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| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (803 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | EPHA2 | EPH receptor A2. (976 aa) |
| | RPS6KA6 | Ribosomal protein S6 kinase. (745 aa) |
| | MAPK8IP1 | Mitogen-activated protein kinase 8 interacting protein 1. (713 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa) |
| | CACNB3 | Calcium voltage-gated channel auxiliary subunit beta 3. (488 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (227 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa) |
| | MECOM | MDS1 and EVI1 complex locus. (1230 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (188 aa) |
| | IGF1 | IlGF domain-containing protein. (196 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | CACNA2D3 | Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1067 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | TAOK3 | TAO kinase 3. (898 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) |
| | DUSP2 | Tyrosine-protein phosphatase domain-containing protein. (170 aa) |
| | TAOK1 | TAO kinase 1. (1001 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (339 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa) |
| | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1. (1270 aa) |
| | CACNA1I | Calcium voltage-gated channel subunit alpha1 I. (2175 aa) |
| | EFNA4 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (201 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa) |
| | STK4 | Serine/threonine kinase 4. (487 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (490 aa) |
| | DUSP5 | Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (308 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1974 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1389 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (508 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | DAXX | Death domain associated protein. (748 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (371 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2298 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa) |
| | CACNA1G | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2364 aa) |
| | CACNB4 | Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | SRF | Serum response factor. (414 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | PLA2G4E | Phospholipase A2. (868 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase 11. (833 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) |
| | PTPN5 | Protein tyrosine phosphatase non-receptor type 5. (565 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa) |
| | RPS6KA4 | Ribosomal protein S6 kinase. (772 aa) |
| | ELK4 | ETS transcription factor ELK4. (431 aa) |
| | MAPK8IP2 | Mitogen-activated protein kinase 8 interacting protein 2. (692 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (316 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | MAP4K3 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1611 aa) |
| | NF1 | Neurofibromin 1. (2839 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (900 aa) |
| | FLNB | Filamin B. (2633 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (975 aa) |
| | DUSP8 | Uncharacterized protein. (345 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (339 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (537 aa) |
| | PGF | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (221 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | CDC42 | Uncharacterized protein. (191 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (240 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (812 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | CACNA2D4 | Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1154 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa) |
| | RASA1 | RAS p21 protein activator 1. (1047 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | ANGPT2 | Angiopoietin 2. (495 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | CACNB2 | Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa) |
| | RAC1 | Uncharacterized protein. (224 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | FLT1 | Uncharacterized protein. (736 aa) |
| | LOC100989777 | Uncharacterized protein. (191 aa) |
| | FGF21 | Uncharacterized protein. (147 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (986 aa) |
| | RRAS | RAS related. (176 aa) |
| | PDGFD | Platelet derived growth factor D. (329 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | RASGRP3 | RAS guanyl releasing protein 3. (690 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (780 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | DUSP16 | Dual specificity phosphatase 16. (665 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (2328 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (822 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (619 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (812 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1344 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1. (652 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (478 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (655 aa) |
| | EFNA3 | Ephrin A3; Belongs to the ephrin family. (238 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PPM1A | Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | FLNC | Filamin C. (2725 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (766 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (325 aa) |
| | PTPN7 | Protein tyrosine phosphatase non-receptor type 7. (464 aa) |
| | MAPKAPK2 | Protein kinase domain-containing protein. (365 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) |
| | RASA2 | RAS p21 protein activator 2. (929 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1372 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (162 aa) |
| | MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (802 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa) |
| | CACNG3 | Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa) |
| | ECSIT | ECSIT signalling integrator. (431 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | CDC25B | Cell division cycle 25B. (575 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (719 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1597 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1413 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) |
| | PPP5C | Serine/threonine-protein phosphatase. (503 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (758 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (174 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (408 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (843 aa) |
| | ARRB2 | Arrestin beta 2. (447 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | ATF4 | Activating transcription factor 4. (340 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa) |
| | RASGRP2 | RAS guanyl releasing protein 2. (610 aa) |
| | CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1126 aa) |
| | PLA2G4D | Phospholipase A2. (818 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | NGF | NGF domain-containing protein; Belongs to the NGF-beta family. (123 aa) |
| | TAOK2 | TAO kinase 2. (1234 aa) |
| | RAP1B | RAP1B, member of RAS oncogene family. (184 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | CACNG5 | Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | PTPRR | Protein tyrosine phosphatase receptor type R. (626 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1356 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1064 aa) |
| | MAP3K6 | Mitogen-activated protein kinase kinase kinase 6. (1250 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (947 aa) |
| | STK3 | Serine/threonine kinase 3. (467 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) |
| | CD14 | CD14 molecule. (384 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1386 aa) |
| | CACNA1B | Uncharacterized protein. (491 aa) |
| | MKNK2 | MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (260 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1321 aa) |
| | AREG | EGF-like domain-containing protein. (274 aa) |
| | EREG | Epiregulin. (169 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (549 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | RRAS2 | Uncharacterized protein. (169 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | TGFA | Transforming growth factor alpha. (181 aa) |
| | ELK1 | ETS transcription factor ELK1. (428 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa) |
| | PLA2G4C | Phospholipase A2 group IVC. (529 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1237 aa) |
| | DUSP9 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa) |
| | PPM1B | Protein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | RASGRP4 | RAS guanyl releasing protein 4. (699 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1201 aa) |
