STRINGSTRING
LOC100990759 LOC100990759 EGF EGF CLEC14A CLEC14A MATN1 MATN1 VASN VASN NCAN NCAN LRP1B LRP1B CNTNAP4 CNTNAP4 TMEFF2 TMEFF2 RSPO3 RSPO3 UMODL1 UMODL1 CRELD2 CRELD2 ENSPPAP00000003405 ENSPPAP00000003405 PLAT PLAT FBLN2 FBLN2 F12 F12 MEP1B MEP1B NOTCH3 NOTCH3 TENM1 TENM1 THBD THBD THBS1 THBS1 HGFAC HGFAC HMCN1 HMCN1 ITGB5 ITGB5 SLIT1 SLIT1 PAMR1 PAMR1 TMEM8B TMEM8B VCAN VCAN DLK2 DLK2 MEGF6 MEGF6 MEGF8 MEGF8 PROS1 PROS1 SORL1 SORL1 PTGS1 PTGS1 MFGE8 MFGE8 ENSPPAP00000008808 ENSPPAP00000008808 ADAM2 ADAM2 ATRN ATRN LRP5 LRP5 DLL4 DLL4 CNTNAP2 CNTNAP2 OIT3 OIT3 CELSR2 CELSR2 EFEMP2 EFEMP2 SUSD1 SUSD1 MEP1A MEP1A LTBP4 LTBP4 VLDLR VLDLR HYAL2 HYAL2 LRP1 LRP1 NRG1 NRG1 EGFL6 EGFL6 IMPG1 IMPG1 NRXN2 NRXN2 LOC100987604 LOC100987604 ADAM22 ADAM22 NOTCH2 NOTCH2 ADAM23 ADAM23 CNTNAP1 CNTNAP1 NOTCH4 NOTCH4 WIF1 WIF1 SVEP1 SVEP1 CRB2 CRB2 ADAM9 ADAM9 TDGF1 TDGF1 JAG2 JAG2 GAS6 GAS6 CNTNAP5 CNTNAP5 CELSR3 CELSR3 FBLN7 FBLN7 CCBE1 CCBE1 FBN3 FBN3 AGRN AGRN HABP2 HABP2 NELL2 NELL2 LOC100967790 LOC100967790 FBLN1 FBLN1 NRXN3 NRXN3 CUBN CUBN SELL SELL FAT4 FAT4 HHIP HHIP BTC BTC NRG4 NRG4 ATRNL1 ATRNL1 FAT1 FAT1 SLIT3 SLIT3 TNC TNC ENSPPAP00000020734 ENSPPAP00000020734 ADGRE1 ADGRE1 SELP SELP NRG3 NRG3 SCARF1 SCARF1 VWA2 VWA2 NID2 NID2 ADAM11 ADAM11 ADAM32 ADAM32 NID1 NID1 TEK TEK TMEFF1 TMEFF1 NPNT NPNT EGFLAM EGFLAM PROZ PROZ JAG1 JAG1 SCUBE2 SCUBE2 LRP6 LRP6 VWCE VWCE RELN RELN EDIL3 EDIL3 THBS4 THBS4 MATN2 MATN2 TECTA TECTA F10 F10 NRG2 NRG2 ADAM28 ADAM28 MATN3 MATN3 FAT2 FAT2 PEAR1 PEAR1 MATN4 MATN4 ITGBL1 ITGBL1 TENM2 TENM2 PLAU PLAU HYAL3 HYAL3 NTNG2 NTNG2 ASTN1 ASTN1 ATRAID ATRAID LTBP3 LTBP3 TIE1 TIE1 CRB1 CRB1 VWDE VWDE DLL1 DLL1 SNED1 SNED1 LTBP1 LTBP1 DNER DNER LTBP2 LTBP2 NELL1 NELL1 HYAL1 HYAL1 CELSR1 CELSR1 UMOD UMOD SCARF2 SCARF2 MEGF10 MEGF10 STAB1 STAB1 TENM3 TENM3 ADAM15 ADAM15 ZAN ZAN NAGPA NAGPA PROC PROC EGFL7 EGFL7 ACAN ACAN PGAP6 PGAP6 F7 F7 BCAN BCAN GPR179 GPR179 NOTCH1 NOTCH1 HBEGF HBEGF TNN TNN F9 F9 THBS2 THBS2 ADAM33 ADAM33 CD93 CD93 NRXN1 NRXN1 MUC13 MUC13 DLL3 DLL3 COMP COMP SELE SELE FBN2 FBN2 LRP8 LRP8 HEG1 HEG1 HSPG2 HSPG2 TENM4 TENM4 CSPG5 CSPG5 CD248 CD248 DLK1 DLK1 LRP2 LRP2 FAT3 FAT3 LOC100992963 LOC100992963 FBN1 FBN1 AREG AREG MMRN1 MMRN1 EREG EREG TGFA TGFA STAB2 STAB2 PTGS2 PTGS2 ADAM8 ADAM8 LRP4 LRP4 LDLR LDLR SCUBE1 SCUBE1 BRINP2 BRINP2 MEGF11 MEGF11 BRINP3 BRINP3 NTNG1 NTNG1 SCUBE3 SCUBE3 SLIT2 SLIT2 LOC100988948 LOC100988948 ITGB8 ITGB8 ADGRE2 ADGRE2 THBS3 THBS3 ADGRL4 ADGRL4 HYAL4 HYAL4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100990759EGF-like domain-containing protein. (223 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
CLEC14AC-type lectin domain containing 14A. (490 aa)
MATN1Matrilin 1. (496 aa)
VASNVasorin. (673 aa)
NCANNeurocan. (1321 aa)
LRP1BLDL receptor related protein 1B. (4322 aa)
CNTNAP4Uncharacterized protein. (1308 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
RSPO3R-spondin 3. (291 aa)
UMODL1Uromodulin like 1. (1434 aa)
CRELD2Cysteine rich with EGF like domains 2. (364 aa)
ENSPPAP00000003405Uncharacterized protein. (717 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
FBLN2Fibulin 2. (1231 aa)
F12Coagulation factor XII. (615 aa)
MEP1BMeprin A subunit. (701 aa)
NOTCH3Notch receptor 3. (1981 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
THBDThrombomodulin. (631 aa)
THBS1Thrombospondin 1. (1173 aa)
HGFACHGF activator. (662 aa)
HMCN1Hemicentin 1. (5622 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (803 aa)
SLIT1Slit guidance ligand 1. (1533 aa)
PAMR1Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (737 aa)
