8 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARNTL	Aryl hydrocarbon receptor nuclear translocator like. (628 aa)
	CISH	Cytokine inducible SH2 containing protein. (275 aa)
	NPAS2	Neuronal PAS domain protein 2. (827 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
	PER3	Period circadian regulator 3. (1211 aa)
	IGF2R	Insulin like growth factor 2 receptor. (2464 aa)
	HBB	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (147 aa)
	SLC22A3	Solute carrier family 22 member 3. (472 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARNTL	CISH	ENSPPAP00000003288	ENSPPAP00000033560	Aryl hydrocarbon receptor nuclear translocator like.	Cytokine inducible SH2 containing protein.	0.517
ARNTL	NPAS2	ENSPPAP00000003288	ENSPPAP00000018292	Aryl hydrocarbon receptor nuclear translocator like.	Neuronal PAS domain protein 2.	0.997
ARNTL	PER3	ENSPPAP00000003288	ENSPPAP00000010052	Aryl hydrocarbon receptor nuclear translocator like.	Period circadian regulator 3.	0.927
CISH	ARNTL	ENSPPAP00000033560	ENSPPAP00000003288	Cytokine inducible SH2 containing protein.	Aryl hydrocarbon receptor nuclear translocator like.	0.517
CISH	HBB	ENSPPAP00000033560	ENSPPAP00000004625	Cytokine inducible SH2 containing protein.	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues.	0.424
CISH	NPAS2	ENSPPAP00000033560	ENSPPAP00000018292	Cytokine inducible SH2 containing protein.	Neuronal PAS domain protein 2.	0.687
CISH	PER3	ENSPPAP00000033560	ENSPPAP00000010052	Cytokine inducible SH2 containing protein.	Period circadian regulator 3.	0.714
CISH	SLC22A3	ENSPPAP00000033560	ENSPPAP00000002171	Cytokine inducible SH2 containing protein.	Solute carrier family 22 member 3.	0.446
EGR1	NPAS2	ENSPPAP00000013439	ENSPPAP00000018292	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Neuronal PAS domain protein 2.	0.430
HBB	CISH	ENSPPAP00000004625	ENSPPAP00000033560	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues.	Cytokine inducible SH2 containing protein.	0.424
HBB	NPAS2	ENSPPAP00000004625	ENSPPAP00000018292	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues.	Neuronal PAS domain protein 2.	0.420
HBB	PER3	ENSPPAP00000004625	ENSPPAP00000010052	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues.	Period circadian regulator 3.	0.424
IGF2R	SLC22A3	ENSPPAP00000005362	ENSPPAP00000002171	Insulin like growth factor 2 receptor.	Solute carrier family 22 member 3.	0.821
NPAS2	ARNTL	ENSPPAP00000018292	ENSPPAP00000003288	Neuronal PAS domain protein 2.	Aryl hydrocarbon receptor nuclear translocator like.	0.997
NPAS2	CISH	ENSPPAP00000018292	ENSPPAP00000033560	Neuronal PAS domain protein 2.	Cytokine inducible SH2 containing protein.	0.687
NPAS2	EGR1	ENSPPAP00000018292	ENSPPAP00000013439	Neuronal PAS domain protein 2.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.430
NPAS2	HBB	ENSPPAP00000018292	ENSPPAP00000004625	Neuronal PAS domain protein 2.	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues.	0.420
NPAS2	PER3	ENSPPAP00000018292	ENSPPAP00000010052	Neuronal PAS domain protein 2.	Period circadian regulator 3.	0.876
NPAS2	SLC22A3	ENSPPAP00000018292	ENSPPAP00000002171	Neuronal PAS domain protein 2.	Solute carrier family 22 member 3.	0.405
PER3	ARNTL	ENSPPAP00000010052	ENSPPAP00000003288	Period circadian regulator 3.	Aryl hydrocarbon receptor nuclear translocator like.	0.927