STRINGSTRING
RIMS4 RIMS4 RGS3 RGS3 CAPN5 CAPN5 CCDC33 CCDC33 PLA2G4F PLA2G4F PRKCB PRKCB RASAL1 RASAL1 RPGRIP1 RPGRIP1 SYT16 SYT16 SYT4 SYT4 SYT2 SYT2 DYSF DYSF RPH3A RPH3A WWP1 WWP1 SYNGAP1 SYNGAP1 RASA2 RASA2 UNC13B UNC13B PLCD3 PLCD3 CADPS CADPS C2CD5 C2CD5 SYT3 SYT3 SYT8 SYT8 OTOF OTOF DAB2IP DAB2IP PIK3C2A PIK3C2A ENSPPAP00000032614 ENSPPAP00000032614 PKN1 PKN1 SYT11 SYT11 CPNE9 CPNE9 RPGRIP1L RPGRIP1L PLCG2 PLCG2 PLA2G4D PLA2G4D CC2D2A CC2D2A PLCD4 PLCD4 PLCB2 PLCB2 RIMS3 RIMS3 RIMS2 RIMS2 PLCB3 PLCB3 MYOF MYOF CPNE6 CPNE6 ITSN1 ITSN1 RIMS1 RIMS1 PRF1 PRF1 SYT9 SYT9 SYT7 SYT7 ESYT2 ESYT2 SYTL5 SYTL5 PLCL1 PLCL1 SYT15 SYT15 C2CD3 C2CD3 SMURF2 SMURF2 PIK3C2G PIK3C2G LOC103783902 LOC103783902 RASAL2 RASAL2 PLA2G4A PLA2G4A PKN3 PKN3 ITCH ITCH SYT10 SYT10 SYTL3 SYTL3 CPNE8 CPNE8 MCTP1 MCTP1 MCTP2 MCTP2 C2CD4C C2CD4C C2CD2 C2CD2 SYDE2 SYDE2 CPNE5 CPNE5 CC2D1B CC2D1B SYTL1 SYTL1 CC2D1A CC2D1A PLCL2 PLCL2 RAB11FIP2 RAB11FIP2 PLCH1 PLCH1 CPNE2 CPNE2 UNC13D UNC13D ESYT3 ESYT3 CPNE4 CPNE4 PLCB1 PLCB1 C2CD2L C2CD2L PLCB4 PLCB4 SYT17 SYT17 WWP2 WWP2 PLCD1 PLCD1 SYTL4 SYTL4 SYT13 SYT13 UVRAG UVRAG CAPN6 CAPN6 PIK3CA PIK3CA CPNE3 CPNE3 PLA2G4E PLA2G4E UNC13C UNC13C FER1L5 FER1L5 SYT1 SYT1 TOLLIP TOLLIP PKN2 PKN2 SYT12 SYT12 PRKCG PRKCG BAIAP3 BAIAP3 ABR ABR CADPS2 CADPS2 INPP4A INPP4A UNC13A UNC13A TC2N TC2N SYT14 SYT14 HECW1 HECW1 PIK3C2B PIK3C2B FER1L6 FER1L6 RASA1 RASA1 SYTL2 SYTL2 PRKCA PRKCA SYT5 SYT5 SMURF1 SMURF1 PLCG1 PLCG1 ITSN2 ITSN2 DOC2A DOC2A CEP120 CEP120 PLCH2 PLCH2 RASA3 RASA3 PRKCE PRKCE CPNE7 CPNE7 PLCE1 PLCE1 PLCZ1 PLCZ1 PRKCH PRKCH PRKCD PRKCD SYT6 SYT6 DOC2B DOC2B ESYT1 ESYT1 HECW2 HECW2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIMS4Regulating synaptic membrane exocytosis 4. (265 aa)
RGS3Regulator of G protein signaling 3. (1174 aa)
CAPN5Calpain 5; Belongs to the peptidase C2 family. (680 aa)
CCDC33Coiled-coil domain containing 33. (755 aa)
PLA2G4FPhospholipase A2. (849 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
RASAL1RAS protein activator like 1. (806 aa)
RPGRIP1RPGR interacting protein 1. (1239 aa)
SYT16C2 domain-containing protein. (203 aa)
SYT4Synaptotagmin 4. (425 aa)
SYT2Synaptotagmin 2. (419 aa)
DYSFDysferlin. (2119 aa)
RPH3ARabphilin 3A. (694 aa)
WWP1E3 ubiquitin-protein ligase. (922 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1346 aa)
RASA2RAS p21 protein activator 2. (929 aa)
UNC13BUncharacterized protein. (4343 aa)
PLCD3Phosphoinositide phospholipase C. (737 aa)
CADPSUncharacterized protein. (1293 aa)
C2CD5C2 calcium dependent domain containing 5. (1084 aa)
SYT3Synaptotagmin 3. (590 aa)
SYT8Synaptotagmin 8. (387 aa)
OTOFOtoferlin. (1996 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
ENSPPAP00000032614C2 domain-containing protein. (356 aa)
PKN1Protein kinase N1. (948 aa)
SYT11Synaptotagmin 11. (431 aa)
CPNE9Copine family member 9. (550 aa)
RPGRIP1LRPGRIP1 like. (1309 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PLA2G4DPhospholipase A2. (818 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1627 aa)
PLCD4Phosphoinositide phospholipase C. (794 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
RIMS2Uncharacterized protein. (1356 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
MYOFMyoferlin. (2061 aa)
CPNE6Copine 6. (612 aa)
ITSN1Intersectin 1. (1720 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
PRF1Perforin 1. (555 aa)
SYT9Synaptotagmin 9. (491 aa)
SYT7Uncharacterized protein. (686 aa)
ESYT2Extended synaptotagmin 2. (809 aa)
SYTL5Synaptotagmin like 5. (752 aa)
