThyroid peroxidase. (933 aa)
LAMC3Laminin subunit gamma 3. (1559 aa)
NID1Nidogen 1. (1247 aa)
MUC4Uncharacterized protein. (1108 aa)
ADAM32ADAM metallopeptidase domain 32. (787 aa)
LAMC1Laminin subunit gamma 1. (1609 aa)
ADAM11ADAM metallopeptidase domain 11. (780 aa)
NID2Nidogen 2. (1386 aa)
VWA2Von Willebrand factor A domain containing 2. (712 aa)
SCARF1Scavenger receptor class F member 1. (830 aa)
NRG3Neuregulin 3. (719 aa)
SELPSelectin P. (830 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (886 aa)
ENSPPAP00000020734Uncharacterized protein. (622 aa)
TNCTenascin C. (2201 aa)
SLIT3Slit guidance ligand 3. (1527 aa)
FAT1FAT atypical cadherin 1. (4588 aa)
ADGRE3Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (590 aa)
ATRNL1Attractin like 1. (1379 aa)
NRG4Neuregulin 4. (117 aa)
BTCBetacellulin. (178 aa)
HHIPHedgehog interacting protein. (700 aa)
FAT4FAT atypical cadherin 4. (4983 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (493 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
CUBNCubilin. (3623 aa)
NRXN3Neurexin 3. (1664 aa)
ADAM19ADAM metallopeptidase domain 19. (918 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (720 aa)
LOC100967790Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (663 aa)
NELL2Neural EGFL like 2. (866 aa)
HABP2Hyaluronan binding protein 2. (560 aa)
AGRNAgrin. (1816 aa)
FBN3Fibrillin 3. (2809 aa)
ENSPPAP00000016342CFC domain-containing protein. (142 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
FBLN7Fibulin 7. (439 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3324 aa)
LAMA1Laminin subunit alpha 1. (3104 aa)
LAMA5Laminin subunit alpha 5. (3648 aa)
CNTNAP5Contactin associated protein like 5. (1307 aa)
GAS6Growth arrest specific 6. (679 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1099 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
CRB2Crumbs cell polarity complex component 2. (1083 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3571 aa)
WIF1WNT inhibitory factor 1. (379 aa)
NOTCH4Notch receptor 4. (2001 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
HMCN2Hemicentin 2. (5059 aa)
ADAM23ADAM metallopeptidase domain 23. (788 aa)
NOTCH2Notch receptor 2. (2254 aa)
ADAM22ADAM metallopeptidase domain 22. (889 aa)
LOC100987604Uncharacterized protein. (386 aa)
NRXN2Neurexin 2. (1671 aa)
ADAM30ADAM metallopeptidase domain 30. (794 aa)
EGFL6EGF like domain multiple 6. (553 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
NRG1Neuregulin 1. (645 aa)
ADAM21Uncharacterized protein. (706 aa)
LRP1LDL receptor related protein 1. (4544 aa)
VLDLRVery low density lipoprotein receptor. (1038 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1622 aa)
MEP1AMeprin A subunit. (762 aa)
LOC100968595Uncharacterized protein. (860 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
SUSD1Sushi domain containing 1. (688 aa)
ADAM12ADAM metallopeptidase domain 12. (874 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2908 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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