STRINGSTRING
GTF2F1 GTF2F1 POLR2C POLR2C NELFCD NELFCD GTF2H5 GTF2H5 CTDP1 CTDP1 POLR2K POLR2K SUPT5H SUPT5H POLR2B POLR2B GTF2H3 GTF2H3 NELFE NELFE GTF2H4 GTF2H4 ENSPPAP00000034007 ENSPPAP00000034007 POLR2G POLR2G NELFA NELFA NCBP2 NCBP2 CDK7 CDK7 NCBP1 NCBP1 POLR2F POLR2F POLR2A POLR2A POLR2E POLR2E GTF2H2 GTF2H2 ERCC3 ERCC3 GTF2F2 GTF2F2 POLR2H POLR2H CCNH CCNH C6orf15 C6orf15 MNAT1 MNAT1 POLR2I POLR2I ENSPPAP00000018781 ENSPPAP00000018781 GTF2H1 GTF2H1 NELFB NELFB ERCC2 ERCC2 POLR2D POLR2D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (516 aa)
POLR2CRNA polymerase II subunit C. (273 aa)
NELFCDNegative elongation factor complex member C/D. (597 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (921 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
SUPT5HTranscription elongation factor SPT5. (1089 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
NELFENegative elongation factor complex member E. (389 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
ENSPPAP00000034007Protein kinase domain-containing protein. (324 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
NELFANegative elongation factor complex member A. (539 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (2015 aa)
POLR2ERNA polymerase II subunit E. (199 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
C6orf15Chromosome 6 open reading frame 15. (325 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ENSPPAP00000018781Uncharacterized protein. (136 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
NELFBNegative elongation factor complex member B. (684 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
POLR2DRPOL4c domain-containing protein. (110 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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