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TUBB8 TUBB8 TUBA4B TUBA4B AP2B1 AP2B1 DNM3 DNM3 AP2A2 AP2A2 HMCN2 HMCN2 RPS6KA3 RPS6KA3 ENSPPAP00000012927 ENSPPAP00000012927 ENSPPAP00000012338 ENSPPAP00000012338 RPS6KA4 RPS6KA4 CLTC CLTC TUBA3C TUBA3C CLHC1 CLHC1 LOC100971548 LOC100971548 ACTRT1 ACTRT1 ENSPPAP00000006664 ENSPPAP00000006664 AP2A1 AP2A1 MAPK1 MAPK1 NUMB NUMB TUBB4A TUBB4A ENSPPAP00000005201 ENSPPAP00000005201 ACTL7B ACTL7B SH3GL2 SH3GL2 HMCN1 HMCN1 FNDC3B FNDC3B LOC100992883 LOC100992883 ACTL9 ACTL9 TUBA4A TUBA4A RPS6KA6 RPS6KA6 LOC100978544 LOC100978544 ACTL7A ACTL7A ACTRT2 ACTRT2 TUBB1 TUBB1 DNM2 DNM2 LOC100992709 LOC100992709 LOC100968784 LOC100968784 SHTN1 SHTN1 LOC100984538 LOC100984538 TUBA1B TUBA1B L1CAM L1CAM RPS6KA1 RPS6KA1 VSIG10L2 VSIG10L2 SRC SRC RDX RDX ENSPPAP00000035589 ENSPPAP00000035589 CLTA CLTA ENSPPAP00000031925 ENSPPAP00000031925 RPS6KA2 RPS6KA2 RPS6KA5 RPS6KA5 KIF4A KIF4A ACTB ACTB ACTG1 ACTG1 EZR EZR TUBAL3 TUBAL3 DPYSL2 DPYSL2 AP2M1 AP2M1 ENSPPAP00000024326 ENSPPAP00000024326 LOC100987691 LOC100987691 MSN MSN TUBB4B TUBB4B ENSPPAP00000022115 ENSPPAP00000022115 LOC100971602 LOC100971602 DNM1 DNM1 ACTL8 ACTL8 TUBA8 TUBA8 TUBA1C TUBA1C FNDC3A FNDC3A VSIG10L VSIG10L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TUBB8Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (414 aa)
TUBA4BTubulin alpha 4b. (241 aa)
AP2B1AP complex subunit beta. (951 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (943 aa)
HMCN2Hemicentin 2. (5059 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
ENSPPAP00000012927Uncharacterized protein; Belongs to the actin family. (336 aa)
ENSPPAP00000012338Tubulin domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (276 aa)
RPS6KA4Ribosomal protein S6 kinase. (772 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
TUBA3CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
LOC100971548Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (343 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (376 aa)
ENSPPAP00000006664Tubulin domain-containing protein. (84 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
NUMBNUMB endocytic adaptor protein. (651 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ENSPPAP00000005201Clat_adaptor_s domain-containing protein. (54 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (337 aa)
HMCN1Hemicentin 1. (5622 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
LOC100992883Uncharacterized protein; Belongs to the tubulin family. (615 aa)
ACTL9Actin like 9; Belongs to the actin family. (416 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
LOC100978544Uncharacterized protein. (893 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (785 aa)
LOC100992709FERM domain-containing protein. (517 aa)
LOC100968784Uncharacterized protein; Belongs to the actin family. (364 aa)
SHTN1Shootin 1. (636 aa)
LOC100984538Uncharacterized protein; Belongs to the tubulin family. (366 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
VSIG10L2V-set and immunoglobulin domain containing 10 like 2. (767 aa)
SRCTyrosine-protein kinase. (458 aa)
RDXRadixin. (609 aa)
ENSPPAP00000035589Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (88 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa)
ENSPPAP00000031925FERM domain-containing protein. (502 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1229 aa)
ACTBActin beta; Belongs to the actin family. (372 aa)
ACTG1Actin gamma 1. (375 aa)
EZREzrin. (604 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
DPYSL2Dihydropyrimidinase like 2. (681 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa)
ENSPPAP00000024326Uncharacterized protein. (370 aa)
LOC100987691Uncharacterized protein; Belongs to the actin family. (223 aa)
MSNMoesin. (591 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (433 aa)
ENSPPAP00000022115Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (435 aa)
LOC100971602Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (827 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (519 aa)
FNDC3AFibronectin type III domain containing 3A. (1216 aa)
VSIG10LV-set and immunoglobulin domain containing 10 like. (806 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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