STRINGSTRING
FABP1 FABP1 ARNT2 ARNT2 CD36 CD36 ENSPPAP00000001523 ENSPPAP00000001523 G0S2 G0S2 PLIN2 PLIN2 ARNTL ARNTL MED11 MED11 MED23 MED23 FAM120B FAM120B LOC100992554 LOC100992554 MED7 MED7 CPT1A CPT1A LOC100986655 LOC100986655 NR1H4 NR1H4 AGT AGT NR1H2 NR1H2 ENSPPAP00000009378 ENSPPAP00000009378 ENSPPAP00000009744 ENSPPAP00000009744 MED25 MED25 MED15 MED15 AHRR AHRR CCNC CCNC THRAP3 THRAP3 PPARG PPARG ENSPPAP00000011925 ENSPPAP00000011925 FDFT1 FDFT1 MED16 MED16 TRIB3 TRIB3 ENSPPAP00000012812 ENSPPAP00000012812 CLOCK CLOCK ENSPPAP00000013128 ENSPPAP00000013128 TNFRSF21 TNFRSF21 AHR AHR CARM1 CARM1 MED19 MED19 MED10 MED10 GRHL1 GRHL1 MED21 MED21 SIN3A SIN3A NCOA2 NCOA2 LOC100976271 LOC100976271 SP1 SP1 BCLAF1 BCLAF1 MED24 MED24 TXNRD1 TXNRD1 NFYC NFYC NPAS2 NPAS2 SREBF2 SREBF2 MED12 MED12 EP300 EP300 MAP7D3 MAP7D3 NCOA3 NCOA3 MTF1 MTF1 HMGCS2 HMGCS2 MED26 MED26 MED13 MED13 MED20 MED20 SREBF1 SREBF1 MED18 MED18 MED30 MED30 ENSPPAP00000022634 ENSPPAP00000022634 RGL1 RGL1 MED28 MED28 PPARGC1A PPARGC1A ANKRD2 ANKRD2 ANGPTL4 ANGPTL4 HMGCR HMGCR MED13L MED13L GPS2 GPS2 CDK8 CDK8 MED8 MED8 PPARGC1B PPARGC1B ANKRD1 ANKRD1 CYP1A1 CYP1A1 ACSL1 ACSL1 FHL5 FHL5 ACADM ACADM ACOX1 ACOX1 FHL2 FHL2 CPT2 CPT2 C7orf57 C7orf57 CDK19 CDK19 ESRRA ESRRA MED29 MED29 APOA2 APOA2 PEX11A PEX11A HDAC3 HDAC3 PPARA PPARA NRF1 NRF1 MED1 MED1 ABCA1 ABCA1 TBL1X TBL1X NCOR2 NCOR2 APOA5 APOA5 ARNT ARNT MAP7D2 MAP7D2 SULT2A1 SULT2A1 NFYB NFYB NFYA NFYA SLC27A1 SLC27A1 ME1 ME1 MED6 MED6 ALAS1 ALAS1 RXRA RXRA ENSPPAP00000038987 ENSPPAP00000038987 NCOA1 NCOA1 MED22 MED22 PASD1 PASD1 GRHL2 GRHL2 TBL1XR1 TBL1XR1 FADS1 FADS1 NR1D1 NR1D1 MED27 MED27 HMGCS1 HMGCS1 CYP7A1 CYP7A1 MED9 MED9 SIN3B SIN3B TIAM2 TIAM2 MED14 MED14 HELZ2 HELZ2 MED31 MED31 FHL3 FHL3 ABCB4 ABCB4 RORA RORA ENSPPAP00000030545 ENSPPAP00000030545 MED17 MED17 CREBBP CREBBP RXRB RXRB MED4 MED4 GLIPR1 GLIPR1 NR1H3 NR1H3 TGS1 TGS1 ENSPPAP00000032512 ENSPPAP00000032512 TXNRD3 TXNRD3 MAP7D1 MAP7D1 SMARCD3 SMARCD3 CHD9 CHD9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FABP1Fatty acid binding protein 1. (127 aa)
ARNT2Uncharacterized protein. (759 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ENSPPAP00000001523CBFD_NFYB_HMF domain-containing protein. (301 aa)
G0S2G0/G1 switch protein 2; Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers. (103 aa)
PLIN2Perilipin; Belongs to the perilipin family. (445 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
MED23Mediator complex subunit 23. (1370 aa)
FAM120BFamily with sequence similarity 120B. (909 aa)
LOC100992554Nuclear receptor corepressor 1. (2259 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (233 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
LOC100986655GPS2_interact domain-containing protein. (211 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (482 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
ENSPPAP00000009378Uncharacterized protein. (440 aa)
ENSPPAP00000009744Uncharacterized protein. (495 aa)
MED25Mediator complex subunit 25. (747 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (785 aa)
AHRRUncharacterized protein. (695 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
THRAP3Thyroid hormone receptor associated protein 3. (954 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ENSPPAP00000011925Uncharacterized protein. (383 aa)
FDFT1Farnesyl-diphosphate farnesyltransferase 1. (465 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (837 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
ENSPPAP00000012812Uncharacterized protein. (835 aa)
CLOCKClock circadian regulator. (847 aa)
ENSPPAP00000013128CBFD_NFYB_HMF domain-containing protein. (209 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
AHRUncharacterized protein. (850 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (629 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (260 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (135 aa)
GRHL1Grainyhead like transcription factor 1. (607 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (159 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
LOC100976271Uncharacterized protein. (249 aa)
SP1Sp1 transcription factor. (786 aa)
BCLAF1BCL2 associated transcription factor 1. (907 aa)
MED24Mediator complex subunit 24. (1008 aa)
TXNRD1Thioredoxin reductase 1. (648 aa)