PLCL1Phosphoinositide phospholipase C. (1047 aa)
SYT15C2 domain-containing protein. (311 aa)
C2CD3Uncharacterized protein. (1886 aa)
SMURF2E3 ubiquitin-protein ligase. (790 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1468 aa)
LOC103783902Uncharacterized protein. (2047 aa)
RASAL2RAS protein activator like 2. (1279 aa)
PLA2G4APhospholipase A2. (749 aa)
PKN3Protein kinase N3. (869 aa)
ITCHE3 ubiquitin-protein ligase. (870 aa)
SYT10Synaptotagmin 10. (523 aa)
SYTL3Synaptotagmin like 3. (610 aa)
CPNE8Copine 8. (564 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (953 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (934 aa)
C2CD4CC2 calcium dependent domain containing 4C. (421 aa)
C2CD2C2 calcium dependent domain containing 2. (634 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1194 aa)
CPNE5Copine 5. (582 aa)
CC2D1BCoiled-coil and C2 domain containing 1B. (858 aa)
SYTL1Synaptotagmin like 1. (562 aa)
CC2D1AUncharacterized protein. (700 aa)
PLCL2Phosphoinositide phospholipase C. (1101 aa)
RAB11FIP2RAB11 family interacting protein 2. (512 aa)
PLCH1Phosphoinositide phospholipase C. (1693 aa)
CPNE2Copine 2. (548 aa)
UNC13DUnc-13 homolog D. (1079 aa)
ESYT3Extended synaptotagmin 3. (886 aa)
CPNE4Copine 4. (575 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
C2CD2LC2CD2 like. (706 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
SYT17Synaptotagmin 17. (474 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
PLCD1Phosphoinositide phospholipase C. (781 aa)
SYTL4Synaptotagmin like 4. (671 aa)
SYT13Synaptotagmin 13. (426 aa)
UVRAGUV radiation resistance associated. (698 aa)
CAPN6Calpain 6; Belongs to the peptidase C2 family. (641 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
CPNE3Copine 3. (537 aa)
PLA2G4EPhospholipase A2. (868 aa)
UNC13CC2 domain-containing protein. (135 aa)
FER1L5Fer-1 like family member 5. (2093 aa)
SYT1Synaptotagmin 1. (422 aa)
TOLLIPCUE domain-containing protein. (364 aa)
PKN2Protein kinase N2. (976 aa)
SYT12Synaptotagmin 12. (420 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
BAIAP3BAI1 associated protein 3. (1171 aa)
ABRABR activator of RhoGEF and GTPase. (874 aa)
CADPS2Calcium dependent secretion activator 2. (1296 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (977 aa)
UNC13AUnc-13 homolog A. (1628 aa)
TC2NTandem C2 domains, nuclear. (490 aa)
SYT14C2 domain-containing protein. (864 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1602 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1635 aa)
FER1L6Fer-1 like family member 6. (1857 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
SYTL2Uncharacterized protein. (2223 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
SYT5Synaptotagmin 5. (408 aa)
SMURF1E3 ubiquitin-protein ligase. (752 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1248 aa)
ITSN2Intersectin 2. (1693 aa)
DOC2ADouble C2-like domain-containing protein. (400 aa)
CEP120Centrosomal protein 120. (986 aa)
PLCH2Phosphoinositide phospholipase C. (1415 aa)
RASA3RAS p21 protein activator 3. (834 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CPNE7Copine 7. (591 aa)
PLCE1Phosphoinositide phospholipase C. (2276 aa)
PLCZ1Phosphoinositide phospholipase C. (639 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
SYT6Uncharacterized protein. (539 aa)
DOC2BUncharacterized protein. (360 aa)
ESYT1Extended synaptotagmin 1. (1114 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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