STRINGSTRING
MTNR1A MTNR1A MTNR1B MTNR1B PTS PTS MC4R MC4R CALML4 CALML4 GHRH GHRH LEP LEP CALM3 CALM3 LIN28B LIN28B CALML6 CALML6 MT1B MT1B SOCS2 SOCS2 INS-IGF2 INS-IGF2 SOCS3 SOCS3 JAK2 JAK2 CALML5 CALML5 CALML3 CALML3 FTO FTO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (352 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
MC4RMelanocortin 4 receptor. (332 aa)
CALML4Calmodulin like 4. (196 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
LIN28BLin-28 homolog B. (258 aa)
CALML6Calmodulin like 6. (181 aa)
MT1BMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
INS-IGF2INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (200 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
CALML5Calmodulin like 5. (146 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
FTOFTO alpha-ketoglutarate dependent dioxygenase. (559 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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