STRINGSTRING
JAK1 JAK1 SOS1 SOS1 GRB2 GRB2 IL15RA IL15RA SHC1 SHC1 IL2RB IL2RB STAT5B STAT5B IL2RG IL2RG SOS2 SOS2 STAT3 STAT3 STAT5A STAT5A JAK3 JAK3 IL15 IL15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAK1Tyrosine-protein kinase. (1153 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
IL15RASushi domain-containing protein. (278 aa)
SHC1SHC adaptor protein 1. (584 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
JAK3Tyrosine-protein kinase. (1090 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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