49 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TOB1	Transducer of ERBB2, 1. (345 aa)
	CDC25C	Cell division cycle 25C. (472 aa)
	LOC100968388	Uncharacterized protein. (273 aa)
	CNOT2	CCR4-NOT transcription complex subunit 2. (550 aa)
	BTG4	BTG anti-proliferation factor 4. (229 aa)
	ENSPPAP00000040884	Uncharacterized protein. (263 aa)
	PLAGL2	PLAG1 like zinc finger 2. (496 aa)
	CNOT8	CCR4-NOT transcription complex subunit 8. (292 aa)
	PLAG1	PLAG1 zinc finger. (500 aa)
	ENSPPAP00000042406	Uncharacterized protein. (234 aa)
	CNOT3	CCR4-NOT transcription complex subunit 3. (753 aa)
	TCP10L	T-complex 10 like. (209 aa)
	BTG2	BTG anti-proliferation factor 2. (158 aa)
	ENSPPAP00000003657	Uncharacterized protein. (450 aa)
	CNOT1	CCR4-NOT transcription complex subunit 1. (2383 aa)
	PLK5	Polo like kinase 5. (336 aa)
	CNOT10	CCR4-NOT transcription complex subunit 10. (804 aa)
	ENSPPAP00000009428	Uncharacterized protein. (295 aa)
	ENSPPAP00000009956	Uncharacterized protein. (245 aa)
	ENSPPAP00000010199	Uncharacterized protein. (312 aa)
	LOC100978286	Uncharacterized protein. (249 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
	ENSPPAP00000011287	Uncharacterized protein. (271 aa)
	CNOT6L	CCR4-NOT transcription complex subunit 6 like. (548 aa)
	CENPJ	Centromere protein J. (1338 aa)
	PRDM15	PR/SET domain 15. (1469 aa)
	TCP10	Tcp10_C domain-containing protein. (155 aa)
	CNOT6	CCR4-NOT transcription complex subunit 6. (557 aa)
	CNOT11	CCR4-NOT transcription complex subunit 11. (434 aa)
	ENSPPAP00000022078	Endo/exonuclease/phosphatase domain-containing protein. (470 aa)
	RGCC	Regulator of cell cycle. (137 aa)
	RAB11FIP4	RAB11 family interacting protein 4. (603 aa)
	ENSPPAP00000027138	Uncharacterized protein. (279 aa)
	PLK3	Serine/threonine-protein kinase PLK. (673 aa)
	CNOT7	CCR4-NOT transcription complex subunit 7. (285 aa)
	CNOT9	CCR4-NOT transcription complex subunit 9. (331 aa)
	HIGD1B	HIG1 hypoxia inducible domain family member 1B. (99 aa)
	LRRC27	Leucine rich repeat containing 27. (530 aa)
	ENSPPAP00000031085	Uncharacterized protein. (277 aa)
	TNKS1BP1	Tankyrase 1 binding protein 1. (1727 aa)
	PLAGL1	PLAG1 like zinc finger 1. (463 aa)
	LOC100971311	Uncharacterized protein. (261 aa)
	PLK2	Serine/threonine-protein kinase PLK. (685 aa)
	TCP10L2	Uncharacterized protein. (106 aa)
	ENSPPAP00000035595	Uncharacterized protein. (261 aa)
	ENSPPAP00000036339	Uncharacterized protein. (244 aa)
	BTG3	BTG anti-proliferation factor 3. (296 aa)
	NPM1	Nucleophosmin 1. (294 aa)
	CNOT4	CCR4-NOT transcription complex subunit 4. (712 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTG2	CNOT1	ENSPPAP00000001840	ENSPPAP00000005518	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 1.	0.656
BTG2	CNOT10	ENSPPAP00000001840	ENSPPAP00000007869	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 10.	0.585
BTG2	CNOT11	ENSPPAP00000001840	ENSPPAP00000019803	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 11.	0.605
BTG2	CNOT2	ENSPPAP00000001840	ENSPPAP00000039832	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 2.	0.577
BTG2	CNOT3	ENSPPAP00000001840	ENSPPAP00000000824	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 3.	0.565
BTG2	CNOT4	ENSPPAP00000001840	ENSPPAP00000038531	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 4.	0.527
BTG2	CNOT6	ENSPPAP00000001840	ENSPPAP00000018255	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 6.	0.504
BTG2	CNOT6L	ENSPPAP00000001840	ENSPPAP00000014122	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 6 like.	0.615
BTG2	CNOT7	ENSPPAP00000001840	ENSPPAP00000028144	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 7.	0.811
BTG2	CNOT8	ENSPPAP00000001840	ENSPPAP00000042181	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 8.	0.723
BTG2	CNOT9	ENSPPAP00000001840	ENSPPAP00000028310	BTG anti-proliferation factor 2.	CCR4-NOT transcription complex subunit 9.	0.511
BTG2	ENSPPAP00000009956	ENSPPAP00000001840	ENSPPAP00000009956	BTG anti-proliferation factor 2.	Uncharacterized protein.	0.811
BTG2	ENSPPAP00000022078	ENSPPAP00000001840	ENSPPAP00000022078	BTG anti-proliferation factor 2.	Endo/exonuclease/phosphatase domain-containing protein.	0.615
BTG2	ENSPPAP00000031085	ENSPPAP00000001840	ENSPPAP00000031085	BTG anti-proliferation factor 2.	Uncharacterized protein.	0.590
BTG2	ENSPPAP00000036339	ENSPPAP00000001840	ENSPPAP00000036339	BTG anti-proliferation factor 2.	Uncharacterized protein.	0.811
BTG2	LRRC27	ENSPPAP00000001840	ENSPPAP00000028488	BTG anti-proliferation factor 2.	Leucine rich repeat containing 27.	0.470
BTG2	TP53	ENSPPAP00000001840	ENSPPAP00000011040	BTG anti-proliferation factor 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.763
BTG3	CNOT1	ENSPPAP00000036720	ENSPPAP00000005518	BTG anti-proliferation factor 3.	CCR4-NOT transcription complex subunit 1.	0.556
BTG3	CNOT10	ENSPPAP00000036720	ENSPPAP00000007869	BTG anti-proliferation factor 3.	CCR4-NOT transcription complex subunit 10.	0.633
BTG3	CNOT11	ENSPPAP00000036720	ENSPPAP00000019803	BTG anti-proliferation factor 3.	CCR4-NOT transcription complex subunit 11.	0.828