STRINGSTRING
TTR TTR LRP1B LRP1B GPC2 GPC2 APOB APOB BCO1 BCO1 GPC3 GPC3 APOC3 APOC3 LPL LPL LOC100988315 LOC100988315 SDC4 SDC4 CLPS CLPS APOA1 APOA1 LDLR LDLR PLB1 PLB1 RBP1 RBP1 AKR1C3 AKR1C3 GPC5 GPC5 LRP10 LRP10 LRP1 LRP1 AGRN AGRN RBP2 RBP2 RETSAT RETSAT SDC3 SDC3 ENSPPAP00000018003 ENSPPAP00000018003 AKR1B10 AKR1B10 AKR1C4 AKR1C4 AKR1C1 AKR1C1 APOM APOM GPIHBP1 GPIHBP1 SDC2 SDC2 APOE APOE LOC103783188 LOC103783188 GPC4 GPC4 ENSPPAP00000027118 ENSPPAP00000027118 GPC1 GPC1 LRP3 LRP3 APOA2 APOA2 RDH11 RDH11 APOA4 APOA4 SDC1 SDC1 GPC6 GPC6 LRP12 LRP12 LRP8 LRP8 BCO2 BCO2 HSPG2 HSPG2 RBP4 RBP4 LRAT LRAT LRP2 LRP2 APOC2 APOC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
LRP1BLDL receptor related protein 1B. (4322 aa)
GPC2Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (508 aa)
APOBApolipoprotein B. (4535 aa)
BCO1Beta-carotene oxygenase 1. (547 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
APOC3Apolipoprotein C3. (99 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
LOC100988315Aldo_ket_red domain-containing protein. (303 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
CLPSColipase. (112 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family. (267 aa)
LDLRLow density lipoprotein receptor. (849 aa)
PLB1Phospholipase B1. (1459 aa)
RBP1Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (323 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
LRP10LDL receptor related protein 10. (715 aa)
LRP1LDL receptor related protein 1. (4544 aa)
AGRNAgrin. (1816 aa)
RBP2Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
RETSATRetinol saturase. (610 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (396 aa)
ENSPPAP00000018003Uncharacterized protein. (3229 aa)
AKR1B10Aldo-keto reductase family 1 member B10. (307 aa)
AKR1C4Aldo-keto reductase family 1 member C4. (323 aa)
AKR1C1Aldo-keto reductase family 1 member C1. (295 aa)
APOMApolipoprotein M. (188 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (184 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
APOEApolipoprotein E. (317 aa)
LOC103783188Aldo_ket_red domain-containing protein. (205 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
ENSPPAP00000027118Uncharacterized protein. (125 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (636 aa)
LRP3LDL receptor related protein 3. (774 aa)
APOA2Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. (133 aa)
RDH11Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
APOA4Apolipoprotein A4. (396 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (334 aa)
GPC6Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (501 aa)
LRP12LDL receptor related protein 12. (845 aa)
LRP8LDL receptor related protein 8. (927 aa)
BCO2Beta-carotene oxygenase 2. (579 aa)
HSPG2Heparan sulfate proteoglycan 2. (4369 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
LRATLecithin retinol acyltransferase. (230 aa)
LRP2LDL receptor related protein 2. (4641 aa)
APOC2Uncharacterized protein. (178 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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