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| | PFKP | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa) |
| | ENO1 | Enolase 1. (434 aa) |
| | PGK2 | Phosphoglycerate kinase. (417 aa) |
| | ACOX3 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa) |
| | GCSH | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (123 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (370 aa) |
| | ACADS | Acyl-CoA dehydrogenase short chain. (412 aa) |
| | ACO2 | Aconitase 2. (800 aa) |
| | GLUD1 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (267 aa) |
| | MCEE | Methylmalonyl-CoA epimerase. (176 aa) |
| | LOC100972512 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa) |
| | TKTL2 | Transketolase like 2. (722 aa) |
| | GLUD2 | ELFV_dehydrog domain-containing protein. (162 aa) |
| | IDNK | Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (187 aa) |
| | ME3 | Malic enzyme. (545 aa) |
| | HAO2 | Hydroxyacid oxidase 2. (351 aa) |
| | PGLS | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (258 aa) |
| | AGXT | Serine--pyruvate aminotransferase. (392 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (670 aa) |
| | TKFC | Triokinase and FMN cyclase. (576 aa) |
| | TKTL1 | Transket_pyr domain-containing protein. (603 aa) |
| | PFKL | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (771 aa) |
| | PGAM1 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa) |
| | IDH3B | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (408 aa) |
| | PGP | Uncharacterized protein. (122 aa) |
| | ADH5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (383 aa) |
| | SDHC | Succinate dehydrogenase complex subunit C. (169 aa) |
| | ESD | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa) |
| | FH | Fumarate hydratase. (510 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa) |
| | ALDH6A1 | Aldehyde dehydrogenase 6 family member A1. (535 aa) |
| | GCK | Phosphotransferase. (463 aa) |
| | SUCLG1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (336 aa) |
| | DLST | Dihydrolipoamide S-succinyltransferase. (453 aa) |
| | SDS | Serine dehydratase. (328 aa) |
| | IDH2 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (428 aa) |
| | TKT | Transketolase. (631 aa) |
| | LOC100971459 | Phosphoglycerate kinase. (417 aa) |
| | PGAM2 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa) |
| | PDHA1 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (463 aa) |
| | TALDO1 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa) |
| | ACO1 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa) |
| | MDH2 | Malate dehydrogenase. (338 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa) |
| | FBP2 | Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa) |
| | DLD | Dihydrolipoyl dehydrogenase. (538 aa) |
| | LOC100973698 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (712 aa) |
| | HIBCH | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (297 aa) |
| | RPE | Uncharacterized protein. (252 aa) |
| | PRPS2 | Phosphoribosyl pyrophosphate synthetase 2. (321 aa) |
| | MMUT | Methylmalonyl-CoA mutase. (750 aa) |
| | RGN | Regucalcin. (299 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa) |
| | ENO4 | Enolase 4. (628 aa) |
| | HKDC1 | Hexokinase domain containing 1. (917 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (668 aa) |
| | OGDHL | Oxoglutarate dehydrogenase like. (1012 aa) |
| | SUCLG2 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (433 aa) |
| | ECHS1 | Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa) |
| | LOC100976996 | Phosphoglycerate kinase. (408 aa) |
| | ACOX1 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa) |
| | ME2 | Malic enzyme. (584 aa) |
| | GPT2 | Glutamic--pyruvic transaminase 2. (523 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (428 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) |
| | CS | Citrate synthase; Belongs to the citrate synthase family. (466 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | PCCA | Propionyl-CoA carboxylase subunit alpha. (728 aa) |
| | HK3 | Hexokinase 3. (923 aa) |
| | SUCLA2 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (463 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1510 aa) |
| | PFKM | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa) |
| | ALDOB | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa) |
| | PGD | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa) |
| | ADPGK | ADP dependent glucokinase. (497 aa) |
| | HK2 | Hexokinase 2. (917 aa) |
| | PC | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa) |
| | AMT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa) |
| | ALDOA | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (729 aa) |
| | ENO3 | Enolase 3. (434 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (335 aa) |
| | ENO2 | Enolase 2. (434 aa) |
| | GPI | Glucose-6-phosphate isomerase; Belongs to the GPI family. (625 aa) |
| | HK1 | Hexokinase 1. (921 aa) |
| | SDSL | Serine dehydratase like. (329 aa) |
| | PHGDH | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (573 aa) |
| | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | OGDH | Oxoglutarate dehydrogenase. (1038 aa) |
| | IDH3A | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (373 aa) |
| | PKM | Pyruvate kinase; Belongs to the pyruvate kinase family. (556 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa) |
| | EHHADH | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa) |
| | GLDC | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1005 aa) |
| | ME1 | Malic enzyme. (572 aa) |
| | IDH3G | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (393 aa) |
| | MDH1 | Malate dehydrogenase. (329 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | PRPS1 | Pribosyltran_N domain-containing protein. (318 aa) |
| | RPIA | Ribose 5-phosphate isomerase A. (311 aa) |
| | FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa) |
| | GLYCTK | Glycerate kinase. (523 aa) |
| | PSPH | Uncharacterized protein. (90 aa) |
| | ALDOC | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (375 aa) |
| | ACSS2 | Acyl-CoA synthetase short chain family member 2. (714 aa) |
| | ACAT2 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | DLAT | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (646 aa) |
| | TPI1 | Triosephosphate isomerase. (237 aa) |
| | GOT2 | Aspartate aminotransferase. (430 aa) |
| | HADHA | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa) |
