STRINGSTRING
IL6 IL6 VGLL4 VGLL4 LMCD1 LMCD1 CLOCK CLOCK IDO1 IDO1 PER3 PER3 PSTPIP2 PSTPIP2 TNF TNF ARNTL ARNTL KYNU KYNU HAAO HAAO SLC9A1 SLC9A1 PER2 PER2 FBN1 FBN1 IFNG IFNG IDO2 IDO2 TH TH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL6Uncharacterized protein. (198 aa)
VGLL4Vestigial like family member 4. (296 aa)
LMCD1Uncharacterized protein. (292 aa)
CLOCKClock circadian regulator. (847 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
PER3Period circadian regulator 3. (1211 aa)
PSTPIP2Proline-serine-threonine phosphatase interacting protein 2. (334 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
PER2Period circadian regulator 2. (1255 aa)
FBN1Fibrillin 1. (2871 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
IDO2Indoleamine 2,3-dioxygenase 2. (376 aa)
THTyrosine hydroxylase. (528 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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