STRINGSTRING
SYK SYK HCK HCK LOC100987164 LOC100987164 TYK2 TYK2 STAT1 STAT1 KXD1 KXD1 JAK2 JAK2 SOCS3 SOCS3 JAK1 JAK1 STAT5B STAT5B ELOC ELOC ENSPPAP00000041364 ENSPPAP00000041364 CSF3R CSF3R UBE2D1 UBE2D1 ENSPPAP00000027463 ENSPPAP00000027463 RNF7 RNF7 UBE2D3-2 UBE2D3-2 UBE2D3 UBE2D3 RPS27A RPS27A CUL5 CUL5 ENSPPAP00000022298 ENSPPAP00000022298 LOC100994688 LOC100994688 STAT3 STAT3 UBE2D2 UBE2D2 STAT5A STAT5A LYN LYN LOC100990877 LOC100990877 UBE2D4 UBE2D4 CSF3 CSF3 ELOB ELOB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYKTyrosine-protein kinase. (635 aa)
HCKTyrosine-protein kinase. (526 aa)
LOC100987164Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
KXD1Ubiquitin-like domain-containing protein. (231 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ENSPPAP00000041364annotation not available (140 aa)
CSF3RColony stimulating factor 3 receptor. (836 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSPPAP00000027463UBIQUITIN_CONJUGAT_2 domain-containing protein. (92 aa)
RNF7Ring finger protein 7. (113 aa)
UBE2D3-2Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
RPS27ARibosomal protein S27a. (156 aa)
CUL5Cullin 5; Belongs to the cullin family. (775 aa)
ENSPPAP00000022298Skp1_POZ domain-containing protein. (86 aa)
LOC100994688Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
LYNTyrosine-protein kinase. (526 aa)
LOC100990877Ubiquitin-like domain-containing protein. (156 aa)
UBE2D4UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
CSF3Colony stimulating factor 3. (204 aa)
ELOBUncharacterized protein. (104 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.