STRINGSTRING
PRKCZ PRKCZ FNDC3B FNDC3B SPHK1 SPHK1 CSDE1 CSDE1 ERAS ERAS VEGFA VEGFA AHCYL1 AHCYL1 ITPR2 ITPR2 HRAS HRAS ENSPPAP00000011278 ENSPPAP00000011278 RASA1 RASA1 PRKCA PRKCA PLCG1 PLCG1 FNDC3A FNDC3A PRKCD PRKCD PRKCB PRKCB CALM3 CALM3 NRAS NRAS KRAS KRAS ITPR3 ITPR3 SRC SRC ITPR1 ITPR1 KDR KDR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
SPHK1Sphingosine kinase 1. (470 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ERASES cell expressed Ras. (233 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (372 aa)
AHCYL1AdoHcyase_NAD domain-containing protein. (280 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSPPAP00000011278Protein kinase domain-containing protein. (351 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1248 aa)
FNDC3AFibronectin type III domain containing 3A. (1216 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa)
SRCTyrosine-protein kinase. (458 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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