STRINGSTRING
DDB2 DDB2 ERCC6 ERCC6 RAD23A RAD23A RPA2 RPA2 CDK7 CDK7 CUL4B CUL4B ERCC8 ERCC8 GTF2H1 GTF2H1 POLD2 POLD2 POLD1 POLD1 POLE4 POLE4 RBX1 RBX1 RFC3 RFC3 PCNA PCNA POLE2 POLE2 MNAT1 MNAT1 POLE POLE CUL4A CUL4A CCNH CCNH DDB1 DDB1 POLD4 POLD4 ERCC4 ERCC4 ERCC3 ERCC3 GTF2H2 GTF2H2 RPA3 RPA3 CETN2 CETN2 RPA1 RPA1 GTF2H4 GTF2H4 GTF2H3 GTF2H3 XPA XPA RFC2 RFC2 BIVM BIVM RFC4 RFC4 RAD23B RAD23B RFC1 RFC1 POLD3 POLD3 GTF2H5 GTF2H5 POLE3 POLE3 XPC XPC ERCC1 ERCC1 LIG1 LIG1 RFC5 RFC5 ERCC2 ERCC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDB2Damage specific DNA binding protein 2. (427 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1491 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
RPA2Replication protein A2. (270 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
CUL4BCullin 4B; Belongs to the cullin family. (932 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
POLD1DNA polymerase. (1133 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (116 aa)
RBX1Ring-box 1. (108 aa)
RFC3Replication factor C subunit 3. (356 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
CUL4ACullin 4A; Belongs to the cullin family. (669 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
POLD4Uncharacterized protein. (107 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
RPA3Replication protein A3. (121 aa)
CETN2Centrin 2. (172 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
RFC2Replication factor C subunit 2. (320 aa)
BIVMBIVM-ERCC5 readthrough. (1640 aa)
RFC4Replication factor C subunit 4. (363 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
RFC1Replication factor C subunit 1. (1148 aa)
POLD3Uncharacterized protein. (459 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (146 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (946 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (297 aa)
LIG1DNA ligase. (919 aa)
RFC5Replication factor C subunit 5. (354 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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