STRINGSTRING
STAT3 STAT3 NR1H4 NR1H4 OSM OSM STAT6 STAT6 SLC10A7 SLC10A7 CALML4 CALML4 IL6 IL6 PRL PRL SLC10A3 SLC10A3 FGFR4 FGFR4 CALM3 CALM3 KIF4A KIF4A STAT4 STAT4 STAT1 STAT1 STAT5B STAT5B CALML6 CALML6 STAT2 STAT2 IFNG IFNG STAT5A STAT5A SLC10A4 SLC10A4 EGFR EGFR SIRT1 SIRT1 CALML3 CALML3 CALML5 CALML5 KLB KLB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT3Signal transducer and activator of transcription. (781 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (482 aa)
OSMOncostatin M. (252 aa)
STAT6Signal transducer and activator of transcription. (852 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (358 aa)
CALML4Calmodulin like 4. (196 aa)
IL6Uncharacterized protein. (198 aa)
PRLProlactin. (227 aa)
SLC10A3Solute carrier family 10 member 3. (532 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1229 aa)
STAT4Signal transducer and activator of transcription. (742 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
CALML6Calmodulin like 6. (181 aa)
STAT2Signal transducer and activator of transcription. (853 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
SLC10A4Solute carrier family 10 member 4. (377 aa)
EGFRReceptor protein-tyrosine kinase. (1201 aa)
SIRT1Sirtuin 1. (693 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin like 5. (146 aa)
KLBKlotho beta. (1044 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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