(26 nodes) ATPase, AAA-type, conserved site network (Pan paniscus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	FIGN	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
	AFG3L2	AFG3 like matrix AAA peptidase subunit 2. (797 aa)
	ENSPPAP00000007696	Uncharacterized protein; Belongs to the AAA ATPase family. (369 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (432 aa)
	BCS1L	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
	LOC100979126	Uncharacterized protein; Belongs to the AAA ATPase family. (462 aa)
	NVL	Nuclear VCP like. (848 aa)
	NSF	N-ethylmaleimide sensitive factor, vesicle fusing ATPase. (744 aa)
	PSMC4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
	ATAD2B	ATPase family AAA domain containing 2B. (1458 aa)
	KATNAL1	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (446 aa)
	PSMC6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (411 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (602 aa)
	PEX6	Peroxisomal biogenesis factor 6. (952 aa)
	YME1L1	YME1 like 1 ATPase. (773 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1283 aa)
	PSMC3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
	ATAD2	ATPase family AAA domain containing 2. (1387 aa)
	SPATA5	Spermatogenesis associated 5. (744 aa)
	ATAD1	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (363 aa)
	PSMC5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family. (669 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD2	PSMC3	ENSPPAP00000040568	ENSPPAP00000039415	ATPase family AAA domain containing 2.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.494
ATAD2	PSMC4	ENSPPAP00000040568	ENSPPAP00000017254	ATPase family AAA domain containing 2.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.494
ATAD2	PSMC6	ENSPPAP00000040568	ENSPPAP00000021237	ATPase family AAA domain containing 2.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.494
ATAD2B	PSMC3	ENSPPAP00000020191	ENSPPAP00000039415	ATPase family AAA domain containing 2B.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.494
ATAD2B	PSMC4	ENSPPAP00000020191	ENSPPAP00000017254	ATPase family AAA domain containing 2B.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.494
ATAD2B	PSMC6	ENSPPAP00000020191	ENSPPAP00000021237	ATPase family AAA domain containing 2B.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.494
ENSPPAP00000007696	PSMC2	ENSPPAP00000007696	ENSPPAP00000008794	Uncharacterized protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	0.960
ENSPPAP00000007696	PSMC3	ENSPPAP00000007696	ENSPPAP00000039415	Uncharacterized protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.959
ENSPPAP00000007696	PSMC4	ENSPPAP00000007696	ENSPPAP00000017254	Uncharacterized protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.976
ENSPPAP00000007696	PSMC5	ENSPPAP00000007696	ENSPPAP00000042030	Uncharacterized protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.980
ENSPPAP00000007696	PSMC6	ENSPPAP00000007696	ENSPPAP00000021237	Uncharacterized protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.974
ENSPPAP00000007696	SPATA5	ENSPPAP00000007696	ENSPPAP00000041585	Uncharacterized protein; Belongs to the AAA ATPase family.	Spermatogenesis associated 5.	0.481
ENSPPAP00000007696	SPATA5L1	ENSPPAP00000007696	ENSPPAP00000043222	Uncharacterized protein; Belongs to the AAA ATPase family.	Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family.	0.481
ENSPPAP00000007696	VCP	ENSPPAP00000007696	ENSPPAP00000035908	Uncharacterized protein; Belongs to the AAA ATPase family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.522
FIGN	LOC100979126	ENSPPAP00000020021	ENSPPAP00000013495	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.458
FIGN	VPS4B	ENSPPAP00000020021	ENSPPAP00000021043	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.	0.458
KATNA1	KATNAL1	ENSPPAP00000039981	ENSPPAP00000020640	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...]	0.423
KATNA1	PSMC3	ENSPPAP00000039981	ENSPPAP00000039415	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.530
KATNA1	PSMC4	ENSPPAP00000039981	ENSPPAP00000017254	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.523
KATNA1	PSMC6	ENSPPAP00000039981	ENSPPAP00000021237	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.523