STRINGSTRING
RET RET AATK AATK ZAP70 ZAP70 MATK MATK EPHA2 EPHA2 ROR1 ROR1 JAK1 JAK1 FLT3 FLT3 EPHA6 EPHA6 EPHB1 EPHB1 DDR1 DDR1 MUSK MUSK IGF1R IGF1R RYK RYK PTK6 PTK6 INSR INSR CSK CSK EGFR EGFR EPHA4 EPHA4 ABL2 ABL2 ALK ALK PTK2 PTK2 KDR KDR NTRK3 NTRK3 FLT4 FLT4 CSF1R CSF1R ERBB4 ERBB4 ERBB2 ERBB2 FGR FGR PLK4 PLK4 EPHA7 EPHA7 TEC TEC ENSPPAP00000014225 ENSPPAP00000014225 MERTK MERTK LYN LYN TNK1 TNK1 TESK2 TESK2 DDR2 DDR2 ENSPPAP00000015671 ENSPPAP00000015671 LCK LCK FGFR1 FGFR1 MST1R MST1R ITK ITK PDGFRA PDGFRA EPHA3 EPHA3 SRMS SRMS LMTK2 LMTK2 KIT KIT EPHB2 EPHB2 INSRR INSRR LTK LTK JAK3 JAK3 EPHA8 EPHA8 SRC SRC BMX BMX ROS1 ROS1 OBSCN OBSCN FER FER TYRO3 TYRO3 PTK7 PTK7 TESK1 TESK1 TYK2 TYK2 YES1 YES1 BTK BTK TP53RK TP53RK ENSPPAP00000030502 ENSPPAP00000030502 PTK2B PTK2B MET MET HCK HCK NTRK2 NTRK2 AXL AXL SYK SYK FRK FRK PDGFRB PDGFRB TXK TXK FGFR4 FGFR4 TIE1 TIE1 ENSPPAP00000026690 ENSPPAP00000026690 ABL1 ABL1 EPHA5 EPHA5 FYN FYN FES FES STYK1 STYK1 PRAG1 PRAG1 TTN TTN FGFR2 FGFR2 NEK10 NEK10 NTRK1 NTRK1 ROR2 ROR2 TEK TEK EPHB3 EPHB3 FGFR3 FGFR3 EPHB4 EPHB4 EPHA1 EPHA1 PEAK1 PEAK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1116 aa)
AATKApoptosis associated tyrosine kinase; Belongs to the globin family. (1374 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
MATKTyrosine-protein kinase. (514 aa)
EPHA2EPH receptor A2. (976 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
EPHA6EPH receptor A6. (980 aa)
EPHB1EPH receptor B1. (984 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (920 aa)
MUSKMuscle associated receptor tyrosine kinase. (879 aa)
IGF1RTyrosine-protein kinase receptor. (1389 aa)
RYKUncharacterized protein. (475 aa)
PTK6Tyrosine-protein kinase. (451 aa)
INSRTyrosine-protein kinase receptor. (1362 aa)
CSKTyrosine-protein kinase. (450 aa)
EGFRReceptor protein-tyrosine kinase. (1201 aa)
EPHA4EPH receptor A4. (986 aa)
ABL2Tyrosine-protein kinase. (1131 aa)
ALKTyrosine-protein kinase receptor. (1312 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1321 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
FGRTyrosine-protein kinase. (529 aa)
PLK4Polo like kinase 4. (970 aa)
EPHA7EPH receptor A7. (974 aa)
TECTyrosine-protein kinase. (631 aa)
ENSPPAP00000014225Protein kinase domain-containing protein. (433 aa)
MERTKMER proto-oncogene, tyrosine kinase. (966 aa)
LYNTyrosine-protein kinase. (526 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (666 aa)
TESK2Testis associated actin remodelling kinase 2. (545 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
ENSPPAP00000015671Protein kinase domain-containing protein. (414 aa)
LCKTyrosine-protein kinase. (524 aa)
FGFR1Fibroblast growth factor receptor. (812 aa)
MST1RMacrophage stimulating 1 receptor. (1400 aa)
ITKTyrosine-protein kinase. (620 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
EPHA3EPH receptor A3. (983 aa)
SRMSTyrosine-protein kinase. (491 aa)
LMTK2Lemur tyrosine kinase 2. (1503 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
EPHB2EPH receptor B2. (1039 aa)
INSRRTyrosine-protein kinase receptor. (1297 aa)
LTKTyrosine-protein kinase receptor. (864 aa)
JAK3Tyrosine-protein kinase. (1090 aa)
EPHA8EPH receptor A8. (997 aa)
SRCTyrosine-protein kinase. (458 aa)
BMXTyrosine-protein kinase. (679 aa)
ROS1Tyrosine-protein kinase receptor. (2347 aa)
OBSCNObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (8732 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (798 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
TESK1Testis associated actin remodelling kinase 1. (625 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
YES1Tyrosine-protein kinase. (548 aa)
BTKTyrosine-protein kinase. (693 aa)
TP53RKTP53 regulating kinase. (253 aa)
ENSPPAP00000030502Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (849 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1413 aa)
HCKTyrosine-protein kinase. (526 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
SYKTyrosine-protein kinase. (635 aa)
FRKTyrosine-protein kinase. (505 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
TXKTyrosine-protein kinase. (527 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
ENSPPAP00000026690Protein kinase domain-containing protein. (1250 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
EPHA5Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (370 aa)
FYNTyrosine-protein kinase. (537 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
STYK1Serine/threonine/tyrosine kinase 1. (422 aa)
PRAG1Protein kinase domain-containing protein. (956 aa)
TTNUncharacterized protein. (27117 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
NEK10Protein kinase domain-containing protein. (1173 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (982 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
EPHB3EPH receptor B3. (1031 aa)
FGFR3Fibroblast growth factor receptor. (780 aa)
EPHB4EPH receptor B4. (987 aa)
EPHA1EPH receptor A1. (965 aa)
PEAK1Protein kinase domain-containing protein. (707 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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