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| | SRC | Tyrosine-protein kinase. (458 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | LIMK1 | LIM domain kinase 1. (677 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | NGF | NGF domain-containing protein; Belongs to the NGF-beta family. (123 aa) |
| | GPX5 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (224 aa) |
| | MPO | Myeloperoxidase. (745 aa) |
| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (214 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGF14 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (296 aa) |
| | SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) |
| | BACE1 | Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa) |
| | GPX7 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (171 aa) |
| | CALM3 | Calmodulin 3; Belongs to the calmodulin family. (149 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa) |
| | IL6 | Uncharacterized protein. (198 aa) |
| | PARVG | Parvin gamma. (331 aa) |
| | DCX | Doublecortin. (420 aa) |
| | FGF12 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa) |
| | GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa) |
| | EXOSC2 | Exosome component 2. (293 aa) |
| | FGF11 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa) |
| | CALML4 | Calmodulin like 4. (196 aa) |
| | SYP | Synaptophysin. (313 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1196 aa) |
| | GPX3 | Uncharacterized protein. (72 aa) |
| | BCL2 | BCL2 apoptosis regulator. (193 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | GPX6 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (220 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | POMT2 | Protein O-mannosyltransferase 2. (750 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (521 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
| | UBL3 | Ubiquitin-like protein. (117 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa) |
| | TRIM45 | Tripartite motif containing 45. (577 aa) |
| | RPL35 | Ribosomal protein L35. (123 aa) |
| | SIRT1 | Sirtuin 1. (693 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | SNCA | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa) |
| | CALML5 | Calmodulin like 5. (146 aa) |
| | ENSPPAP00000004900 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa) |
| | FOXG1 | Uncharacterized protein. (151 aa) |
| | IGF1 | IlGF domain-containing protein. (196 aa) |
| | TIRAP | TIR domain-containing protein. (226 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | GPX2 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | ARC | Activity regulated cytoskeleton associated protein. (396 aa) |
| | NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1403 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa) |
| | ALB | Albumin. (609 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa) |
| | GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (200 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (260 aa) |
| | HES3 | Hes family bHLH transcription factor 3. (185 aa) |
| | ENSPPAP00000036267 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (139 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa) |
