STRINGSTRING
GTF2B GTF2B TAF1L TAF1L POLR2E POLR2E GTF2F1 GTF2F1 TAF1 TAF1 TBPL1 TBPL1 TAF3 TAF3 POLR2F POLR2F TAF12 TAF12 ENSPPAP00000010066 ENSPPAP00000010066 CDK7 CDK7 C11orf88 C11orf88 TAF4 TAF4 GTF2H1 GTF2H1 TAF7L TAF7L GTF2E2 GTF2E2 ERCC2 ERCC2 POLR2A POLR2A ENSPPAP00000034007 ENSPPAP00000034007 GTF2H4 GTF2H4 GTF2H3 GTF2H3 POLR2B POLR2B POLR2K POLR2K TAF11 TAF11 ENSPPAP00000038660 ENSPPAP00000038660 ENSPPAP00000039380 ENSPPAP00000039380 GTF2H5 GTF2H5 TAF15 TAF15 TAF9B TAF9B GTF2E1 GTF2E1 TBP TBP ENSPPAP00000018781 ENSPPAP00000018781 TAF4B TAF4B POLR2I POLR2I MNAT1 MNAT1 CCNH CCNH TAF2 TAF2 POLR2H POLR2H GTF2F2 GTF2F2 ERCC3 ERCC3 TAF10 TAF10 TAF6 TAF6 GTF2H2 GTF2H2 GTF2A2 GTF2A2 GTF2A1 GTF2A1 ENSPPAP00000029844 ENSPPAP00000029844 TAF13 TAF13 TAF5 TAF5 ENSPPAP00000033958 ENSPPAP00000033958 POLR2G POLR2G POLR2C POLR2C POLR2D POLR2D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2BGeneral transcription factor IIB. (348 aa)
TAF1LTranscription initiation factor TFIID subunit. (1825 aa)
POLR2ERNA polymerase II subunit E. (199 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (516 aa)
TAF1Transcription initiation factor TFIID subunit. (1916 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
TAF3PHD-type domain-containing protein. (772 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
TAF12TFIID_20kDa domain-containing protein. (213 aa)
ENSPPAP00000010066Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (91 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
C11orf88Chromosome 11 open reading frame 88. (196 aa)
TAF4TAFH domain-containing protein. (635 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
TAF7LTATA-box binding protein associated factor 7 like. (457 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (2015 aa)
ENSPPAP00000034007Protein kinase domain-containing protein. (324 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
ENSPPAP00000038660TFIIA_gamma_N domain-containing protein. (72 aa)
ENSPPAP00000039380TAFII28 domain-containing protein. (179 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
TAF15Uncharacterized protein. (449 aa)
TAF9BTATA-box binding protein associated factor 9b. (251 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
TBPTATA-box binding protein. (357 aa)
ENSPPAP00000018781Uncharacterized protein. (136 aa)
TAF4BTATA-box binding protein associated factor 4b. (867 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
ENSPPAP00000029844Uncharacterized protein. (229 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
TAF5TATA-box binding protein associated factor 5. (796 aa)
ENSPPAP00000033958Uncharacterized protein. (222 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
POLR2CRNA polymerase II subunit C. (273 aa)
POLR2DRPOL4c domain-containing protein. (110 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.