93 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HELT	Uncharacterized protein. (327 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (789 aa)
	TWIST1	BHLH domain-containing protein. (138 aa)
	MITF	Melanocyte inducing transcription factor. (519 aa)
	HES3	Hes family bHLH transcription factor 3. (185 aa)
	MAX	MYC associated factor X. (160 aa)
	ENSPPAP00000037955	BHLH domain-containing protein. (341 aa)
	NCOA1	Nuclear receptor coactivator. (1441 aa)
	HIF3A	Hypoxia inducible factor 3 subunit alpha. (669 aa)
	MXD4	BHLH domain-containing protein. (187 aa)
	BHMG1	Basic helix-loop-helix and HMG-box containing 1. (638 aa)
	TCF21	Transcription factor 21. (179 aa)
	ID1	Inhibitor of DNA binding 1, HLH protein. (155 aa)
	USF2	BHLH domain-containing protein. (224 aa)
	MYCN	BHLH domain-containing protein. (253 aa)
	MLX	MAX dimerization protein MLX. (298 aa)
	MLXIPL	MLX interacting protein like. (852 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
	TFEB	Transcription factor EB. (552 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (171 aa)
	ATOH8	Atonal bHLH transcription factor 8. (320 aa)
	USF3	Upstream transcription factor family member 3. (2220 aa)
	ARNTL2	Aryl hydrocarbon receptor nuclear translocator like 2. (624 aa)
	NPAS1	Neuronal PAS domain protein 1. (590 aa)
	TCF3	Transcription factor 3. (673 aa)
	NEUROG1	Neurogenin 1. (237 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	NHLH1	Nescient helix-loop-helix 1. (133 aa)
	ARNT2	Uncharacterized protein. (759 aa)
	TAL2	TAL bHLH transcription factor 2. (108 aa)
	TFEC	BHLH domain-containing protein. (437 aa)
	ENSPPAP00000001242	BHLH domain-containing protein. (117 aa)
	SIM1	Single-minded homolog 1; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult. (767 aa)
	FERD3L	Fer3 like bHLH transcription factor. (165 aa)
	ID3	Inhibitor of DNA binding 3, HLH protein. (119 aa)
	NEUROG3	Neurogenin 3. (214 aa)
	ARNTL	Aryl hydrocarbon receptor nuclear translocator like. (628 aa)
	SCX	BHLH domain-containing protein. (111 aa)
	OLIG3	Oligodendrocyte transcription factor 3. (272 aa)
	NEUROD4	BHLH domain-containing protein. (255 aa)
	NHLH2	Nescient helix-loop-helix 2. (135 aa)
	ATOH1	Atonal bHLH transcription factor 1. (356 aa)
	ASCL3	Achaete-scute family bHLH transcription factor 3. (181 aa)
	SOHLH2	BHLH domain-containing protein. (424 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa)
	MXI1	BHLH domain-containing protein. (203 aa)
	TCF15	BHLH domain-containing protein. (108 aa)
	LYL1	LYL1 basic helix-loop-helix family member. (233 aa)
	NPAS3	Neuronal PAS domain protein 3. (849 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	AHRR	Uncharacterized protein. (695 aa)
	TFE3	Transcription factor binding to IGHM enhancer 3. (575 aa)
	CLOCK	Clock circadian regulator. (847 aa)
	MYCL	MYCL proto-oncogene, bHLH transcription factor. (389 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (327 aa)
	MYOG	Myogenin. (249 aa)
	AHR	Uncharacterized protein. (850 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (268 aa)
	USF1	Upstream transcription factor 1. (310 aa)
	NCOA2	Nuclear receptor coactivator. (1464 aa)
	MLXIP	MLX interacting protein. (854 aa)
	NPAS2	Neuronal PAS domain protein 2. (827 aa)
	MYF6	Myogenic factor 6. (242 aa)
	SREBF2	Sterol regulatory element binding transcription factor 2. (1140 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (219 aa)
	SIM2	Uncharacterized protein. (630 aa)
	FIGLA	Folliculogenesis specific bHLH transcription factor. (219 aa)