TMEM8BTransmembrane protein 8B. (472 aa)
VCANVersican. (3396 aa)
DLK2Delta like non-canonical Notch ligand 2. (383 aa)
MEGF6Uncharacterized protein. (1390 aa)
MEGF8Multiple EGF like domains 8. (2845 aa)
PROS1Protein S. (675 aa)
SORL1Sortilin related receptor 1. (2214 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (387 aa)
ENSPPAP00000008808Uncharacterized protein. (718 aa)
ADAM2ADAM metallopeptidase domain 2. (735 aa)
ATRNAttractin. (1317 aa)
LRP5LDL receptor related protein 5. (1839 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
OIT3Oncoprotein induced transcript 3. (557 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2908 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
SUSD1Sushi domain containing 1. (688 aa)
MEP1AMeprin A subunit. (762 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1622 aa)
VLDLRVery low density lipoprotein receptor. (1038 aa)
HYAL2Hyaluronidase. (473 aa)
LRP1LDL receptor related protein 1. (4544 aa)
NRG1Neuregulin 1. (645 aa)
EGFL6EGF like domain multiple 6. (553 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (800 aa)
NRXN2Neurexin 2. (1671 aa)
LOC100987604Uncharacterized protein. (386 aa)
ADAM22ADAM metallopeptidase domain 22. (889 aa)
NOTCH2Notch receptor 2. (2254 aa)
ADAM23ADAM metallopeptidase domain 23. (788 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
NOTCH4Notch receptor 4. (2001 aa)
WIF1WNT inhibitory factor 1. (379 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3571 aa)
CRB2Crumbs cell polarity complex component 2. (1083 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1099 aa)
GAS6Growth arrest specific 6. (679 aa)
CNTNAP5Contactin associated protein like 5. (1307 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3324 aa)
FBLN7Fibulin 7. (439 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
FBN3Fibrillin 3. (2809 aa)
AGRNAgrin. (1816 aa)
HABP2Hyaluronan binding protein 2. (560 aa)
NELL2Neural EGFL like 2. (866 aa)
LOC100967790Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (663 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (720 aa)
NRXN3Neurexin 3. (1664 aa)
CUBNCubilin. (3623 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
FAT4FAT atypical cadherin 4. (4983 aa)
HHIPHedgehog interacting protein. (700 aa)
BTCBetacellulin. (178 aa)
NRG4Neuregulin 4. (117 aa)
ATRNL1Attractin like 1. (1379 aa)
FAT1FAT atypical cadherin 1. (4588 aa)
SLIT3Slit guidance ligand 3. (1527 aa)
TNCTenascin C. (2201 aa)
ENSPPAP00000020734Uncharacterized protein. (622 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (886 aa)
SELPSelectin P. (830 aa)
NRG3Neuregulin 3. (719 aa)
SCARF1Scavenger receptor class F member 1. (830 aa)
VWA2Von Willebrand factor A domain containing 2. (712 aa)
NID2Nidogen 2. (1386 aa)
ADAM11ADAM metallopeptidase domain 11. (780 aa)
ADAM32ADAM metallopeptidase domain 32. (787 aa)
NID1Nidogen 1. (1247 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
TMEFF1Uncharacterized protein. (454 aa)
NPNTNephronectin. (612 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (984 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (422 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (980 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
VWCEVon Willebrand factor C and EGF domains. (955 aa)
RELNReelin. (3460 aa)
EDIL3EGF like repeats and discoidin domains 3. (488 aa)
THBS4Thrombospondin 4. (870 aa)
MATN2Matrilin 2. (956 aa)
TECTATectorin alpha. (2155 aa)
F10Coagulation factor X. (488 aa)
NRG2Uncharacterized protein. (705 aa)
ADAM28ADAM metallopeptidase domain 28. (797 aa)
MATN3Matrilin 3. (486 aa)
