56 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPC5	Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
	AKR1C3	Aldo-keto reductase family 1 member C3. (323 aa)
	RBP1	Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa)
	PLB1	Phospholipase B1. (1459 aa)
	LDLR	Low density lipoprotein receptor. (849 aa)
	APOA1	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family. (267 aa)
	CLPS	Colipase. (112 aa)
	SDC4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
	LOC100988315	Aldo_ket_red domain-containing protein. (303 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
	APOC3	Apolipoprotein C3. (99 aa)
	GPC3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
	BCO1	Beta-carotene oxygenase 1. (547 aa)
	APOB	Apolipoprotein B. (4535 aa)
	GPC2	Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (508 aa)
	LRP1B	LDL receptor related protein 1B. (4322 aa)
	TTR	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
	UBIAD1	UbiA prenyltransferase domain containing 1. (338 aa)
	APOC2	Uncharacterized protein. (178 aa)
	VKORC1L1	VKc domain-containing protein. (97 aa)
	LRP2	LDL receptor related protein 2. (4641 aa)
	LRAT	Lecithin retinol acyltransferase. (230 aa)
	RBP4	Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
	HSPG2	Heparan sulfate proteoglycan 2. (4369 aa)
	BCO2	Beta-carotene oxygenase 2. (579 aa)
	LRP8	LDL receptor related protein 8. (927 aa)
	LRP12	LDL receptor related protein 12. (845 aa)
	TTPA	Alpha tocopherol transfer protein. (278 aa)
	GPC6	Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (501 aa)
	SDC1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (334 aa)
	VKORC1	Vitamin K epoxide reductase complex subunit 1. (163 aa)
	APOA4	Apolipoprotein A4. (396 aa)
	RDH11	Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	APOA2	Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. (133 aa)
	LRP3	LDL receptor related protein 3. (774 aa)
	GPC1	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (636 aa)
	ENSPPAP00000027118	Uncharacterized protein. (125 aa)
	GPC4	Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
	LOC103783188	Aldo_ket_red domain-containing protein. (205 aa)
	PYROXD2	Pyridine nucleotide-disulphide oxidoreductase domain 2. (581 aa)
	APOE	Apolipoprotein E. (317 aa)
	SDC2	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
	ENSPPAP00000021541	Uncharacterized protein. (87 aa)
	GPIHBP1	Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (184 aa)
	APOM	Apolipoprotein M. (188 aa)
	AKR1C1	Aldo-keto reductase family 1 member C1. (295 aa)
	AKR1C4	Aldo-keto reductase family 1 member C4. (323 aa)
	AKR1B10	Aldo-keto reductase family 1 member B10. (307 aa)
	ENSPPAP00000018003	Uncharacterized protein. (3229 aa)
	SDC3	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (396 aa)
	RETSAT	Retinol saturase. (610 aa)
	RBP2	Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
	AGRN	Agrin. (1816 aa)
	TTPAL	Alpha tocopherol transfer protein like. (342 aa)
	LRP1	LDL receptor related protein 1. (4544 aa)
	LRP10	LDL receptor related protein 10. (715 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	APOB	ENSPPAP00000016637	ENSPPAP00000002804	Agrin.	Apolipoprotein B.	0.549
AGRN	APOC3	ENSPPAP00000016637	ENSPPAP00000003943	Agrin.	Apolipoprotein C3.	0.444
AGRN	APOE	ENSPPAP00000016637	ENSPPAP00000022762	Agrin.	Apolipoprotein E.	0.584
AGRN	ENSPPAP00000018003	ENSPPAP00000016637	ENSPPAP00000018003	Agrin.	Uncharacterized protein.	0.406
AGRN	GPC1	ENSPPAP00000016637	ENSPPAP00000027370	Agrin.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.614
AGRN	GPC3	ENSPPAP00000016637	ENSPPAP00000003571	Agrin.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.420
AGRN	HSPG2	ENSPPAP00000016637	ENSPPAP00000037136	Agrin.	Heparan sulfate proteoglycan 2.	0.844
AGRN	LDLR	ENSPPAP00000016637	ENSPPAP00000007978	Agrin.	Low density lipoprotein receptor.	0.529
AGRN	LRP1	ENSPPAP00000016637	ENSPPAP00000012800	Agrin.	LDL receptor related protein 1.	0.616
AGRN	LRP10	ENSPPAP00000016637	ENSPPAP00000012501	Agrin.	LDL receptor related protein 10.	0.443
AGRN	LRP12	ENSPPAP00000016637	ENSPPAP00000034297	Agrin.	LDL receptor related protein 12.	0.443
AGRN	LRP1B	ENSPPAP00000016637	ENSPPAP00000001095	Agrin.	LDL receptor related protein 1B.	0.616
AGRN	LRP2	ENSPPAP00000016637	ENSPPAP00000038526	Agrin.	LDL receptor related protein 2.	0.840
AGRN	LRP3	ENSPPAP00000016637	ENSPPAP00000027644	Agrin.	LDL receptor related protein 3.	0.443
AGRN	LRP8	ENSPPAP00000016637	ENSPPAP00000036567	Agrin.	LDL receptor related protein 8.	0.601
AGRN	SDC1	ENSPPAP00000016637	ENSPPAP00000029236	Agrin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.657
AGRN	SDC3	ENSPPAP00000016637	ENSPPAP00000017786	Agrin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.488
AGRN	SDC4	ENSPPAP00000016637	ENSPPAP00000007506	Agrin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.529
AKR1B10	AKR1C3	ENSPPAP00000018035	ENSPPAP00000010772	Aldo-keto reductase family 1 member B10.	Aldo-keto reductase family 1 member C3.	0.915
AKR1B10	LOC100988315	ENSPPAP00000018035	ENSPPAP00000007230	Aldo-keto reductase family 1 member B10.	Aldo_ket_red domain-containing protein.	0.908