	BHLHE40	Basic helix-loop-helix family member e40. (414 aa)
	NCOA3	Nuclear receptor coactivator. (1423 aa)
	TAL1	TAL bHLH transcription factor 1, erythroid differentiation factor. (291 aa)
	MSGN1	Mesogenin 1. (193 aa)
	TCFL5	BHLH domain-containing protein. (154 aa)
	TFAP4	Transcription factor AP-4. (337 aa)
	HES7	BHLH domain-containing protein. (129 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1177 aa)
	SOHLH1	Spermatogenesis and oogenesis specific basic helix-loop-helix 1. (387 aa)
	HES2	Hes family bHLH transcription factor 2. (173 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	MXD1	MAX dimerization protein 1. (221 aa)
	ID2	Inhibitor of DNA binding 2. (134 aa)
	TCF24	BHLH domain-containing protein. (120 aa)
	MGA	MAX dimerization protein MGA. (3068 aa)
	NPAS4	Neuronal PAS domain protein 4. (802 aa)
	TCF12	Transcription factor 12. (706 aa)
	TCF23	Transcription factor 23. (214 aa)
	BHLHE41	Uncharacterized protein. (272 aa)
	MXD3	BHLH domain-containing protein. (386 aa)
	MSC	BHLH domain-containing protein. (295 aa)
	TCF4	Transcription factor 4. (890 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (219 aa)
	EPAS1	Endothelial PAS domain protein 1. (870 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	ARNT	ENSPPAP00000014177	ENSPPAP00000035725	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.993
AHR	ARNT2	ENSPPAP00000014177	ENSPPAP00000000884	Uncharacterized protein.	Uncharacterized protein.	0.917
AHR	ARNTL	ENSPPAP00000014177	ENSPPAP00000003288	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator like.	0.665
AHR	ARNTL2	ENSPPAP00000014177	ENSPPAP00000034743	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator like 2.	0.665
AHR	CLOCK	ENSPPAP00000014177	ENSPPAP00000012930	Uncharacterized protein.	Clock circadian regulator.	0.665
AHR	NCOA1	ENSPPAP00000014177	ENSPPAP00000039056	Uncharacterized protein.	Nuclear receptor coactivator.	0.665
AHR	NCOA2	ENSPPAP00000014177	ENSPPAP00000016683	Uncharacterized protein.	Nuclear receptor coactivator.	0.665
AHR	NCOA3	ENSPPAP00000014177	ENSPPAP00000019674	Uncharacterized protein.	Nuclear receptor coactivator.	0.665
AHR	NPAS2	ENSPPAP00000014177	ENSPPAP00000018292	Uncharacterized protein.	Neuronal PAS domain protein 2.	0.665
AHRR	ARNT	ENSPPAP00000011108	ENSPPAP00000035725	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.805
AHRR	ARNT2	ENSPPAP00000011108	ENSPPAP00000000884	Uncharacterized protein.	Uncharacterized protein.	0.783
AHRR	ARNTL	ENSPPAP00000011108	ENSPPAP00000003288	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator like.	0.665
AHRR	ARNTL2	ENSPPAP00000011108	ENSPPAP00000034743	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator like 2.	0.665
AHRR	CLOCK	ENSPPAP00000011108	ENSPPAP00000012930	Uncharacterized protein.	Clock circadian regulator.	0.665
AHRR	NCOA1	ENSPPAP00000011108	ENSPPAP00000039056	Uncharacterized protein.	Nuclear receptor coactivator.	0.665
AHRR	NCOA2	ENSPPAP00000011108	ENSPPAP00000016683	Uncharacterized protein.	Nuclear receptor coactivator.	0.665
AHRR	NCOA3	ENSPPAP00000011108	ENSPPAP00000019674	Uncharacterized protein.	Nuclear receptor coactivator.	0.665
AHRR	NPAS2	ENSPPAP00000011108	ENSPPAP00000018292	Uncharacterized protein.	Neuronal PAS domain protein 2.	0.665
ARNT	AHR	ENSPPAP00000035725	ENSPPAP00000014177	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.993
ARNT	AHRR	ENSPPAP00000035725	ENSPPAP00000011108	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.805