STRINGSTRING
SPHK1 SPHK1 CALML3 CALML3 DHFR DHFR DNMT1 DNMT1 SLC20A2 SLC20A2 HSF1 HSF1 SLC20A1 SLC20A1 DLX6 DLX6 DLX5 DLX5 AGO4 AGO4 CALML4 CALML4 MECP2 MECP2 KCNQ1 KCNQ1 IGF2 IGF2 YY1 YY1 CALM3 CALM3 DROSHA DROSHA BACE1 BACE1 CALML6 CALML6 CTCF CTCF HNRNPK HNRNPK UPF1 UPF1 SLC22A3 SLC22A3 JARID2 JARID2 SLC22A2 SLC22A2 CEBPA CEBPA IGF2R IGF2R CALML5 CALML5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPHK1Sphingosine kinase 1. (470 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
DHFRDihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1637 aa)
SLC20A2Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (651 aa)
HSF1Heat shock transcription factor 1. (490 aa)
SLC20A1Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (679 aa)
DLX6Homeobox domain-containing protein. (165 aa)
DLX5Distal-less homeobox 5. (289 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
CALML4Calmodulin like 4. (196 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (493 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
IGF2Insulin like growth factor 2. (236 aa)
YY1Uncharacterized protein. (370 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
DROSHADrosha ribonuclease III. (1369 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
CALML6Calmodulin like 6. (181 aa)
CTCFCCCTC-binding factor. (727 aa)
HNRNPKUncharacterized protein. (477 aa)
UPF1UPF1 RNA helicase and ATPase. (1096 aa)
SLC22A3Solute carrier family 22 member 3. (472 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1224 aa)
SLC22A2Solute carrier family 22 member 2. (555 aa)
CEBPABZIP domain-containing protein. (141 aa)
IGF2RInsulin like growth factor 2 receptor. (2464 aa)
CALML5Calmodulin like 5. (146 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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