STRINGSTRING
ENSPPAP00000034007 ENSPPAP00000034007 POLR2D POLR2D ERCC2 ERCC2 POLR2A POLR2A POLR2C POLR2C GTF2H5 GTF2H5 POLR2K POLR2K SUPT5H SUPT5H DUSP11 DUSP11 POLR2B POLR2B GTF2H3 GTF2H3 GTF2H4 GTF2H4 POLR2G POLR2G GTF2H2 GTF2H2 ERCC3 ERCC3 GTF2F2 GTF2F2 POLR2H POLR2H CCNH CCNH C6orf15 C6orf15 MNAT1 MNAT1 POLR2I POLR2I ENSPPAP00000018781 ENSPPAP00000018781 GTF2H1 GTF2H1 CDK7 CDK7 RNGTT RNGTT POLR2F POLR2F RNMT RNMT GTF2F1 GTF2F1 POLR2E POLR2E
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPPAP00000034007Protein kinase domain-containing protein. (324 aa)
POLR2DRPOL4c domain-containing protein. (110 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (2015 aa)
POLR2CRNA polymerase II subunit C. (273 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
SUPT5HTranscription elongation factor SPT5. (1089 aa)
DUSP11Dual specificity phosphatase 11. (377 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
C6orf15Chromosome 6 open reading frame 15. (325 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ENSPPAP00000018781Uncharacterized protein. (136 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (476 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (516 aa)
POLR2ERNA polymerase II subunit E. (199 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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