NFYCNuclear transcription factor Y subunit gamma. (458 aa)
NPAS2Neuronal PAS domain protein 2. (827 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1140 aa)
MED12Mediator complex subunit 12. (2182 aa)
EP300E1A binding protein p300. (2411 aa)
MAP7D3MAP7 domain containing 3. (854 aa)
NCOA3Nuclear receptor coactivator. (1423 aa)
MTF1Metal regulatory transcription factor 1. (753 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
MED26TFIIS N-terminal domain-containing protein. (607 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (212 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
MED30Mediator complex subunit 30. (178 aa)
ENSPPAP00000022634Uncharacterized protein. (396 aa)
RGL1Ral guanine nucleotide dissociation stimulator like 1. (803 aa)
MED28Mediator complex subunit 28. (216 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
ANKRD2Ankyrin repeat domain 2. (360 aa)
ANGPTL4Angiopoietin like 4. (406 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (911 aa)
MED13LMediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2177 aa)
GPS2G protein pathway suppressor 2. (327 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (301 aa)
PPARGC1BPPARG coactivator 1 beta. (997 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
FHL5Four and a half LIM domains 5. (284 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (453 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
FHL2Four and a half LIM domains 2. (279 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
C7orf57Chromosome 7 open reading frame 57. (275 aa)
CDK19Cyclin dependent kinase 19. (502 aa)
ESRRAEstrogen related receptor alpha. (422 aa)
MED29Mediator complex subunit 29. (221 aa)
APOA2Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. (133 aa)
PEX11APeroxisomal biogenesis factor 11 alpha. (247 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
NRF1Nuclear respiratory factor 1. (503 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1555 aa)
ABCA1ATP binding cassette subfamily A member 1. (2264 aa)
TBL1XTransducin beta like 1 X-linked. (577 aa)
NCOR2Nuclear receptor corepressor 2. (2510 aa)
APOA5Apolipoprotein A5. (366 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
MAP7D2MAP7 domain containing 2. (772 aa)
SULT2A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa)
NFYBNuclear transcription factor Y subunit beta. (208 aa)
NFYANuclear transcription factor Y subunit alpha. (347 aa)
SLC27A1Solute carrier family 27 member 1. (646 aa)
ME1Malic enzyme. (572 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (249 aa)
ALAS15-aminolevulinate synthase. (640 aa)
RXRARetinoid X receptor alpha. (472 aa)
ENSPPAP00000038987Uncharacterized protein. (146 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
MED22Mediator complex subunit 22. (200 aa)
PASD1PAS domain containing repressor 1. (788 aa)
GRHL2Grainyhead like transcription factor 2. (618 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (545 aa)
FADS1Fatty acid desaturase 1. (501 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
MED27Mediator complex subunit 27. (311 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (601 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (147 aa)
SIN3BSIN3 transcription regulator family member B. (1159 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1730 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1466 aa)
HELZ2Helicase with zinc finger 2. (2649 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
FHL3Four and a half LIM domains 3. (280 aa)
ABCB4ATP binding cassette subfamily B member 4. (1279 aa)
RORARAR related orphan receptor A. (559 aa)
ENSPPAP00000030545Uncharacterized protein. (99 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (652 aa)
CREBBPCREB binding protein. (2414 aa)
RXRBRetinoid X receptor beta. (537 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
GLIPR1GLI pathogenesis related 1; Belongs to the CRISP family. (266 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
TGS1Trimethylguanosine synthase 1. (855 aa)
ENSPPAP00000032512Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (134 aa)
TXNRD3Thioredoxin reductase 3. (642 aa)
MAP7D1MAP7 domain containing 1. (821 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (430 aa)
CHD9Uncharacterized protein. (2383 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (22%) [HD]