STRINGSTRING
POLR2I POLR2I CCNK CCNK MNAT1 MNAT1 ENSPPAP00000022298 ENSPPAP00000022298 CDC73 CDC73 CCNH CCNH CDK9 CDK9 POLR2H POLR2H GTF2F2 GTF2F2 ERCC3 ERCC3 WDR61 WDR61 GTF2H2 GTF2H2 NCBP2 NCBP2 SUPT6H SUPT6H CCNT2 CCNT2 LOC100987164 LOC100987164 NELFA NELFA POLR2G POLR2G ENSPPAP00000034007 ENSPPAP00000034007 GTF2H4 GTF2H4 NELFE NELFE CTR9 CTR9 SSRP1 SSRP1 EAF1 EAF1 POLR2E POLR2E ELOC ELOC ELOA ELOA GTF2F1 GTF2F1 TCEA1 TCEA1 SUPT16H SUPT16H POLR2D POLR2D ERCC2 ERCC2 POLR2A POLR2A AFF4 AFF4 POLR2C POLR2C NELFCD NELFCD GTF2H5 GTF2H5 MLLT1 MLLT1 CTDP1 CTDP1 EAF2 EAF2 ENSPPAP00000037860 ENSPPAP00000037860 IWS1 IWS1 POLR2K POLR2K SUPT5H SUPT5H POLR2B POLR2B LEO1 LEO1 GTF2H3 GTF2H3 ELOB ELOB POLR2F POLR2F NCBP1 NCBP1 MLLT3 MLLT3 PAF1 PAF1 TCEB3CL2 TCEB3CL2 ELOA2 ELOA2 CDK7 CDK7 NELFB NELFB ELL ELL AFF1 AFF1 GTF2H1 GTF2H1 RTF1 RTF1 LOC100994688 LOC100994688 ENSPPAP00000018781 ENSPPAP00000018781 CCNT1 CCNT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
CCNKCyclin K; Belongs to the cyclin family. (576 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ENSPPAP00000022298Skp1_POZ domain-containing protein. (86 aa)
CDC73Cell division cycle 73. (531 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
WDR61WD repeat domain 61. (305 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
LOC100987164Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
NELFANegative elongation factor complex member A. (539 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
ENSPPAP00000034007Protein kinase domain-containing protein. (324 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
NELFENegative elongation factor complex member E. (389 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
SSRP1Structure specific recognition protein 1. (843 aa)
EAF1ELL associated factor 1. (268 aa)
POLR2ERNA polymerase II subunit E. (199 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ELOAElongin A. (798 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (516 aa)
TCEA1Transcription elongation factor A1. (304 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
POLR2DRPOL4c domain-containing protein. (110 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (2015 aa)
AFF4AF4/FMR2 family member 4. (1163 aa)
POLR2CRNA polymerase II subunit C. (273 aa)
NELFCDNegative elongation factor complex member C/D. (597 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
MLLT1MLLT1 super elongation complex subunit. (555 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (921 aa)
EAF2ELL associated factor 2. (260 aa)
ENSPPAP00000037860Uncharacterized protein. (852 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (819 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
SUPT5HTranscription elongation factor SPT5. (1089 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ELOBUncharacterized protein. (104 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
MLLT3MLLT3 super elongation complex subunit. (566 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (533 aa)
TCEB3CL2Uncharacterized protein. (298 aa)
ELOA2TFIIS N-terminal domain-containing protein. (558 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
NELFBNegative elongation factor complex member B. (684 aa)
ELLElongation factor for RNA polymerase II. (621 aa)
AFF1AF4/FMR2 family member 1. (1218 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (667 aa)
LOC100994688Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
ENSPPAP00000018781Uncharacterized protein. (136 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (707 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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