(8 nodes) APOBEC-like C-terminal domain network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AICDA	Activation induced cytidine deaminase. (199 aa)
	APOBEC3H	Apolipoprotein B mRNA editing enzyme catalytic subunit 3H. (200 aa)
	APOBEC2	Apolipoprotein B mRNA editing enzyme catalytic subunit 2. (230 aa)
	APOBEC3B	Uncharacterized protein. (490 aa)
	APOBEC3C	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C. (190 aa)
	APOBEC3G-2	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamin [...] (413 aa)
	APOBEC1	Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (218 aa)
	ENSPPAP00000009967	Uncharacterized protein. (321 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOBEC1	APOBEC2	ENSPPAP00000008823	ENSPPAP00000024923	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.590
APOBEC1	APOBEC3B	ENSPPAP00000008823	ENSPPAP00000002122	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Uncharacterized protein.	0.418
APOBEC1	APOBEC3C	ENSPPAP00000008823	ENSPPAP00000003356	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	0.411
APOBEC1	APOBEC3H	ENSPPAP00000008823	ENSPPAP00000026886	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Apolipoprotein B mRNA editing enzyme catalytic subunit 3H.	0.451
APOBEC2	APOBEC1	ENSPPAP00000024923	ENSPPAP00000008823	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	0.590
APOBEC2	APOBEC3G-2	ENSPPAP00000024923	ENSPPAP00000020141	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamin [...]	0.427
APOBEC3B	APOBEC1	ENSPPAP00000002122	ENSPPAP00000008823	Uncharacterized protein.	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	0.418
APOBEC3B	APOBEC3C	ENSPPAP00000002122	ENSPPAP00000003356	Uncharacterized protein.	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	0.490
APOBEC3B	APOBEC3H	ENSPPAP00000002122	ENSPPAP00000026886	Uncharacterized protein.	Apolipoprotein B mRNA editing enzyme catalytic subunit 3H.	0.602
APOBEC3C	APOBEC1	ENSPPAP00000003356	ENSPPAP00000008823	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	0.411
APOBEC3C	APOBEC3B	ENSPPAP00000003356	ENSPPAP00000002122	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	Uncharacterized protein.	0.490
APOBEC3C	APOBEC3G-2	ENSPPAP00000003356	ENSPPAP00000020141	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamin [...]	0.461
APOBEC3C	APOBEC3H	ENSPPAP00000003356	ENSPPAP00000026886	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	Apolipoprotein B mRNA editing enzyme catalytic subunit 3H.	0.557
APOBEC3G-2	APOBEC2	ENSPPAP00000020141	ENSPPAP00000024923	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamin [...]	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.427
APOBEC3G-2	APOBEC3C	ENSPPAP00000020141	ENSPPAP00000003356	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamin [...]	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	0.461
APOBEC3H	APOBEC1	ENSPPAP00000026886	ENSPPAP00000008823	Apolipoprotein B mRNA editing enzyme catalytic subunit 3H.	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	0.451
APOBEC3H	APOBEC3B	ENSPPAP00000026886	ENSPPAP00000002122	Apolipoprotein B mRNA editing enzyme catalytic subunit 3H.	Uncharacterized protein.	0.602
APOBEC3H	APOBEC3C	ENSPPAP00000026886	ENSPPAP00000003356	Apolipoprotein B mRNA editing enzyme catalytic subunit 3H.	Apolipoprotein B mRNA editing enzyme catalytic subunit 3C.	0.557