STRINGSTRING
IFIT1 IFIT1 HKDC1 HKDC1 MX1 MX1 IFITM1 IFITM1 AKR1B10 AKR1B10 IFIT3 IFIT3 ISG15 ISG15 UBA7 UBA7 IDO1 IDO1 ISG20 ISG20 IRF1 IRF1 PSMA6 PSMA6 CCL5 CCL5 IFNG IFNG HLA-DMA HLA-DMA INS-IGF2 INS-IGF2 GAPDH GAPDH RSAD2 RSAD2 CCL18 CCL18 CXCL10 CXCL10 TRIM22 TRIM22
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFIT1Interferon induced protein with tetratricopeptide repeats 1. (476 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
MX1Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (662 aa)
IFITM1Interferon induced transmembrane protein 1. (125 aa)
AKR1B10Aldo-keto reductase family 1 member B10. (307 aa)
IFIT3Interferon induced protein with tetratricopeptide repeats 3. (490 aa)
ISG15ISG15 ubiquitin like modifier. (165 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1012 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
ISG20Interferon stimulated exonuclease gene 20. (179 aa)
IRF1Interferon regulatory factor. (325 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
CCL5C-C motif chemokine. (91 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (268 aa)
INS-IGF2INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (200 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (361 aa)
CCL18C-C motif chemokine. (89 aa)
CXCL10C-X-C motif chemokine. (96 aa)
TRIM22Tripartite motif containing 22. (498 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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