STRINGSTRING
PARP3 PARP3 BIVM BIVM ENSPPAP00000035310 ENSPPAP00000035310 XPA XPA ERCC3 ERCC3 VWA5A VWA5A GTF2H2 GTF2H2 KCTD2 KCTD2 ENSPPAP00000028443 ENSPPAP00000028443 RPA3 RPA3 LOC100991563 LOC100991563 CETN2 CETN2 CHD1L CHD1L VWA5B1 VWA5B1 SUMO1 SUMO1 RPA1 RPA1 ENSPPAP00000034007 ENSPPAP00000034007 GTF2H4 GTF2H4 DDB2 DDB2 SUMO3 SUMO3 UBE2I UBE2I RAD23A RAD23A UBC UBC ENSPPAP00000005391 ENSPPAP00000005391 RNF111 RNF111 VTCN1 VTCN1 LOC100990877 LOC100990877 WDR76 WDR76 ENSPPAP00000008048 ENSPPAP00000008048 VWA5B2 VWA5B2 ENSPPAP00000008828 ENSPPAP00000008828 LOC100988108 LOC100988108 ENSPPAP00000009924 ENSPPAP00000009924 CDK7 CDK7 UBE2N UBE2N CUL4B CUL4B GTF2H1 GTF2H1 ENSPPAP00000013353 ENSPPAP00000013353 ENSPPAP00000014117 ENSPPAP00000014117 PIAS3 PIAS3 ENSPPAP00000017097 ENSPPAP00000017097 NFATC2IP NFATC2IP RBX1 RBX1 MEIOB MEIOB ENSPPAP00000018781 ENSPPAP00000018781 ENSPPAP00000019066 ENSPPAP00000019066 ENSPPAP00000019542 ENSPPAP00000019542 MNAT1 MNAT1 CUL4A CUL4A USP45 USP45 RPS27A RPS27A CCNH CCNH ERCC4 ERCC4 DDB1 DDB1 PARP2 PARP2 GTF2H3 GTF2H3 ERCC2 ERCC2 ERCC1 ERCC1 XPC XPC UBE2V2 UBE2V2 ENSPPAP00000040700 ENSPPAP00000040700 LOC100987671 LOC100987671 KXD1 KXD1 GTF2H5 GTF2H5 CETN3 CETN3 PIAS1 PIAS1 RAD23B RAD23B PARP1 PARP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PARP3Poly [ADP-ribose] polymerase. (539 aa)
BIVMBIVM-ERCC5 readthrough. (1640 aa)
ENSPPAP00000035310Uncharacterized protein. (121 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
VWA5AVon Willebrand factor A domain containing 5A. (786 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
KCTD2Uncharacterized protein. (64 aa)
ENSPPAP00000028443Rad60-SLD domain-containing protein. (118 aa)
RPA3Replication protein A3. (121 aa)
LOC100991563Rad60-SLD domain-containing protein. (72 aa)
CETN2Centrin 2. (172 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (921 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1215 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
ENSPPAP00000034007Protein kinase domain-containing protein. (324 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
SUMO3Small ubiquitin-related modifier. (103 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
UBCUncharacterized protein. (153 aa)
ENSPPAP00000005391Rad60-SLD domain-containing protein. (84 aa)
RNF111Ring finger protein 111. (993 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
LOC100990877Ubiquitin-like domain-containing protein. (156 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (625 aa)
ENSPPAP00000008048Rad60-SLD domain-containing protein. (62 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1242 aa)
ENSPPAP00000008828UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
LOC100988108Rad60-SLD domain-containing protein. (74 aa)
ENSPPAP00000009924Ubiquitin-like domain-containing protein. (84 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
CUL4BCullin 4B; Belongs to the cullin family. (932 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
ENSPPAP00000013353Uncharacterized protein. (117 aa)
ENSPPAP00000014117Ubiquitin-like domain-containing protein. (145 aa)
PIAS3Protein inhibitor of activated STAT 3. (628 aa)
ENSPPAP00000017097Rad60-SLD domain-containing protein. (140 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (419 aa)
RBX1Ring-box 1. (108 aa)
MEIOBUncharacterized protein. (344 aa)
ENSPPAP00000018781Uncharacterized protein. (136 aa)
ENSPPAP00000019066UBIQUITIN_CONJUGAT_2 domain-containing protein. (95 aa)
ENSPPAP00000019542Ubiquitin-like domain-containing protein. (136 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CUL4ACullin 4A; Belongs to the cullin family. (669 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (814 aa)
RPS27ARibosomal protein S27a. (156 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
PARP2Poly [ADP-ribose] polymerase. (565 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (297 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (946 aa)
UBE2V2UBIQUITIN_CONJUGAT_2 domain-containing protein. (151 aa)
ENSPPAP00000040700UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
LOC100987671UBIQUITIN_CONJUGAT_2 domain-containing protein. (88 aa)
KXD1Ubiquitin-like domain-containing protein. (231 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
CETN3Centrin 3. (191 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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