STRINGSTRING
CD19 CD19 BCR BCR OAS1 OAS1 IRF7 IRF7 ISG15 ISG15 MX1 MX1 CD4 CD4 CD38 CD38 CD27 CD27 CD22 CD22 STAT1 STAT1 STAT2 STAT2 IFNG IFNG IL15 IL15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD19CD19 molecule. (545 aa)
BCRUncharacterized protein. (1034 aa)
OAS12',5'-oligoadenylate synthetase 1. (401 aa)
IRF7Interferon regulatory factor 7. (516 aa)
ISG15ISG15 ubiquitin like modifier. (165 aa)
MX1Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (662 aa)
CD4CD4 molecule. (458 aa)
CD38CD38 molecule. (300 aa)
CD27CD27 molecule. (260 aa)
CD22B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
STAT2Signal transducer and activator of transcription. (853 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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