FAT2FAT atypical cadherin 2. (4348 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1029 aa)
MATN4Matrilin 4. (622 aa)
ITGBL1Integrin subunit beta like 1. (409 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
PLAUPlasminogen activator, urokinase. (431 aa)
HYAL3Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa)
NTNG2Netrin G2. (530 aa)
ASTN1Astrotactin 1. (1260 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1270 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
VWDEUncharacterized protein. (1275 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (624 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1352 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1690 aa)
DNERDelta/notch like EGF repeat containing. (645 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1813 aa)
NELL1Neural EGFL like 1. (838 aa)
HYAL1Hyaluronidase. (435 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2933 aa)
UMODUromodulin. (681 aa)
SCARF2Uncharacterized protein. (717 aa)
MEGF10Multiple EGF like domains 10. (1140 aa)
STAB1Stabilin 1. (2570 aa)
TENM3Teneurin transmembrane protein 3. (2703 aa)
ADAM15ADAM metallopeptidase domain 15. (863 aa)
ZANUncharacterized protein. (2336 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (498 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (461 aa)
EGFL7EGF like domain multiple 7. (273 aa)
ACANAggrecan. (2106 aa)
PGAP6Transmembrane protein 8A. (771 aa)
F7Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity). Belongs to the peptidase S1 family. (444 aa)
BCANBrevican. (907 aa)
GPR179G protein-coupled receptor 179. (2366 aa)
NOTCH1Notch receptor 1. (2573 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
TNNTenascin N. (1299 aa)
F9Coagulation factor IX. (486 aa)
THBS2Thrombospondin 2. (1172 aa)
ADAM33ADAM metallopeptidase domain 33. (817 aa)
CD93CD93 molecule. (650 aa)
NRXN1Neurexin 1. (1445 aa)
MUC13Mucin 13, cell surface associated. (496 aa)
DLL3Uncharacterized protein. (493 aa)
COMPCartilage oligomeric matrix protein. (762 aa)
SELESelectin E. (612 aa)
FBN2Fibrillin 2. (2866 aa)
LRP8LDL receptor related protein 8. (927 aa)
HEG1Heart development protein with EGF like domains 1. (1275 aa)
HSPG2Heparan sulfate proteoglycan 2. (4369 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (562 aa)
CD248CD248 molecule. (726 aa)
DLK1Delta like non-canonical Notch ligand 1. (419 aa)
LRP2LDL receptor related protein 2. (4641 aa)
FAT3Uncharacterized protein. (892 aa)
LOC100992963Uncharacterized protein. (3854 aa)
FBN1Fibrillin 1. (2871 aa)
AREGEGF-like domain-containing protein. (274 aa)
MMRN1Multimerin 1. (1226 aa)
EREGEpiregulin. (169 aa)
TGFATransforming growth factor alpha. (181 aa)
STAB2Stabilin 2. (2551 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ADAM8ADAM metallopeptidase domain 8. (816 aa)
LRP4LDL receptor related protein 4. (1857 aa)
LDLRLow density lipoprotein receptor. (849 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (992 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (783 aa)
MEGF11Multiple EGF like domains 11. (990 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
NTNG1Netrin G1. (539 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
SLIT2Slit guidance ligand 2. (1410 aa)
LOC100988948Uncharacterized protein. (699 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (757 aa)
ADGRE2Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (764 aa)
THBS3Thrombospondin 3. (956 aa)
ADGRL4Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (691 aa)
HYAL4Hyaluronidase. (481 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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