STRINGSTRING
FZD5 FZD5 HMGXB3 HMGXB3 WNT8A WNT8A AMER1 AMER1 ENSPPAP00000002693 ENSPPAP00000002693 PPP2R5A PPP2R5A PPP2R1A PPP2R1A CSNK1A1L CSNK1A1L DVL1 DVL1 PPP2R5E PPP2R5E WNT1 WNT1 PPP2R1B PPP2R1B LOC100968831 LOC100968831 LRP5 LRP5 CSNK1G3 CSNK1G3 PPP2R5D PPP2R5D PPP2CA PPP2CA AXIN1 AXIN1 DVL2 DVL2 ENSPPAP00000017361 ENSPPAP00000017361 APC APC PPP2R5B PPP2R5B WNT3A WNT3A LRP6 LRP6 CTNNB1 CTNNB1 PPP2CB PPP2CB CAV1 CAV1 PPP2R5C PPP2R5C LOC103786139 LOC103786139 ENSPPAP00000033149 ENSPPAP00000033149 ENSPPAP00000033311 ENSPPAP00000033311 LRP5L LRP5L WNT8B WNT8B GSK3B GSK3B CSNK1A1 CSNK1A1 DVL3 DVL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
HMGXB3HMG-box containing 3. (1538 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
AMER1APC membrane recruitment protein 1. (1136 aa)
ENSPPAP00000002693Uncharacterized protein. (285 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa)
DVL1Dishevelled segment polarity protein 1. (674 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (469 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (660 aa)
LOC100968831Uncharacterized protein. (212 aa)
LRP5LDL receptor related protein 5. (1839 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (455 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (668 aa)
PPP2CASerine/threonine-protein phosphatase. (294 aa)
AXIN1Axin 1. (862 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
ENSPPAP00000017361Uncharacterized protein. (81 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
CTNNB1Catenin beta 1. (781 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
LOC103786139Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (479 aa)
ENSPPAP00000033149Serine/threonine-protein phosphatase. (223 aa)
ENSPPAP00000033311Protein kinase domain-containing protein. (305 aa)
LRP5LLDL receptor related protein 5 like. (252 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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